Impaired vagal activity to meal in patients with functional dyspepsia and delayed gastric emptying

Objective This study was performed to investigate impaired vagal activity to meal in patients with functional dyspepsia (FD) with delayed gastric emptying (GE). Methods Eighty-five patients were studied. GE parameters, including those in the overall and proximal stomach, were measured by GE functional tests at the Department of Nuclear Medicine. Autonomic nervous function was tested by spectral analysis of heart rate variability (HRV). The vagal activity and sympathetic activity were analyzed by recording the power in the high-frequency component (HF), low-frequency component (LF), and LF/HF ratio. Results Overall and proximal GE were delayed in 47.2% and 50.9% of the patients, respectively. Spectral analysis of HRV showed that the HF in patients with delayed proximal GE was significantly lower and that the LF/HF ratio was significantly higher than those in patients with normal proximal GE after a meal. Conclusion Delayed proximal GE might be caused by disrupted sympathovagal balance as a result of decreased vagal activity after a meal. Improvement in vagal activity may constitute an effective treatment method for patients with FD.

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Extreme prolongation of expiration breathing: Effects on electroencephalogram and autonomic nervous function

Mental Illness ◽

10.1108/mi.2018.7881 ◽

2018 ◽

Vol 10 (2) ◽

pp. 62-65

Author(s):

Teruhisa Komori

Keyword(s):

High Frequency ◽

Frequency Ratio ◽

Low Frequency ◽

Frequency Component ◽

Small Sample ◽

High Frequency Component ◽

Deep Breathing ◽

Continuous Eeg ◽

Nervous Function ◽

Electrocardiogram Ecg

To clarify the physiological and psychological effects of deep breathing, the effects of extreme prolongation of expiration breathing (Okinaga) were investigated using electroencephalogram (EEG) and electrocardiogram (ECG). Participants were five male Okinaga practitioners in their 50s and 60s. Participants performed Okinaga for 31 minutes while continuous EEG and ECG measurements were taken. After 16 minutes of Okinaga, and until the end of the session, the percentages of theta and alpha 2 waves were significantly higher than at baseline. After 20 minutes, and until the end of the session, the percentage of beta waves was significantly lower than at baseline. The high frequency component of heart rate variability was significantly lower after 12 minutes of Okinaga and lasted until 23 minutes. The low frequency/high frequency ratio was significantly lower after 18 minutes of Okinaga and until the end of the session. Okinaga produced relaxation, suggesting that deep breathing may relieve anxiety. However, study limitations include potential ambiguity in the interpretation of the low frequency/high frequency ratio, the small sample, and the fact that EEG was measured only on the forehead.

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Extreme prolongation of expiration breathing: Effects on electroencephalogram and autonomic nervous function

Mental Illness ◽

10.4081/mi.2018.7881 ◽

2018 ◽

Vol 10 (2) ◽

Author(s):

Teruhisa Komori

Keyword(s):

High Frequency ◽

Frequency Ratio ◽

Low Frequency ◽

Frequency Component ◽

Small Sample ◽

High Frequency Component ◽

Deep Breathing ◽

Continuous Eeg ◽

Nervous Function ◽

Electrocardiogram Ecg

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APG(Acceleration Plethysmography) Correlate with Moods in Nursing Workers with Fatigue after Work

10.21203/rs.3.rs-177812/v1 ◽

2021 ◽

Author(s):

Miki Ishizuka ◽

Shin-ichiro katsuda ◽

Akihiro Hazama

Keyword(s):

Low Frequency ◽

Frequency Component ◽

Total Power ◽

High Frequency Component ◽

Autonomic Nervous Function ◽

Nursing Stress ◽

Before And After ◽

Nervous Function ◽

Physiological Tests ◽

Normal Work

Abstract Fatigue or stress in the workplace is a serious problem. The profession of nursing, in particular, is physically and mentally stressful, which often leads to job retrenchment, and shortage of workers. Solving this problem requires a deeper understanding of the fatigue and stress caused by work, and there is a need to consider countermeasures. Purpose: The purpose of this study is to assess the correlation between the psychological and physiological fatigue of healthy nurses during normal work, and to measure nursing stress and fatigue more conveniently. Method: We examined healthy nurses’ physiology (Acceleration Plethysmography: APG and Blood Pressure: BP) and psychology (Visual Analogue Scale: VAS and Mood Inventory Scale: MIS) before and after a normal workday. Results: We observed that after a normal days’ work, the nurses’ autonomic activity, high-frequency component power (HF), low-frequency component power/high-component power ratio (LF/HF ratio), and total power (LF་HF) increased significantly. Psychologically, VAS increased significantly, while the MIS Refreshing Mood decreased remarkably. The HF value correlated significantly with VAS and the MIS Refreshing Mood. The MIS Refreshing Mood correlates significantly with increased sympathetic and autonomic nervous function. Thus, an MIS test may alternative for physiological tests to detect fatigue more quickly and easily. Conclusion: These findings may help nurses and other workers reduce fatigue, cope with stress, and prevent illness. We hope this study will contribute towards addressing the issues related to workers’ mental health in the workplace.

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The Tangential Force Affecting the Radial Baffles in a Stirred Vessel: Analysis of the Macro-instability Related Component

Acta Polytechnica ◽

10.14311/450 ◽

2003 ◽

Vol 43 (4) ◽

Author(s):

P. Hasal ◽

I. Fořt ◽

J. Kratěna

Keyword(s):

Experimental Data ◽

Spectral Analysis ◽

Tangential Force ◽

Low Frequency ◽

Frequency Component ◽

Relative Magnitude ◽

Tangential Component ◽

Vertical Position ◽

Total Force ◽

Rushton Turbine

Experimental data obtained by measuring the tangential component of the force affecting radial baffles in a flat-bottomed cylindrical mixing vessel stirred with a Rushton turbine impeller is analysed. Spectral analysis of the experimental data demonstrated the presence of its macro-instability (MI) related low-frequency component embedded in the total force. Two distinct dimensionless frequencies (both directly proportional to the impeller speed of rotation N) of the occurence of the MI component were detected: a lower frequency of approximately 0.025N and a higher frequency of about 0.085N. The relative magnitude QMI of the MI-related component of the total tangential force was evaluated by a combination of proper orthogonal decomposition (POD) and spectral analysis. The values of magnitude QMI varied in the interval [rom approximately 0.05 to 0.30. The magnitude QMI takes maximum values at low Reynolds number values (in laminar and transitional regions). In the turbulent region (ReM >20000) the QMI value is low and practically constant. The dependence oj the QMI values on vertical position in the vessel is only marginal. The results suggest that the magnitude of the MI component of the force is significantly influenced by the liquid viscosity and density.

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Research on Combined Prediction Model for Busy Telephone Traffic

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.610.789 ◽

2014 ◽

Vol 610 ◽

pp. 789-796

Author(s):

Jiang Bao Li ◽

Zhen Hong Jia ◽

Xi Zhong Qin ◽

Lei Sheng ◽

Li Chen

Keyword(s):

Prediction Model ◽

Prediction Accuracy ◽

Low Frequency ◽

Prediction Method ◽

Pso Algorithm ◽

Frequency Component ◽

Least Square ◽

High Frequency Component ◽

Support Vector ◽

Telephone Traffic

In order to improve the prediction accuracy of busy telephone traffic, this study proposes a busy telephone traffic prediction method that combines wavelet transformation and least square support vector machine (lssvm) model which is optimized by particle swarm optimization (pso) algorithm. Firstly, decompose the pretreatment of busy telephone traffic data with mallat algorithm and get low frequency component and high frequency component. Secondly, reconfigure each component and use pso_lssvm model predict each reconfigured one. Then the busy telephone traffic can be achieved. The experimental results show that the prediction model has higher prediction accuracy and stability.

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STORM INDUCED PERIODICITIES OF SUSPENDED SAND MOVEMENT

Coastal Engineering Proceedings ◽

10.9753/icce.v16.105 ◽

1978 ◽

Vol 1 (16) ◽

pp. 105 ◽

Cited By ~ 2

Author(s):

Jay E. Leonard ◽

Benno M. Brenninkmeyer

Keyword(s):

Surf Zone ◽

Normal Wave ◽

Low Frequency ◽

Sediment Concentration ◽

Frequency Component ◽

High Frequency Component ◽

Computational Technique ◽

Electromagnetic Current ◽

Discrete Fourier Analysis ◽

Sediment Movement

An array of electronic sensors was installed on Nauset Light Beach, Cape Cod, Massachusetts, U.S.A., in order to provide a description of the sediment movement during storm conditions. These sensors included two sediment concentration indicators (almometers) which monitor sediment movement as a function of elevation and time, one bidirectional electromagnetic current meter, and a resistive wave staff. Prior field studies performed during "normal" conditions have indicated that surf-zone suspended sediment movement is a low-frequency phenomenon, with the relatively high-frequency component (normal wave period) contributing little to the amount of total sediment transported. Development of a computational technique based upon discrete Fourier analysis and digital filtering called Spectrally Filtered Integration (SFI) provides the calculation and filtering of true units of sediment change in grams-per-liter. Moreover, the SFI technique eliminates the possibility spurious sediment information created by the presence of air bubbles in the water column. Generally, higher-frequency sediment movement is more common during storm conditions than during normal non-storm conditions. This movement is controlled not by the prevailing wave and swell periods, but by a longer period which may be due to water interactions below the surface.

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Secretin effects on gastric functions, hormones and symptoms in functional dyspepsia and health: randomized crossover trial

AJP Gastrointestinal and Liver Physiology ◽

10.1152/ajpgi.00371.2019 ◽

2020 ◽

Vol 318 (4) ◽

pp. G635-G645 ◽

Cited By ~ 2

Author(s):

Justin Brandler ◽

Laurence J. Miller ◽

Xiao Jing Wang ◽

Duane Burton ◽

Irene Busciglio ◽

...

Keyword(s):

Gastric Emptying ◽

Functional Dyspepsia ◽

Animal Studies ◽

Delayed Gastric Emptying ◽

Gastrointestinal Hormones ◽

Receptor Activation ◽

Gastric Accommodation ◽

Double Blind ◽

Secretin Receptor ◽

Therapeutic Mechanism

Abnormal gastric accommodation (GA) and gastric emptying contribute to pathophysiology in functional dyspepsia (FD). Secretin is a key regulator of GA in animal studies. Our aim was to study the effects of secretin on gastric motility, satiation, postprandial symptoms, and key hormones. We performed two double-blind, randomized, saline-controlled crossover trials in 10 healthy volunteers and 10 patients with FD by Rome IV criteria. We used measured GA (by validated SPECT method) after a 111In radiolabeled Ensure 300-mL meal and quantified gastric emptying for 30 min by scintigraphy. Satiation was measured by volume to fullness (VTF) and maximum tolerated volume (MTV) on an Ensure nutrient drink test and postprandial symptoms 30 min post-MTV. Fasting and postprandial GLP-1, GIP, and HPP were measured. The ages and sex distribution of healthy controls and patients with FD were similar. Compared with placebo, secretin delayed gastric emptying at 30 min in both health [−11% (−16, −4), P = 0.004]; and FD [−8% (−9, 0), P = 0.03]. Satiation (VTF and MTV), GA, and plasma levels of GLP-1, GIP, and HPP did not differ between treatment arms in health or FD. On ANCOVA analysis (adjusting for age and sex), secretin did not consistently increase postprandial symptoms in health or FD. Secretin delayed gastric emptying in both health and FD without significantly altering GA, VTF, or MTV or selected hormones. Thus, secretin receptor activation may provide a novel therapeutic mechanism for patients with FD and rapid gastric emptying. NEW & NOTEWORTHY The naturally occurring hormone secretin retards gastric emptying of solids without deleteriously affecting gastric accommodation, satiation, other upper gastrointestinal hormones, or postprandial symptoms. Given these findings, a subset of patients with rapid gastric emptying (e.g., the estimated 20% of patients with functional dyspepsia) could be candidates for treatments that stimulate a secretin receptor such as sacubitril, which inhibits neprilysin, an enzyme that degrades secretin.

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Analysis of the Visual Spectrum of Methyl Orange in Solvents and in Hydrophobic Binding Sites

Canadian Journal of Chemistry ◽

10.1139/v73-095 ◽

1973 ◽

Vol 51 (4) ◽

pp. 628-635 ◽

Cited By ~ 45

Author(s):

Richard L. Reeves ◽

Robert S. Kaiser ◽

Mary S. Maggio ◽

Edward A. Sylvestre ◽

William H. Lawton

Keyword(s):

Hydrogen Bonding ◽

Methyl Orange ◽

Organic Solvents ◽

Absorption Maximum ◽

Low Frequency ◽

Blue Shift ◽

Frequency Component ◽

High Frequency Component ◽

Surfactant Micelle ◽

Aqueous Solvent

The absorption curves of methyl orange (MO) and analogous p-aminophenylazobenzenes in organic and aqueous organic solvents are shown to consist of two severely overlapping bands. The curves have been resolved into two skewed component bands using a regression method. The blue shift of the absorption maximum obtained when organic solvents are added to aqueous solutions of MO, or when MO is bound to bovine serum albumin or a surfactant micelle, is the result of a change in relative intensities of the component bands. The low-frequency component is assigned to a π1 → π1* transition of a solvate in which there is specific hydrogen-bonding interaction between solvent and the azo nitrogens, and the high-frequency component to a π1 → π1* transition of a solvate in which the interaction is absent. The low-frequency component is favored by aqueous solvent compositions and by low temperatures. The free energies of interconversion of the species in various hydrogen-bonding solvents are correlated by the solvent surface tension but not by the dielectric constant. The results show that the shift in absorption maximum accompanying binding to a protein or micelle should be interpreted as a shift in an equilibrium rather than as a shift in transition energy.

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