Clinical Features and Surgical Treatment of Cardiac Myxoma: Report of 18 Cases

2002 ◽  
Vol 10 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Kadir Durgut ◽  
Niyazi Görmüs ◽  
Mehmet Ozulku ◽  
Ufuk Özergin ◽  
Cevat Özpinar
Keyword(s):  
Cardiac Myxoma ◽  
Postoperative Mortality ◽  
Carney Complex ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Total Resection ◽  
Dominant Form ◽  
Mortality And Morbidity ◽  
Left Atrial Myxoma ◽  
Common Location

Myxomas are the most common benign primary cardiac tumors. As many patients with cardiac myxoma suffer from cerebral or systemic embolism, which are serious complications, diagnosis of the tumor is vital. Between 1990 and 2000, 18 patients (6 males, 12 females), aged 24 to 73 years (mean, 55.3 years), were operated on for cardiac myxoma. The most common location of the myxoma was the left atrium (78%), and the transseptal surgical approach was preferred (78%) as it allows total resection of the left atrial myxoma along with its pedicle. Carney complex, a familial autosomal dominant form of atrial myxoma, was not found in any of the patients. There had been no operative or postoperative mortality and morbidity. The mean postoperative follow-up period was 5 years (mean, 1 to 10 years). No recurrence had been seen. We believe that the transseptal approach, in allowing total resection of the myxoma, prevents recurrence.

Left Atrial Myxoma and Antiphospholipid Syndrome—A Case Report

2021 ◽  
Author(s):  
Mijo Meter ◽  
Diana Meter ◽  
Toni Ceprnja ◽  
Dijana Perkovic
Keyword(s):  
Case Report ◽  
Antiphospholipid Syndrome ◽  
Lupus Erythematosus ◽  
Left Atrial ◽  
Imaging Modality ◽  
Cardiac Myxoma ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Left Atrial Myxoma ◽  
Initial Imaging

AbstractCardiac myxoma (CM) is the most frequent type of primary cardiac neoplasm and is responsible for 58 to 80% of primary cardiac tumors. The antiphospholipid syndrome (APS) occurs most commonly in the systemic lupus erythematosus but it can be also found in other conditions. The coexistence of CM and APS is rarely described in the literature. We report an unusual case of the left atrial myxoma and concomitant APS in a female patient who presented with right-sided hemiplegia. Although rare, we must think about the CM in patients with a newly diagnosed APS and left atrial mass. Nevertheless, we must make a distinction from other possible cardiac structures, especially atrial thrombus. Transthoracic echocardiography is the most frequently used initial imaging modality to detect CM. The aim of this case report was to emphasize that additional imaging modalities and multidisciplinary approach are mandatory in making a proper diagnosis and to choose a further treatment strategy.

scholarly journals A case report of left atrial myxoma presenting with amnesia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sadegh Shabab ◽  
Majid Erfanzadeh ◽  
Shamsa Ahmadian ◽  
Maryam Mahmoudabady ◽  
Naser Mazloum
Keyword(s):  
Left Atrial ◽  
Cardiac Myxoma ◽  
Common Type ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Surgery Complications ◽  
Case Presentation ◽  
Left Atrial Myxoma ◽  
Primary Cardiac Tumors

Abstract Background Primary cardiac tumors are rare, and approximately 90% of them are benign. Myxoma is the most common type of these tumors occurring in the left atrium in 75–85% of cases. The tumor can cause the left atrio-ventricular valve obstruction and embolization phenomenon. Case presentation We reported a case of 54-year-old man with complaints of dyspenea and amnesia. In our patient, transthoracic echocardiography revealed a mass of 28*63 mm attached to the upper intra-atrial septum, which was prolapsing through the mitral valve into the left ventricle during diastole, being indicative of the left atrial myxoma. On examination, he was alert and conversant, and no pathological abnormality was observed in the examination of cardiovascular, gastrointestinal, respiratory, hepatic, renal and nervous systems. After myxoma diagnosis, the tumor was removed under cardiac surgery and discharged under good conditions. In the telephone follow-up after discharge, the patient recovered and did not report the disease and surgery complications. Conclusions Patients with cardiac myxoma are usually asymptomatic, but they may have manifestations related to the embolism phenomenon or intracardiac obstruction. Therefore, myxoma may represent an emergency. Surgery should be performed as soon as possible. If surgery is delayed, the patient may suffer from serious and irreversible complications, such as stroke and cardiac arrest.

scholarly journals Left Atrial Myxoma Presenting As a Stroke – An Unusual Case Scenario

2021 ◽  
Vol 9 (1) ◽  
pp. 84-86
Author(s):  
Pinninti Mounika ◽  
sandhyika B ◽  
Ravinder Reddy Kasturi ◽  
Nikhil Mudgalkar ◽  
Aashish Baviskar
Keyword(s):  
Cardiac Tumor ◽  
Unusual Case ◽  
Cardiac Myxoma ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Case Scenario ◽  
Left Atrial Myxoma ◽  
Female Predominance ◽  
Benign Cardiac Tumor ◽  
Primary Cardiac Tumors

The most common benign cardiac tumor is cardiac myxoma,accounting for around 50% of all primary cardiac tumors. Cardiac myxoma is an uncommon cause ofcardioembolic stroke.Overall,cardioembolic stroke accounts for approximately 30% of all ischemic stroke of which 0.5% of cardioembolic strokes are attributable to a cardiac myxoma.It has an annual incidence of around 0.5 cases per one million people with female predominance. Early diagnosis is necessary to prevent its devastating complications such as embolic stroke and sudden cardiac death.We present a relatively rare case of an acute stroke as a first and only manifestation of an atrial myxoma

scholarly journals Rare association of acromegaly with left atrial myxoma in Carney's complex due to novel PRKAR1A mutation

2014 ◽  
Vol 2014 ◽  
Author(s):  
Shweta Birla ◽  
Sameer Aggarwal ◽  
Arundhati Sharma ◽  
Nikhil Tandon
Keyword(s):  
Left Atrial ◽  
Cardiac Myxoma ◽  
Rare Condition ◽  
Carney Complex ◽  
Atrial Myxoma ◽  
Magnetic Resonance Imaging Scan ◽  
Insertion Mutation ◽  
List Type ◽  
Left Atrial Myxoma ◽  
Pigmented Lesions

Summary Carney complex (CNC) is a rare autosomal dominant syndrome characterized by pigmented lesions of the skin and mucosae along with cardiac, endocrine, cutaneous, and neural myxomatous tumors. Mutations in the PRKAR1A gene have been identified in ∼70% of the CNC cases reported worldwide. A 30-year-old male was referred to the endocrinology clinic with suspected acromegaly. He had a history of recurrent atrial myxoma for the past 8 years for which he underwent repeated surgeries. Presently, he complained of having headache, excessive snoring, sweating, and also noticed increase in his shoe size. Evaluation for acromegaly revealed elevated levels of GH in random as well as in suppressed condition. Magnetic resonance imaging scan revealed enlarged sella with microadenoma in the left anterior pituitary. Screening of PRKAR1A gene was carried out for the patient, his parents and siblings who were available and willing to undergo the test. The patient was diagnosed to have the rare CNC syndrome characterized by recurrent atrial myxoma and acromegaly due to a novel 22 bp insertion mutation in PRKAR1A which was predicted to be deleterious by in silico analysis. Screening the available family members revealed the absence of this mutation in them except the elder brother who also tested positive for this mutation. The present study reports on a novel PRKAR1A insertion mutation in a patient with acromegaly and left atrial myxoma in CNC. Learning points Identification of a novel deleterious PRKAR1A insertion mutation causing CNC. It is important that patients with cardiac myxoma be investigated for presence of endocrine overactivity suggestive of CNC. PRKAR1A mutation analysis should be undertaken in such cases to confirm the diagnosis in the patients as well as first degree relatives. This case highlights an important aspect of diagnosis, clinical course, and management of this rare condition.

scholarly journals Early recurrent left atrial myxoma in a teenager with de novo mutation of Carney complex

2011 ◽  
Vol 17 (2) ◽  
pp. 108 ◽  
Author(s):  
MilaS Stajevic ◽  
VladimirD Kuburovic ◽  
VladislavA Vukomanovic ◽  
SlavisaM Djuricic
Keyword(s):  
Left Atrial ◽  
De Novo ◽  
Carney Complex ◽  
Atrial Myxoma ◽  
De Novo Mutation ◽  
Left Atrial Myxoma

scholarly journals Left Atrial Myxoma Hypervascularized from the Right Coronary Artery: An Interesting Cath Lab Finding

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Marcos Danillo Peixoto Oliveira ◽  
Adriano Ossuna Tamazato ◽  
Fernando Roberto de Fazzio ◽  
Luiz J. Kajita ◽  
Expedito E. Ribeiro ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Left Atrial ◽  
Rare Case ◽  
Vascular Supply ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Left Atrial Myxoma ◽  
The Right ◽  
Primary Cardiac Tumors

Primary cardiac tumors are rare and approximately half of them are atrial myxomas. They rarely remain asymptomatic, especially if large. The imaging of a myxoma by contrast dye during coronary angiography is an infrequent sign, which clarifies the vascular supply of the tumor. We report herein an interesting and rare case of a left atrial myxoma hypervascularized from the right coronary artery.

scholarly journals Giant left atrial myxoma presenting as cerebral embolism

2021 ◽  
pp. 93-97
Keyword(s):  
Left Atrial ◽  
Heart Diseases ◽  
Atrial Myxoma ◽  
Cerebral Stroke ◽  
Primary Tumors ◽  
Mortality And Morbidity ◽  
Left Atrial Myxoma ◽  
Cardiac Neoplasms ◽  
Systemic Embolization ◽  
Rheumatic Heart

Primary cardiac neoplasms are uncommon with an overall incidence of 0.0017 to 0.02%. The majority of these tumors are benign and half of these tumors are myxomas. About 75% of them are located in the left atrium. Acute embolic cerebral stroke is major problem with increased mortality and morbidity. Embolus arising from cardiac origin costitutes about 20% of ischemic strokes. Atrial fibrillation is cause of more than 50% of cardiogenic emboli. Congenital heart diseases, such as atrial septal defect, patent foramen ovale, prosthetic and rheumatic heart valvular disease, dilated cardiomyopathy and endocarditis are predisposing factors for cardiogenic emboli. Emboli from primary tumors of the heart are extremely rare, with an incidence of 0.02 %. Myxoma is a potential source of systemic embolization to the brain or peripheral arteries. Thus, cerebral stroke may be the first manifestation of the presence of left atrial myxoma.

scholarly journals Recurrent left atrial myxoma in Carney complex

Medicine ◽  
2018 ◽  
Vol 97 (12) ◽  
pp. e0247 ◽  
Author(s):  
Liaoyuan Wang ◽  
Qing Wang ◽  
Yue Zhou ◽  
Qian Xue ◽  
Xiao Sun ◽  
...  
Keyword(s):  
Left Atrial ◽  
Carney Complex ◽  
Atrial Myxoma ◽  
Left Atrial Myxoma

scholarly journals P853 Bilateral lower limb ischemia in a healthy young man what if the heart was hiding the etiology

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
M Mouadili ◽  
A Tamdy ◽  
B El Fatmi ◽  
S Elkarimi
Keyword(s):  
Popliteal Artery ◽  
Lower Limb ◽  
Cardiac Myxoma ◽  
Clinical Manifestations ◽  
Limb Ischemia ◽  
Atrial Myxoma ◽  
Surgical Removal ◽  
Left Atrial Myxoma ◽  
Tibial Arteries ◽  
The Right

Abstract Cardiac myxoma is the most common benign cardiac tumor with diverse nonspecific clinical manifestations; moreover, atrial myxoma embolization to the peripheral vessels is rare. A 24-year-old man presented tothe emergency departement complaining ofpain and coldness of his two lower extremities. The right femoral pulse was normally felt while the pulses of the left lower limb from the femoral down to the posterior and anterior tibial arteries were not felt. Bilateral thrombectomy was performed on emergency basisand a fatty-like mass from the left femoral artery was removed. The histological examination of this mass was suggestive of myxoma.So, transthoracic echocardiography was done and confirmed the diagnosis of myxoma that was seen in the left atrium and measuring about 10X6 cm in its maximal dimensions. Surgical removal of the myxoma was done later and the patient recovered uneventfully. Conclusion Although myxomas are rare, they should be considered in the differential diagnosis of peripheral embolic disease, especially when an embolic event occurs in a young adult without evidence of endocarditis or arrhythmia. Echocardiography is the modality of choice for diagnosis and follow-up of this type of tumors. FIGURE 1: CTA (computed tomography angiography) showing Occlusion of the left popliteal artery and occlusion of the distal part of the right popliteal artery FIGURE 2: macroscopic view of gelatinous left atrial myxoma

scholarly journals Left Atrial Myxoma with Tricuspid Regurgitation: Pathophysiology, Diagnostic Approach, and Management

2015 ◽  
pp. 28-3
Author(s):  
Prima Almazini ◽  
Bambang Budi Siswanto ◽  
Nani Hersunarti ◽  
Rarsari Soerarso ◽  
Amiliana M Soesanto
Keyword(s):  
Cardiac Myxoma ◽  
Clinical Manifestations ◽  
Definitive Treatment ◽  
Surgical Removal ◽  
Cardiac Tumors ◽  
Gold Standard Method ◽  
Left Atrial Myxoma ◽  
Associated Conditions ◽  
Cardiac Myxomas ◽  
Primary Cardiac Tumors

Cardiac myxomas are the most common primary cardiac tumors. Myxoma are more common in women. Clinical manifestations can mimic many cardiac and noncardiac conditions. Transthoracic echocardiography (TTE) is the gold standard method in the diagnosis of cardiac myxoma. The management of cardiac myxoma are medical therapy for the treatment of associated conditions and surgical removal as the definitive treatment.

Sign in / Sign up

Export Citation Format

Share Document