scholarly journals Multiple extracranial metastases from glioblastoma multiforme: a case report and literature review

2020 ◽  
Vol 48 (6) ◽  
pp. 030006052093045 ◽  
Author(s):  
Jing Liu ◽  
Liangfang Shen ◽  
Guyu Tang ◽  
Siyuan Tang ◽  
Weilu Kuang ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Pulmonary Metastases ◽  
Brain Magnetic Resonance Imaging ◽  
Salvage Chemotherapy ◽  
Intracranial Tumor ◽  
Extracranial Metastasis ◽  
Resonance Imaging ◽  
Extracranial Metastases ◽  
Intracranial Recurrence

Extracranial metastasis from glioblastoma multiforme (GBM) is rare, especially multi-site metastases without intracranial recurrence. However, the metastatic mechanism of GBM remains unknown and there is currently no consensus regarding the best therapeutic regimen. We report the case of a 46-year-old man with primary GBM who developed scalp metastases and subsequent multiple pulmonary metastases. He was treated with the Stupp regimen after surgery for the intracranial tumor. However, a series of soft masses in the scalp were subsequently identified, and new nodules were found in his left eyebrow arch during chemoradiotherapy. Despite salvage chemotherapy and targeted therapy, the patient eventually died of respiratory failure with multiple pulmonary metastases. This case highlights the need for rigorous follow-up, including brain magnetic resonance imaging, in patients with GBM. The occurrence of extra-central nervous system symptoms indicates the possibility of metastasis, and the relevant examinations should be conducted promptly. Positive therapies may help to relieve symptoms and prolong survival in patients with metastatic GBM.

Changes in the corticospinal tract after wearing prosthesis in bilateral transtibial amputation

2017 ◽  
Vol 41 (5) ◽  
pp. 507-511
Author(s):  
Sang Yoon Lee ◽  
Si Hyun Kang ◽  
Don-Kyu Kim ◽  
Kyung Mook Seo ◽  
Hee Joon Ro ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Diffusion Tensor Imaging ◽  
Magnetic Resonance ◽  
Primary Motor Cortex ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Brain Magnetic Resonance Imaging ◽  
Resonance Imaging ◽  
Transtibial Amputation

Background:After amputation, the brain is known to be reorganized especially in the primary motor cortex. We report a case to show changes in the corticospinal tract in a patient with serial bilateral transtibial amputations using diffusion tensor imaging.Case Description and Methods:A 78-year-old man had a transtibial amputation on his left side in 2008 and he underwent a right transtibial amputation in 2011. An initial brain magnetic resonance imaging with a diffusion tensor imaging was performed before starting rehabilitation on his right transtibial prosthesis, and a follow-up magnetic resonance imaging with diffusion tensor imaging was performed 2 years after this.Findings and Outcomes:In the initial diffusion tensor imaging, the number of fiber lines in his right corticospinal tract was larger than that in his left corticospinal tract. At follow-up diffusion tensor imaging, there was no definite difference in the number of fiber lines between both corticospinal tracts.Conclusion:We found that side-to-side corticospinal tract differences were equalized after using bilateral prostheses.Clinical relevanceThis case report suggests that diffusion tensor imaging tractography could be a useful method to understand corticomotor reorganization after using prosthesis in transtibial amputation.

Can unenhanced brain magnetic resonance imaging be used in routine follow up of meningiomas to avoid gadolinium deposition in brain?

2019 ◽  
Vol 53 ◽  
pp. 155-161
Author(s):  
Feride Kural Rahatli ◽  
Fuldem Yildirim Donmez ◽  
Cagri Kesim ◽  
Kemal Murat Haberal ◽  
Hale Turnaoglu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brain Magnetic Resonance Imaging ◽  
Resonance Imaging ◽  
Gadolinium Deposition

scholarly journals A case report of an immunocompetent patient with Coccidioides meningoencephalitis with atypical brain magnetic resonance imaging findings during a 1 year follow-up

2019 ◽  
Vol 7 (28) ◽  
pp. 33-37
Author(s):  
Dongkwan Jin ◽  
Juliana Gomez
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Image ◽  
Brain Magnetic Resonance Imaging ◽  
Immunocompetent Patient ◽  
Antifungal Drugs ◽  
Resonance Imaging ◽  
Meningeal Enhancement ◽  
Brain Magnetic Resonance Image ◽  
One Year

Coccidioides meningoencephalitis is a central nervous system (CNS) fungal infection withCoccidioides species which can lead to various CNS complications, such as hydrocephalus,vasculitis, and stroke. Most cases reported with Coccidioides meningoencephalitis were inimmunocompromised patients, and the radiologic characteristics on this condition are not wellestablished. Here we report a case of Coccidioides meningoencephalitis in an immunocompetentpatient with one-year follow-up brain magnetic resonance image (MRI) studies after successfultreatment with antifungal drugs. The MRI demonstrated subcortical parenchymal lesions,selectively involving the white matter, and persistent meningeal enhancement.

scholarly journals Bilateral Striatal Necrosis after Sydenham's Chorea in a 7-Year-Old Boy: A 2-Year Follow-Up

2018 ◽  
Vol 49 (03) ◽  
pp. 209-212 ◽  
Author(s):  
C. Canavese ◽  
M. Casabianca ◽  
C. Olivieri ◽  
S. Mancini ◽  
G. Migliore ◽  
...  
Keyword(s):  
Group A Streptococcus ◽  
Brain Magnetic Resonance Imaging ◽  
School Age ◽  
Resonance Imaging ◽  
Sydenham’S Chorea ◽  
Group A ◽  
Sydenham's Chorea ◽  
Infancy And Early Childhood ◽  
Striatal Necrosis

AbstractChild bilateral striatal necrosis (BSN) is a rare and etiologically heterogeneous condition. An association with group A streptococcus (GAS) infection was previously reported in two cases of BSN in infancy and early childhood. We here report on a 7-year-old boy who developed chorea and dystonia 20 days after symptomatic recovery from Sydenham's chorea. Repeated brain magnetic resonance imaging scans, obtained before, soon after the onset of the post-Sydenham symptoms, and 1 year later were consistent with an evolution from bilateral striatal microbleeding to necrosis, and consequently reduced basal ganglia volume and enlargement of the frontal horns. No support was found for other possible autoimmune, infectious, metabolic, toxic or genetic etiologies for BSN. Prednisone treatment was instituted and continued for 1 year. Two years after the onset of the post-Sydenham symptoms, the child, although much improved, still has generalized dystonic–choreic movements. This case confirms and extends into school age, the link between GAS and BSN.

scholarly journals Ventricular Repolarization is Associated with Cognitive Function, but Not with Cognitive Decline and Brain Magnetic Resonance Imaging (MRI) Measurements in Older Adults

2020 ◽  
Vol 9 (4) ◽  
pp. 911
Author(s):  
Michelle H. Zonneveld ◽  
Raymond Noordam ◽  
Jeroen van der Grond ◽  
Behnam Sabayan ◽  
Simon P. Mooijaart ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cognitive Function ◽  
Brain Magnetic Resonance Imaging ◽  
Older Individuals ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Measurements

We aimed to investigate the cross-sectional and longitudinal associations of electrocardiogram (ECG)-based QT, QTc, JT, JTc, and QRS intervals with cognitive function and brain magnetic resonance imaging (MRI) measurements in a cohort of older individuals at increased risk for cardiovascular disease, but free of known arrhythmias. We studied 4627 participants (54% female, mean age 75 years) enrolled in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Ten-second ECGs were conducted at baseline. Cognitive function was tested at baseline and repeated during a mean follow-up time of 3.2 years. Structural MRIs were conducted in a subgroup of 535 participants. Analyses were performed with multivariable (repeated) linear regression models and adjusted for cardiovascular risk-factors, co-morbidities, and cardiovascular drug use. At baseline, longer QT, JT, JTc—but not QTc and QRS intervals—were associated with a worse cognitive performance. Most notably, on the Stroop Test, participants performed 3.02 (95% CI 0.31; 5.73) seconds worse per standard deviation higher QT interval, independent of cardiovascular risk factors and medication use. There was no association between longer ventricular de- or repolarization and structural brain measurements. Therefore, specifically ventricular repolarization was associated with worse cognitive performance in older individuals at baseline but not during follow-up.

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