Infrared/Video Eng Recording of Eye Movements to Evaluate the Inferior Vestibular Nerve Using the Minimal Caloric Test

1988 ◽  
Vol 98 (3) ◽  
pp. 207-210 ◽  
Author(s):  
Fred H. Linthicum ◽  
Ron Waldorf ◽  
William M. Luxford ◽  
Sharon Caltogirone
Keyword(s):  
High Frequency ◽  
Auditory Brainstem ◽  
Vestibular Nerve ◽  
Caloric Test ◽  
Nerve Section ◽  
High Frequency Hearing Loss ◽  
Vestibular Response ◽  
Infrared Video ◽  
Inferior Vestibular Nerve ◽  
Brainstem Response

The technique was originally developed to test the inferior vestibular nerve in tumor suspects whose high-frequency hearing loss exceeded the capabilities of the auditory brainstem response tests and whose electronystagmographic results showed no significantly reduced vestibular response. The test has subsequently been found effective to demonstrate persistent singular nerve fiber function in patients with persistent vertigo after retrolabyrinthine vestibular nerve section.

Letter to the Editor

PEDIATRICS ◽  
1994 ◽  
Vol 94 (6) ◽  
pp. 950-952
Author(s):  
Michael J. M. Raffin ◽  
Gregory J. Matz
Keyword(s):  
Hearing Loss ◽  
Auditory Brainstem Response ◽  
High Frequency ◽  
Auditory Brainstem ◽  
Hearing Screening ◽  
Newborn Hearing Screening ◽  
High Frequency Hearing Loss ◽  
Universal Newborn Hearing Screening ◽  
Newborn Hearing ◽  
Brainstem Response

We thank Bess and Paradise, (1994)1 for bringing attention to some relevant issues related to universal newborn hearing screening. We note that their assertion that the effects of mild or moderate temporary hearing loss are "entirely speculative and perhaps nonexistent" may be somewhat overstated (see, for example, Teele, Klein, Chase, Menyuk, Rosner and associates, 1990).2 The assertion that click-evoked auditory brainstem response (ABR) may be used "... primarily to detect high-frequency hearing loss" is not warranted and misleading.

scholarly journals Chronic Oral Selegiline Treatment Mitigates Age-Related Hearing Loss in BALB/c Mice

2021 ◽  
Vol 22 (6) ◽  
pp. 2853
Author(s):  
Judit Szepesy ◽  
Viktória Humli ◽  
János Farkas ◽  
Ildikó Miklya ◽  
Júlia Tímár ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
Dose Range ◽  
Auditory Brainstem ◽  
High Frequency Hearing Loss ◽  
Age Related ◽  
Hearing Function ◽  
Brainstem Response ◽  
Aging Societies ◽  
Age Related Hearing Loss

Age-related hearing loss (ARHL), a sensorineural hearing loss of multifactorial origin, increases its prevalence in aging societies. Besides hearing aids and cochlear implants, there is no FDA approved efficient pharmacotherapy to either cure or prevent ARHL. We hypothesized that selegiline, an antiparkinsonian drug, could be a promising candidate for the treatment due to its complex neuroprotective, antioxidant, antiapoptotic, and dopaminergic neurotransmission enhancing effects. We monitored by repeated Auditory Brainstem Response (ABR) measurements the effect of chronic per os selegiline administration on the hearing function in BALB/c and DBA/2J mice, which strains exhibit moderate and rapid progressive high frequency hearing loss, respectively. The treatments were started at 1 month of age and lasted until almost a year and 5 months of age, respectively. In BALB/c mice, 4 mg/kg selegiline significantly mitigated the progression of ARHL at higher frequencies. Used in a wide dose range (0.15–45 mg/kg), selegiline had no effect in DBA/2J mice. Our results suggest that selegiline can partially preserve the hearing in certain forms of ARHL by alleviating its development. It might also be otoprotective in other mammals or humans.

Work-Related, Noise-Induced Hearing Loss: Evaluation Including Evoked Potential Audiometry

1994 ◽  
Vol 110 (2) ◽  
pp. 177-184 ◽  
Author(s):  
David M. Barrs ◽  
Lisa K. Althoff ◽  
Wesley W. O. Krueger ◽  
James E. Olsson
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Auditory Brainstem ◽  
Noise Induced Hearing Loss ◽  
Work Related ◽  
Middle Latency Response ◽  
Behavioral Thresholds ◽  
Valuable Adjunct ◽  
Brainstem Response ◽  
Magnetic Resonance Scanning

This article reviews the evaluation of 246 workers (492 ears) who underwent otologic and audiologic testing as part of a worker's compensation claim for work-related, noise-induced hearing loss. Tinnitus was present in 58% of the patients, but was rarely a major symptom. Other otologic symptoms or a history of ear disease were virtually nonexistent. Standard audiometry showed a downsloping, high-frequency sensorineural hearing loss in 85% of the ears tested, with only 37% having a characteristic “noise notch” at 4000 or 6000 hertz. Asymmetric hearing loss was not uncommon, with 48 patients (20%) undergoing magnetic resonance scanning, all of whom showed no central lesion responsible for the loss. Proven malingering was surprisingly uncommon (9%). In this study, evoked response audiometry was a valuable adjunct to confirm behavioral thresholds in the evaluation of possible work-related, noise-induced hearing loss. The middle latency response was more effective than the auditory brainstem response as a result of the high-frequency steepness of the audiometric curve.

The effect of coronavirus disease 2019 on the hearing system

2021 ◽  
pp. 1-5
Author(s):  
Ö Gedik ◽  
H Hüsam ◽  
M Başöz ◽  
N Tas ◽  
F Aksoy
Keyword(s):  
Auditory Brainstem Response ◽  
High Frequency ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Auditory Brainstem ◽  
Distortion Product ◽  
High Frequency Audiometry ◽  
Brainstem Response ◽  
Hearing System

Abstract Objective This study aimed to evaluate different auditory regions with audiological tests, based on the presumption that there may be damage to the structures in the hearing system after coronavirus disease 2019. Methods Twenty individuals with no history of coronavirus disease 2019 and 27 individuals diagnosed with coronavirus disease 2019 were compared. Pure tone, speech and extended high-frequency audiometry, acoustic immitansmetry, transient evoked and distortion product otoacoustic emissions testing, and auditory brainstem response testing were conducted. Results The pure tone audiometry and extended high-frequency mean threshold values were higher in the coronavirus disease 2019 group. The transient evoked otoacoustic emissions signal-to-noise ratios were bilaterally lower at 4 kHz in individuals with a coronavirus disease 2019 history. In the auditory brainstem response test, only the interpeak latencies of waves III–V were significantly different between groups. Conclusion Coronavirus disease 2019 may cause damage to the hearing system. Patients should be followed up in the long term with advanced audiological evaluation methods in order to determine the extent and level of damage.

scholarly journals Striatin is required for hearing and affects inner hair cells and ribbon synapses

2020 ◽  
Author(s):  
Prathamesh Thangaraj Nadar Ponniah ◽  
Shahar Taiber ◽  
Michal Caspi ◽  
Tal Koffler-Brill ◽  
Amiel A. Dror ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hair Cells ◽  
High Frequency ◽  
Cell Junctions ◽  
Scanning Electron Micrographs ◽  
High Frequency Hearing Loss ◽  
Inner Hair Cells ◽  
Brainstem Response ◽  
Deficient Mice ◽  
Cell Cell

AbstractStriatin, a subunit of the serine/threonine phosphatase PP2A, is a core member of the conserved striatin-interacting phosphatase and kinase (STRIPAK) complexes. The protein is expressed in the cell junctions between epithelial cells, which play a role in maintaining cell-cell junctional integrity. Since adhesion is crucial for the function of the mammalian inner ear, we examined the localization and function of striatin in the mouse cochlea. Our results show that in neonatal mice, striatin is specifically expressed in the cell-cell junctions of the inner hair cells, the receptor cells in the mammalian cochlea. Auditory brainstem response measurements of striatin-deficient mice indicated a progressive, high-frequency hearing loss, suggesting that striatin is essential for normal hearing. Moreover, scanning electron micrographs of the organ of Corti revealed a moderate degeneration of the outer hair cells in the middle and basal regions, concordant with the high-frequency hearing loss. Importantly, striatin-deficient mice show aberrant ribbon synapse maturation that may lead to the observed auditory impairment. Together, these results suggest a novel function for striatin in the mammalian auditory system.

scholarly journals Social drive and the evolution of primate hearing

2012 ◽  
Vol 367 (1597) ◽  
pp. 1860-1868 ◽  
Author(s):  
Marissa A. Ramsier ◽  
Andrew J. Cunningham ◽  
James J. Finneran ◽  
Nathaniel J. Dominy
Keyword(s):  
High Frequency ◽  
Social Complexity ◽  
Selective Pressure ◽  
General Rule ◽  
Auditory Brainstem ◽  
Published Data ◽  
Vocal Signals ◽  
Brainstem Response ◽  
Response Method ◽  
And Function

The structure and function of primate communication have attracted much attention, and vocal signals, in particular, have been studied in detail. As a general rule, larger social groups emit more types of vocal signals, including those conveying the presence of specific types of predators. The adaptive advantages of receiving and responding to alarm calls are expected to exert a selective pressure on the auditory system. Yet, the comparative biology of primate hearing is limited to select species, and little attention has been paid to the effects of social and vocal complexity on hearing. Here, we use the auditory brainstem response method to generate the largest number of standardized audiograms available for any primate radiation. We compared the auditory sensitivities of 11 strepsirrhine species with and without independent contrasts and show that social complexity explains a significant amount of variation in two audiometric parameters—overall sensitivity and high-frequency limit. We verified the generality of this latter result by augmenting our analysis with published data from nine species spanning the primate order. To account for these findings, we develop and test a model of social drive. We hypothesize that social complexity has favoured enhanced hearing sensitivities, especially at higher frequencies.

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