scholarly journals Primary accessory thyroid carcinoma with negative 99mTcO4− SPECT/CTimaging: a case report and literature review

2019 ◽  
Vol 47 (8) ◽  
pp. 3934-3939
Author(s):  
Yibo Ma ◽  
Feng Qian ◽  
Jianfeng Wang ◽  
Yanping Liu ◽  
Shuiqing Liu
Keyword(s):  
Computed Tomography ◽  
Thyroid Carcinoma ◽  
Single Photon ◽  
Thyroid Cartilage ◽  
Photon Emission ◽  
Thyroid Tissue ◽  
Punch Biopsy ◽  
Pathological Examination ◽  
Emission Computed Tomography ◽  
Accessory Thyroid

Introduction In contrast to orthotopic thyroid carcinoma, primary accessory thyroid carcinoma is very rare. We herein report a case involving primary accessory thyroid carcinoma in a patient with normal ultrasonography of the orthotopic thyroid and negative 99mTcO4− single-photon emission computed tomography (SPECT) scintigraphy. Case presentation: A computed tomography (CT) scan showed soft tissue nodules at the left anterior edge of the thyroid cartilage. To determine whether the mass was accessory thyroid tissue, 99mTcO4− SPECT/CT was performed, and the findings were negative. However, pathological examination after resection showed that mass was a primary accessory thyroid papillary carcinoma. The 1-year follow-up ultrasound showed no lesion at the orthotropic thyroid and neck incision sites. Conclusions This case suggests that negative 99mTcO4− SPECT/CT imaging may not completely exclude the possibility of thyroid carcinoma. A punch biopsy or postoperative pathological examination is necessary for the diagnosis.

Lingual thyroid: diagnosis using a hybrid of single photon emission computed tomography and standard computed tomography

2013 ◽  
Vol 127 (4) ◽  
pp. 432-434 ◽  
Author(s):  
J Dolezal ◽  
J Vizda ◽  
J Horacek ◽  
S Spitalnikova
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Thyroid Tissue ◽  
Ectopic Thyroid ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Emission Computed ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

AbstractAim:To present a rare case of lingual thyroid detected using a hybrid of single photon emission computed tomography and standard computed tomography in a young woman with hypothyroidism.Materials and methods:A 29-year-old woman was screened for autoimmune thyroid disorders in early pregnancy, and found to have subclinical hypothyroidism. No thyroid tissue was found in the anterior neck upon ultrasonography, raising suspicions of an ectopic thyroid. The patient was treated with levothyroxine throughout the remainder of her pregnancy, and developed postpartum thyroiditis requiring an increase in levothyroxine dosage. Whole-body scintigraphy and zoomed static head and neck scintigraphy were performed. Abnormal 99mTc-pertechnetate uptake was observed in the oral region, whereas no uptake was found in the usual thyroid location. Hybrid imaging using single photon emission computed tomography and standard computed tomography was performed to improve three-dimensional representation of the area of increased activity.Results:The latter imaging modality detected ectopic thyroid tissue in the tongue.Conclusion:Whole body 99mTc-pertechnetate scintigraphy and a hybrid of single photon emission computed tomography and standard computed tomography are effective imaging modalities for the investigation of ectopic thyroid tissue. The latter modality is particularly recommended, as it allows more precise spatial visualisation of increased isotope uptake activity in the head and neck.

scholarly journals The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case

2021 ◽  
Vol 1 (21) ◽  
Author(s):  
Seonah Choi ◽  
JaeSang Ko ◽  
Se Hoon Kim ◽  
Eui Hyun Kim
Keyword(s):  
Computed Tomography ◽  
Cavernous Hemangioma ◽  
Single Photon ◽  
Smooth Muscle Actin ◽  
Photon Emission ◽  
Pathological Examination ◽  
Emission Computed Tomography ◽  
Illustrative Case ◽  
Endoscopic Endonasal ◽  
Cavernous Hemangiomas

BACKGROUND Orbital angioleiomyoma is generally considered a rare tumor; approximately 40 cases have been reported. However, after their experience with 6 consecutive cases in their single institution during 3 years, the authors speculate that the incidence of orbital angioleiomyomas is possibly underestimated. OBSERVATIONS A 34-year-old female presented with progressive exophthalmos of 2 years’ duration. Orbital computed tomography and magnetic resonance imaging revealed a well-circumscribed orbital tumor with partial and heterogeneous gadolinium enhancement. Technetium-99m red blood cell single-photon emission computed tomography showed positive perfusion in the late blood-pool phase, which was exactly consistent with the finding of a cavernous hemangioma. Under the impression of a cavernous hemangioma, the authors accessed the mass with an endoscopic endonasal approach and completely removed it without neurological deficit. Pathological examination revealed that the final diagnosis was an angioleiomyoma with positive immunostaining results for smooth muscle actin (SMA). LESSONS The incidence of orbital angioleiomyomas may not be very low, as these lesions have possibly been misdiagnosed as orbital cavernous hemangiomas because of their histological similarity. Preoperative presumption and differentiation from cavernous hemangiomas are very challenging because of the rarity of orbital angioleiomyoma and similar radiological findings. SMA immunostaining may be critical to differentiate orbital angioleiomyomas from cavernous hemangiomas.

The Value of 99mTc-MIBI SPECT/CT in the Postoperative Assessment of Patients with Differentiated Thyroid Carcinoma

2021 ◽  
Vol 17 ◽  
Author(s):  
Berna Okudan ◽  
Bedri Seven ◽  
Nedim C.M. Gülaldı ◽  
Mustafa Çapraz ◽  
Yusuf Açıkgöz
Keyword(s):  
Computed Tomography ◽  
Thyroid Carcinoma ◽  
Single Photon ◽  
Lung Metastases ◽  
Photon Emission ◽  
Differentiated Thyroid Carcinoma ◽  
Whole Body ◽  
Emission Computed Tomography ◽  
99Mtc Mibi ◽  
Mibi Spect

Background: The therapeutic approaches of differentiated thyroid carcinoma (DTC) are surgery, ablation therapy with the postoperative use of radioiodine-131 (131I), and thyroid-stimulating hormone (TSH) suppression therapy. After the surgical therapy, the patient should be assessed for remnants/metastases. Objective: The purpose of this research was to investigate the role of technetium-99m-methoxyisobutylisonitrile (99mTc-MIBI) single photon emission computed tomography/computed tomography (SPECT/CT) in the postoperative management of patients with DTC. Methods: The study comprised 22 DTC patients (13 women, 9 men; mean age 46.55 ± 13.27 y) who underwent a total thyroidectomy previously. All patients were investigated for thyroid remnants/metastases by 99mTc-MIBI SPECT/CT, posttherapy 131I whole-body scan (WBS) and ultrasound (US). Serum TSH, thyroglobulin and anti-Tg antibody levels were measured. Results of imaging modalities and laboratory measurements were compared with each other. Results: 99mTc-MIBI SPECT/CT, 131I WBS and US respectively demonstrated thyroid remnants in 15 (68.18%), 22 (100%) and 14 (63.63%) of the all patients and metastatic lymph nodes in 8 (100%), 6 (75%) and 6 (75%) of the 8 patients with lymph node metastases. 99mTc-MIBI SPECT/CT also demonstrated lung metastases in 2 patients (9.09% of all patients). The same result was obtained with 131I WBS. Conclusion : The findings of this study show that 99mTc-MIBI SPECT/CT can be effective for detecting metastases in patients with DTC who underwent surgery prior to 131I therapy.

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