Distribution of Coronary Atherosclerosis and its Correlation to Metabolic Risk Factors and Femoral Atherosclerosis

1994 ◽  
Vol 35 (5) ◽  
pp. 481-486
Author(s):  
L. Bergstrand ◽  
H. Bylund ◽  
U. Erikson ◽  
G. Helmius ◽  
C. Lidell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Arteries ◽  
Coronary Atherosclerosis ◽  
Coronary Artery Stenosis ◽  
Proximal Part ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Previous Myocardial Infarction ◽  
Coronary Stenoses ◽  
The Right

Coronary angiography was performed in 216 men of whom 78 also had a cine-angiogram of one femoral artery. Stenoses of the coronary arteries were measured with a pair of calipers and the femoral angiograms were computer-analysed. The patients were divided into 2 groups according to whether the bulk of the coronary stenoses affected the central or the peripheral part of the coronary arteries. The groups were investigated regarding differences in lipid and metabolic risk factors. Coronary atherosclerosis was most often found in the proximal part of the right coronary arteries. No significant correlation between coronary and femoral atherosclerosis was found. Previous myocardial infarction was associated with more coronary artery stenosis (p < 0.003). No pattern of risk factors was found to discriminate between central and peripheral coronary atherosclerosis.

Correlation of Metabolic Risk Factors with Sessile Serrated Lesions

2020 ◽  
Vol 29 (2) ◽  
pp. 175-179
Author(s):  
Melania Macarie ◽  
Simona Bataga ◽  
Simona Mocan ◽  
Monica Pantea ◽  
Razvan Opaschi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Statistical Significance ◽  
Interval Cancer ◽  
Metabolic Risk Factors ◽  
Control Group ◽  
Anatomical Site ◽  
Metabolic Risk ◽  
Right Colon ◽  
Serrated Lesions ◽  
The Right

Background and Aims: The importance of sessile serrated lesions (SSLs) in the pathogenesis of colorectal carcinoma has been recently established. These are supposed to cause the so-called “interval cancer”, having a rapidly progressive growth and being difficult to detect and to obtain an endoscopic complete resection. We aimed to establish the most important metabolic risk factors for sessile serrated lesions. Methods: We performed a retrospective case-control study, on a series of 2918 consecutive patients who underwent colonoscopy in Gastroenterology and Endoscopy Unit, County Clinical Emergency Hospital, Târgu-Mureș, Romania between 1 st of January 2015-31 th of December 2017. In order to evaluate the metabolic risk factors for polyps’ development, enrolled participants were stratified in two groups, a study group, 33 patients with SSLs lesions, and a control group, 138 patients with adenomatous polyps, selected by systematic sampling for age and anatomical site. Independent variables investigated were: gender, smoking, alcohol consumption, obesity, arterial hypertension, diabetes, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, nonalcoholic liver disease. Results: For SSLs the most common encountered localization was the right colon in 30.55% of cases. By comparative bivariate analysis between SSLs group and control group, it was observed that hypertension (p=0.03, OR 2.33, 95 %CI 1.03-5.24), obesity (p=0.03, OR 2.61, 95 %CI 1.08-6.30), hyperuricemia (p=0.04, OR 2.72, 95 %CI 1.28-7.55), high cholesterol (p=0.002, OR 3.42; 95 %CI 1.48-7.87), and high triglycerides level (p=0.0006, OR 5.75; 95 %CI 1.92-17.2) were statistically associated with SSLs development. By multivariate analysis hypertension and hypertriglyceridemia retained statistical significance. Conclusions: Our study showed that the highest prevalence of SSLs was in the right colon and hypertension and increased triglycerides levels were associated with the risk of SSLs development. These risk factors are easy to detect in clinical practice and may help identifying groups with high risk for colorectal cancer, where screening is recommended.

Distribution of Coronary Atherosclerosis and its Correlation to Metabolic Risk Factors and Femoral Atherosclerosis

1994 ◽  
Vol 35 (5) ◽  
pp. 481-486 ◽  
Author(s):  
L. Bergstrand ◽  
H. Bylund ◽  
U. Erikson ◽  
G. Helmius ◽  
C. Lidell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Atherosclerosis ◽  
Metabolic Risk Factors ◽  
Metabolic Risk

Distribution of Coronary Atherosclerosis and its Correlation to Metabolic Risk Factors and Femoral Atherosclerosis

1994 ◽  
Vol 35 (5) ◽  
pp. 481-486
Author(s):  
L. Bergstrand ◽  
H. Bylund ◽  
U. Erikson ◽  
G. Helmius ◽  
C. Lidell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Atherosclerosis ◽  
Metabolic Risk Factors ◽  
Metabolic Risk

scholarly journals EPICARDIAL OBESITY AND A RANGE OF METABOLIC RISK FACTORS RELATION WITH THE PREVALENCE INDEX OF CORONARY ATHEROSCLEROSIS

2015 ◽  
Vol 14 (2) ◽  
pp. 35-40 ◽  
Author(s):  
G. A. Chumakova ◽  
N. G. Veselovskaya ◽  
A. V. Ott ◽  
O. V. Gritsenko
Keyword(s):  
Risk Factors ◽  
Coronary Atherosclerosis ◽  
Coronary Arteriography ◽  
High Risk Group ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Obese Patients ◽  
Prevalence Index ◽  
Epicardial Fat Tissue ◽  
Factor Α

Aim. To assess the relation of epicardial fat tissue thickness (EFTT) and other metabolic risk factors with the index of coronary atherosclerosis Spread (CASI) in obese patients. Material and methods. Totally 186 men included (54,4±9,1 y.o.) with coronary heart disease (CHD) and obesity. By the results of coronary arteriography we calculated Gensini Score of CASI. All patients underwent laboratory tests with the measurement of basic and additional metabolic risk factors and echocardiography with EFFT measurement. Results. By the data of regression analysis we selected 7 predictors significantly related to EFTT: CASI (β=0,390), resistine (β=0,453), glucose (β=152), adiponectine (β=-0,175), high density lipoproteides cholesterol (β=-0,138), interleukine-6 (β=0,118), and tumor necrosis factor-α (β=0,117). Measurement of the predictors values led in 52,1% to the changes of CASI value (R²=0,521). Conclusion. In obese patients the assessment of the parameters described makes possible to circle a high risk group for unsymptomatic CHD forms with the aim for on-time investigation of patients and for early preventive interventions.

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