Antidepressant drugs and the cardiovascular system: a comparison of tricylics and selective serotonin reuptake inhibitors and their relevance for the treatment of psychiatric patients with cardiovascular problems

1997 ◽  
Vol 11 (1) ◽  
pp. 83-92 ◽  
Author(s):  
Nick Coupland ◽  
Susan Wilson ◽  
David Nutt
Keyword(s):  
Cardiovascular System ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Psychiatric Patients ◽  
Antidepressant Drugs ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
System A

scholarly journals Patterns of Antidepressant Prescriptions for the Treatment of Depression: A Scoping Review

2020 ◽  
Author(s):  
Nirmal Raj Marasine ◽  
Sabina Sankhi ◽  
Rajendra Lamichhane ◽  
Nim Bahadur Dangi
Keyword(s):  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Antidepressant Drugs ◽  
Public Health Problem ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Tolerability Profile ◽  
High Morbidity ◽  
Global Public Health ◽  
Treatment Of Depression

Abstract Introduction: Depression is an important global public health problem due to its relatively high lifetime prevalence and significant disability caused by it. It is associated with functional impairment and high morbidity and mortality. Antidepressant medication is considered to be the best treatment option for depressionMethod: Literature searches (2000-2019) were performed using PubMed, HINARI and Google Scholar that analyze the pattern of prescription of antidepressants among the patients of depression. .Results: Females suffered from depression more than their male counterparts. Married people, housewives, lower income people, employees and highly educated people suffered more from depression. Selective Serotonin Reuptake Inhibitors (SSRI) like Sertraline, was found out to be the most preferred antidepressant among the depressive patients. Conclusion: Our Study suggested that out of five major antidepressant drugs being available for the treatment of depression, selective serotonin reuptake inhibitors are preferred over others because of their better side effect and tolerability profile.

scholarly journals Monitoring of adverse drug reactions to antidepressant drugs in a teaching hospital

2017 ◽  
Vol 6 (4) ◽  
pp. 933 ◽  
Author(s):  
Swetha Munoli ◽  
Soumya B. Patil
Keyword(s):  
Adverse Events ◽  
Adverse Drug Reactions ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Tricyclic Antidepressants ◽  
Antidepressant Drugs ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Drug Reactions ◽  
Medical Sciences

Background: Adverse drug reactions (ADRs) are considered among the leading causes of morbidity and mortality. Adverse drug reactions are important determinants of non-adherence to antidepressant treatment, but their assessment is complicated by overlap with depressive symptoms and lack of reliable self-report measures The present study was therefore undertaken to monitor the ADRs of the antidepressant in the psychiatric outpatient unit of Raichur Institute of Medical Sciences, Raichur, Karnataka, IndiaMethods: Study was conducted from December 2012 to November 2013, the   patients on antidepressant drugs from psychiatry out- patient department (OPD) of Raichur Institute of Medical Sciences were considered for analysis. The patients were diagnosed by consultant psychiatrist. Data was collected in standard questionnaire format. All patients diagnosed with psychiatric disorder as per ICD 10 criteria and receiving treatment with antidepressant were included. Assessment of causality and severity of recorded adverse events was done using WHO assessment scale and modified Siegel and Hartwig Scale respectively.Results: In our study 74 adverse drug reactions(ADRs) were seen among 52 cases, total 263 cases were screened.CNS and Anticholinergic side effects were most common adverse drug reactions noted. Tricyclic antidepressants (TCA) and Selective serotonin reuptake inhibitors (SSRIs) were the drugs causing maximum ADRs. Assessment of causality and severity of recorded adverse events showed possible to probable and mild to moderate severity respectively.Conclusions: CNS and Anticholinergic side effects were most common adverse drug reactions noted. Tricyclic antidepressants (TCA) were most commonly prescribed drugs followed by Selective serotonin reuptake inhibitors (SSRIs). Tricyclic antidepressants (TCA) and Selective serotonin reuptake inhibitors (SSRIs) accounted for most of ADRs (87.8%). Assessment of causality of recorded adverse events showed no certain cause and assessment of severity of recorded adverse events showed no severe cases.

Evidence Into Practice: Prescribing Selective Serotonin Reuptake Inhibitors

1998 ◽  
Vol 14 (2) ◽  
pp. 387-391 ◽  
Author(s):  
Nick Freemantle ◽  
James M. Mason ◽  
Ian Watt
Keyword(s):  
Primary Care ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Descriptive Analysis ◽  
Antidepressant Drugs ◽  
Health Technology ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Prescribing Trends ◽  
Release Of Information

AbstractThis descriptive analysis examines prescribing trends of antidepressants in English primary care, providing analysis of NHS reimbursement data for groups of antidepressants between 1989 and 1994. Prescribing trends seem unaffected by the release of information on the effectiveness and costeffectiveness of antidepressant drugs. We found that simple distribution of the results of health technology assessments may not be sufficient to influence practice.

scholarly journals Use of Antidepressants among Patients Diagnosed with Depression: A Scoping Review

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Nirmal Raj Marasine ◽  
Sabina Sankhi ◽  
Rajendra Lamichhane ◽  
Nabin Raj Marasini ◽  
Nim Bahadur Dangi
Keyword(s):  
Reuptake Inhibitor ◽  
Serotonin Reuptake ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Antidepressant Drugs ◽  
Serotonin Reuptake Inhibitors ◽  
Selective Serotonin ◽  
Tolerability Profile ◽  
Highly Educated ◽  
Treatment Of Depression ◽  
Antidepressant Use

Introduction. Depression is a major global health problem with a relatively high lifetime prevalence and significant disability. Antidepressants are the most effective medications used for the treatment of depression. Hence, this study is aimed at summarizing the studies on antidepressant use among patients diagnosed with depression. Method. PubMed, Embase, Web of Science, Scopus, and Google Scholar were searched for literature (2000-2019) using keywords such as depression, drug utilization, antidepressants, prescription, serotonin reuptake inhibitor, serotonin and norepinephrine reuptake inhibitor, tricyclic antidepressants, and atypical antidepressants. Results. Antidepressant users were mostly females, married people, housewives, lower-income people, employees, and highly educated people, as they were found to be more prone to develop depression than their counterparts. Selective serotonin reuptake inhibitors (SSRIs), such as sertraline, were most commonly prescribed among depressive patients. Conclusion. Our study suggested that out of five major antidepressant drugs available for the treatment of depression, selective serotonin reuptake inhibitors are preferred over others because of their better side effects and tolerability profile.

Sign in / Sign up

Export Citation Format

Share Document