Finite element analysis to model complex mitral valve repair

This paper describes work in progress aimed at developing an interactive modeling tool that assists engineers with the task of physical modeling in finite element analysis. Physical modeling precedes the numerical simulation phase of finite element analysis and involves applying modeling idealizations to real world physical systems so that complex engineering problems are more amenable to numerical computation. In the paper, the nature of physical modeling is explored, a cognitive model of how engineers are thought to model complex problems is described and based on this model a knowledge-based modeling assistant is proposed. The AI approach taken is based on Chandrasekaran's propose-critique-modify design model adapted for the task of physical modeling. Within this framework, the AI paradigms of case-based reasoning, derivational analogy and model-based reasoning are exploited. By representing fundamental thermal modeling scenarios as cases, complex physical systems can be modeled in a piecewise fashion. Derivational analogy permits generative adaptation of retrieved cases by using model-based engineering traces thereby providing a basis for critiquing case solutions. An initial prototype is described which has been implemented for the domain of convection heat transfer analysis.

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QUANTIFICATION OF IN VIVO MITRAL VALVE MATERIAL PROPERTIES USING INVERSE FINITE ELEMENT ANALYSIS

Journal of Biomechanics ◽

10.1016/s0021-9290(08)70119-2 ◽

2008 ◽

Vol 41 ◽

pp. S119

Author(s):

Gaurav Krishnamurthy ◽

Daniel B. Ennis ◽

Akinobu Itoh ◽

Wolfgang Bothe ◽

Julia Swanson ◽

...

Keyword(s):

Finite Element Analysis ◽

Finite Element ◽

Mitral Valve ◽

Material Properties ◽

Element Analysis ◽

Inverse Finite Element Analysis

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Finite element analysis on the influence of the papillary muscle locations on stress distribution of the stentless mitral valve with a function of chordae tendineae

The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME ◽

10.1299/jsmebio.2017.29.1b24 ◽

2017 ◽

Vol 2017.29 (0) ◽

pp. 1B24

Author(s):

Jumpei TAKADA ◽

Xiaodong ZHU ◽

Kazuaki USUI ◽

Keitarou MAHARA ◽

Mituo UMEZU ◽

...

Keyword(s):

Finite Element Analysis ◽

Finite Element ◽

Mitral Valve ◽

Stress Distribution ◽

Papillary Muscle ◽

Chordae Tendineae ◽

Element Analysis ◽

Stentless Mitral Valve

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Selectively Compliant Annuloplasty Ring to Enable Annular Dynamics in Mitral Valve Repair Evaluated by In-Vitro Stereovision

2020 Design of Medical Devices Conference ◽

10.1115/dmd2020-9034 ◽

2020 ◽

Author(s):

Samuel Frishman ◽

Annabel M. Imbrie-Moore ◽

Mark R. Cutkosky ◽

Ali Kight ◽

Ileana Pirozzi ◽

...

Keyword(s):

Finite Element Analysis ◽

Mitral Valve ◽

Valve Repair ◽

Element Analysis ◽

Orifice Area ◽

Ring Dynamics ◽

Motion Profile ◽

Anterior Posterior

Abstract Mitral valve (MV) annular dynamics are critical to the long term efficacy of MV repair. Today’s annuloplasty rings, used to restore MV function, impose significant constraints on the motion profile of the MV annulus. We present a selectively compliant ring that provides sufficient stiffness to stabilize a diseased annulus while allowing physiological annular dynamics. Ring design is informed by a finite element analysis and experimentally evaluated with in-vitro stereophotogrammetry. We compare the ring dynamics to commercially available semi-rigid rings as well as values found in literature for healthy annuli. The results demonstrate that motion of the selectively compliant ring is significantly closer to that of a healthy annulus based on standard metrics that define MV annular movement. Specifically, the metrics for the new ring compare to those in literature as follows: change in orifice area 12.5 ± 3% vs.10 ± 2%; change in anterior-posterior diam. 5.4 ± 0.3% vs. 7 ± 1%; change in inter-commissural diam. 6.6 ± 1.3% vs. 5 ± 1%.

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A novel finite element-based patient-specific mitral valve repair: virtual ring annuloplasty

Bio-Medical Materials and Engineering ◽

10.3233/bme-130816 ◽

2014 ◽

Vol 24 (1) ◽

pp. 341-347 ◽

Cited By ~ 13

Author(s):

Ahnryul Choi ◽

Yonghoon Rim ◽

Jeffrey S. Mun ◽

Hyunggun Kim

Keyword(s):

Finite Element ◽

Mitral Valve ◽

Mitral Valve Repair ◽

Patient Specific ◽

Valve Repair ◽

Ring Annuloplasty

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Quantification of In Vivo Stresses in the Ovine Anterior Mitral Valve Leaflet

ASME 2008 Summer Bioengineering Conference, Parts A and B ◽

10.1115/sbc2008-192295 ◽

2008 ◽

Author(s):

Gaurav Krishnamurthy ◽

Akinobu Itoh ◽

Wolfgang Bothe ◽

Daniel B. Ennis ◽

Julia C. Swanson ◽

...

Keyword(s):

Finite Element Analysis ◽

Finite Element ◽

Mitral Valve ◽

Material Properties ◽

Element Analysis ◽

Mitral Valve Leaflet ◽

Mitral Valves ◽

Mitral Repair ◽

Inverse Finite Element Analysis

Mitral valve (MV) disease affects millions worldwide. An important goal of present-day heart valve research is to create bioengineered tissue valves to replace diseased mitral valves, if it is judged that mitral repair will not be durable. The design of such valves will pivot on understanding the stresses acting in the native MV leaflets to design a bioprosthesis which will withstand these stresses. In order to quantify such stresses in vivo, we utilized radiopaque marker technology and performed an “inverse” finite element analysis of the resulting 4-D data to determine the material properties of the anterior MV leaflet in the beating ovine heart. We then used these material properties in a “forward” finite element analysis to estimate the stresses in the native anterior MV leaflet.

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