The Addition of Oxprenolol to Hypertensive Patients Treated with Methyldopa – A General Practice Study

1974 ◽  
Vol 2 (1) ◽  
pp. 1-6 ◽  
Author(s):  
J E Murphy ◽  
Susan M Standen ◽  
W A Forrest
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
Subsequent Reduction ◽  
Hypertensive Patients ◽  
Practice Study

In eighty-seven hypertensive patients in general practice, treated with either methyldopa or the combination of methyldopa and a diuretic, oxprenolol 80 mg was added to the regime with subsequent reduction in methyldopa dosage. In the two groups of patients studied, those whose blood pressure was ‘well controlled’ and another group with a higher blood pressure, the control of blood pressure levels was improved and the incidence of reported tiredness decreased.

A Multicentre Study of a Once Daily Dosage of Acebutolol* in the Treatment of Hypertension in General Practice

1979 ◽  
Vol 7 (3) ◽  
pp. 201-214 ◽  
Author(s):  
P G Baker ◽  
J Goulton
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
Adverse Reactions ◽  
Multicentre Trial ◽  
Pressure Control ◽  
Morning Dose ◽  
Progressive Reduction ◽  
Once Daily ◽  
Hypertensive Patients ◽  
Treatment Of Hypertension

A three-month open, multicentre trial was carried out in 2132 hypertensive patients under uncontrolled conditions in general practice, to assess the effectiveness and tolerance of acebutolol when given orally as a single morning dose, in the range of 200 to 1200 mg/day. Concomitant antihypertensive therapy was given to 702 patients. Forty-five patients, out of 1893 who were eligible for analysis, showed inadequate blood pressure control and were withdrawn from the study. There were 602 reports of side-effects or adverse reactions attributed to acebutolol in 584 patients, necessitating 120 withdrawals from the trial. The results showed that acebutolol given once daily produces a substantial and progressive reduction in blood pressure over the three months of the trial. The changes from pre-trial values of all haemodynamic assessments measured were statistically significant (p < 0-001).

Oxprenolol in Hypertension: A Report on 187 Patients in General Practice Originally Treated with Clonidine

1975 ◽  
Vol 3 (6) ◽  
pp. 395-398 ◽  
Author(s):  
W A Forrest
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
Side Effects ◽  
Receptor Antagonist ◽  
Systolic Pressure ◽  
Hypertensive Patients ◽  
Β Receptor

Substitution, in part or totally, of the β- receptor antagonist, oxprenolol, for clonidine in 187 hypertensive patients resulted in significant reduction in blood pressure levels, particularly of systolic pressure. The incidence of unwanted side-effects was markedly reduced, with an accompanying improvement in the quality of the patient's life.

scholarly journals Multimorbidity and Blood Pressure Control in 37 651 Hypertensive Patients From Danish General Practice

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Maja S. Paulsen ◽  
Morten Andersen ◽  
Janus L. Thomsen ◽  
Henrik Schroll ◽  
Pia V. Larsen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Hypertensive Patients

Blood Pressure Levels in Treated Hypertensive Patients in General Practice in Norway

2001 ◽  
Vol 10 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Arne Westheim ◽  
Trine Klemetsrud ◽  
Steinar Tretli ◽  
Hans Petter Stokke ◽  
Harald Olsen
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
Hypertensive Patients

scholarly journals Hypertension management in general practice

1997 ◽  
Vol 90 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Michael Whitfield ◽  
Anthony Hughes
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
General Practice ◽  
Drug Treatment ◽  
General Practitioners ◽  
Cardiovascular Events ◽  
Postal Questionnaire ◽  
Hypertension Management ◽  
Hypertensive Patients ◽  
Unrealistic Expectations

The views of 542 general practitioners (GPs) and 64 consultant physicians about the management of patients with hypertension in general practice were sought by postal questionnaire. 325 (60%) of the GPs and 45 (70%) of the consultant physicians completed the questionnaire. For a 40-year-old man with no other cardiovascular risk factors most general practitioners would intervene with drugs at blood pressure levels specified in published guidelines, whereas many local consultants and older GPs would consider drug treatment at lower levels. About 75% of GPs, compared with 87% of consultants, would suggest drug treatment in a woman of 70 years with a BP of 180/ 100 mmHg. Although consultants tended to expect GPs to order more tests when investigating a patient with hypertension than the GPs actually did, both GPs and consultants would order similar types of investigations apart from imaging. Consultants had different expectations about the frequency with which general practitioners should record patients' blood pressure and the GPs' ability to prevent cardiovascular events in hypertensive patients. Many older GPs and consultants seem to have unrealistic expectations of the value of treating patients with hypertension.

Oxprenolol in Hypertension. A Report on 2,770 Patients in General Practice Originally Treated with Methyldopa

1976 ◽  
Vol 21 (1) ◽  
pp. 28-30 ◽  
Author(s):  
W. A. Forrest
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
Receptor Antagonist ◽  
Considerable Improvement ◽  
Hypertensive Patients ◽  
Β Receptor

Substitution, in part or totally, of the non-selective β-receptor antagonist oxprenolol for methyldopa in 2,770 treated hypertensive patients resulted in a significant reduction in blood pressure levels and a considerable improvement in the quality of the patient's life.

Multicentre General Practitioner Assessment of ‘Tenormin’ and Methyldopa

1979 ◽  
Vol 7 (4) ◽  
pp. 324-327
Author(s):  
J A Tweed ◽  
B Mason ◽  
R Sleigh
Keyword(s):  
Blood Pressure ◽  
General Practice ◽  
General Practitioner ◽  
Side Effects ◽  
Large Scale ◽  
Pressure Control ◽  
Hypertensive Patients ◽  
Relative Lack ◽  
Dosage Regime ◽  
Set Up

A large scale study in general practice was set up to investigate the effects, of transferring hypertensive patients from treatment with usually less than 1 g daily of methyldopa to atenolol ('Tenormin') 100 mg daily. The results demonstrate an improvement in blood pressure control with atenolol treatment and a reduction in the incidence of side-effects. The simple dosage regime, combined with proven effectiveness and a relative lack of side-effects makes atenolol a useful treatment for the hypertensive patient.

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