scholarly journals Origins of the 2009 H1N1 influenza pandemic in swine in Mexico

eLife ◽  
2016 ◽  
Vol 5 ◽  
Author(s):  
Ignacio Mena ◽  
Martha I Nelson ◽  
Francisco Quezada-Monroy ◽  
Jayeeta Dutta ◽  
Refugio Cortes-Fernández ◽  
...  
Keyword(s):  
Influenza A ◽  
Influenza Pandemic ◽  
H1n1 Influenza ◽  
Central Mexico ◽  
Genome Sequences ◽  
Viral Reservoirs ◽  
Long Distance ◽  
Conflicting Evidence ◽  
2009 H1n1 ◽  
H1n1 Influenza Pandemic

Asia is considered an important source of influenza A virus (IAV) pandemics, owing to large, diverse viral reservoirs in poultry and swine. However, the zoonotic origins of the 2009 A/H1N1 influenza pandemic virus (pdmH1N1) remain unclear, due to conflicting evidence from swine and humans. There is strong evidence that the first human outbreak of pdmH1N1 occurred in Mexico in early 2009. However, no related swine viruses have been detected in Mexico or any part of the Americas, and to date the most closely related ancestor viruses were identified in Asian swine. Here, we use 58 new whole-genome sequences from IAVs collected in Mexican swine to establish that the swine virus responsible for the 2009 pandemic evolved in central Mexico. This finding highlights how the 2009 pandemic arose from a region not considered a pandemic risk, owing to an expansion of IAV diversity in swine resulting from long-distance live swine trade.

scholarly journals Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand

2014 ◽  
Vol 1 (3) ◽  
Author(s):  
Shikha Garg ◽  
Sonja J. Olsen ◽  
Stefan Fernandez ◽  
Charung Muangchana ◽  
Kamonthip Rungrojcharoenkit ◽  
...  
Keyword(s):  
Influenza A ◽  
Influenza Pandemic ◽  
H1n1 Influenza ◽  
First Year ◽  
Serum Samples ◽  
Influenza A H1n1 ◽  
2009 H1n1 ◽  
Paired Serum ◽  
Sex With Men ◽  
H1n1 Influenza Pandemic

Abstract Among 368 Thai men who have sex with men with paired serum samples collected before and during the 2009 H1N1 influenza pandemic, we determined influenza A (H1N1)pdm09 seroconversion rates (≥4-fold rise in antibody titers by hemagglutination inhibition or microneutralization assays). Overall, 66 of 232 (28%) participants seroconverted after the first year of A(H1N1)pdm09 activity, and 83 of 234 (35%) participants seroconverted after the second year. Influenza A(H1N1)pdm09 seroconversion did not differ between human immunodeficiency virus (HIV)-infected (55 of 2157 [35%]) and HIV-uninfected (71 of 2211 [34%]) participants (P = .78). Influenza A(H1N1)pdm09 seroconversion occurred in approximately one third of our Thai study population and was similar among HIV-infected and HIV-uninfected participants.

scholarly journals Clinical and economic analysis of the 2009 H1N1 influenza pandemic among pregnant Korean women

2019 ◽  
Vol 34 (5) ◽  
pp. 1136-1144
Author(s):  
Won Suk Choi ◽  
Min Joo Choi ◽  
Ji Yoon Noh ◽  
Joon Young Song ◽  
Woo Joo Kim ◽  
...  
Keyword(s):  
Economic Analysis ◽  
Influenza Pandemic ◽  
H1n1 Influenza ◽  
Korean Women ◽  
2009 H1n1 ◽  
H1n1 Influenza Pandemic

scholarly journals Resource Burden at Children’s Hospitals Experiencing Surge Volumes During the Spring 2009 H1N1 Influenza Pandemic

2011 ◽  
Vol 18 (2) ◽  
pp. 158-166 ◽  
Author(s):  
Marion R. Sills ◽  
Matthew Hall ◽  
Harold K. Simon ◽  
Evan S. Fieldston ◽  
Nicholas Walter ◽  
...  
Keyword(s):  
Influenza Pandemic ◽  
H1n1 Influenza ◽  
Children's Hospitals ◽  
Children’S Hospitals ◽  
2009 H1n1 ◽  
H1n1 Influenza Pandemic

scholarly journals Emergency Department Visits for Antiviral Adverse Events during the 2009 H1N1 Influenza Pandemic

2011 ◽  
Vol 126 (3) ◽  
pp. 312-317 ◽  
Author(s):  
Maribeth C. Lovegrove ◽  
Nadine Shehab ◽  
Craig M. Hales ◽  
Kathy Poneleit ◽  
Elizabeth Crane ◽  
...  
Keyword(s):  
Emergency Department ◽  
Adverse Events ◽  
Influenza Pandemic ◽  
H1n1 Influenza ◽  
Emergency Department Visits ◽  
2009 H1n1 ◽  
H1n1 Influenza Pandemic
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