Ebola Again Shows the International Health Regulations Are Broken

2016 ◽  
Vol 42 (2-3) ◽  
pp. 356-392 ◽  
Author(s):  
Trygve Ottersen ◽  
Steven J. Hoffman ◽  
Gaëlle Groux

Epidemics are among the greatest threats to humanity, and the International Health Regulations are the world's key legal instrument for addressing this threat. Since their revision in 2005, the IHR have faced two big tests: the 2009 H1N1 influenza pandemic and the 2014 Ebola epidemic in West Africa. Both exposed major shortcomings of the IHR, and both offered profound lessons for the future.The objective of this Article is twofold. First, we seek to compare the lessons learned from H1N1 and Ebola for reforming the IHR in order to test the hypothesis that they are similar. Second, we seek to examine the barriers to implementing these lessons and to identify strategies for overcoming those barriers.We find that the lessons from H1N1 and Ebola are indeed similar, and that opportunities to act on lessons from H1N1 were woefully missed. We identify many political barriers to global collective action and implementation of lessons for the IHR. On that basis, we describe strategies to overcome these barriers, which will hopefully be deployed now to reform the IHR before the policy window following Ebola closes, and before the inevitable next epidemic comes. The emerging threat of the Zika virus underscores that we have no time to waste.

2019 ◽  
Vol 34 (5) ◽  
pp. 1136-1144
Author(s):  
Won Suk Choi ◽  
Min Joo Choi ◽  
Ji Yoon Noh ◽  
Joon Young Song ◽  
Woo Joo Kim ◽  
...  

eLife ◽  
2016 ◽  
Vol 5 ◽  
Author(s):  
Ignacio Mena ◽  
Martha I Nelson ◽  
Francisco Quezada-Monroy ◽  
Jayeeta Dutta ◽  
Refugio Cortes-Fernández ◽  
...  

Asia is considered an important source of influenza A virus (IAV) pandemics, owing to large, diverse viral reservoirs in poultry and swine. However, the zoonotic origins of the 2009 A/H1N1 influenza pandemic virus (pdmH1N1) remain unclear, due to conflicting evidence from swine and humans. There is strong evidence that the first human outbreak of pdmH1N1 occurred in Mexico in early 2009. However, no related swine viruses have been detected in Mexico or any part of the Americas, and to date the most closely related ancestor viruses were identified in Asian swine. Here, we use 58 new whole-genome sequences from IAVs collected in Mexican swine to establish that the swine virus responsible for the 2009 pandemic evolved in central Mexico. This finding highlights how the 2009 pandemic arose from a region not considered a pandemic risk, owing to an expansion of IAV diversity in swine resulting from long-distance live swine trade.


2011 ◽  
Vol 18 (2) ◽  
pp. 158-166 ◽  
Author(s):  
Marion R. Sills ◽  
Matthew Hall ◽  
Harold K. Simon ◽  
Evan S. Fieldston ◽  
Nicholas Walter ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document