Analysis of 100 Cases of Paget's Disease of the Breast

1976 ◽  
Vol 62 (5) ◽  
pp. 529-535 ◽  
Author(s):  
Bruno Salvadori ◽  
Giuseppe Fariselli ◽  
Roberto Saccozzi
Keyword(s):  
Surgical Treatment ◽  
Median Survival ◽  
National Cancer Institute ◽  
Survival Rates ◽  
Paget’S Disease ◽  
Radical Mastectomy ◽  
Paget's Disease ◽  
Extended Radical Mastectomy ◽  
Extent Of Surgery ◽  
Palpable Nodule

Of 100 cases of Paget's disease of the breast admitted to the National Cancer Institute of Milan from 1940 to 1974, 91 were statistically evaluated. They were divided in two groups according to presence or absence of a palpable nodule. The results of surgical treatment in terms of 5 and 10 year survival rates were 59 and 44 %, respectively, with a median survival of 9 years. For the two separate subgroups, those with a palpable nodule were 38 and 22 % for 5 and 10 years, respectively, while those without a palpable nodule were 92 and 82 % for 5 and 10 years, respectively. For the two groups the median survival was 3.6 and 16.4 years, respectively. The extent of surgery should be dependent on the presence or absence of palpable nodules under the nipple. For the two groups (with and without) extended radical mastectomy and the Patey-Dawson mastectomy are recommended.

Thirty Year Old Female Presented with Nipple Destruction: A Case Report

2019 ◽  
Vol 11 (1) ◽  
pp. 81-83
Author(s):  
Md Mustafizur Rahman ◽  
Nadim Ahmed ◽  
Sami Ahmad ◽  
Shoaeb Imtiaz Alam ◽  
Mohammad Rashedul Hassan ◽  
...  
Keyword(s):  
Invasive Carcinoma ◽  
Paget’S Disease ◽  
Radical Mastectomy ◽  
Paget's Disease ◽  
College Hospital ◽  
Rare Type ◽  
Medical College ◽  
Ductal Cell ◽  
Areola Complex

Paget’s disease of the breast is a rare type of cancer of the nipple–areola complex and that is often associated with an underlying in situ or invasive carcinoma. It is often misdiagnosed as eczema of breast and treatment is delayed. Here we present a case where a 30 year old female presented with itching ulceration and destruction of her left nipple. She was treated initially by local physicians by applying local ointments but as her condition did not improve she was admitted to department of surgery Shaheed Suhrawardy Medical College hospital where she was diagnosed as Paget’s disease with infiltrating ductal cell carcinoma. She underwent modified radical mastectomy with axillary clearance and referred to oncology department for further management. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 81-83

Extended Radical Mastectomy with Removal of Axillary, Internal Mammary, Supraclavicular and Mediastinal Lymph Nodes

1969 ◽  
Vol 55 (6) ◽  
pp. 413-416 ◽  
Author(s):  
Umberto Veronesi ◽  
Lorenzo Zingo
Keyword(s):  
Lymph Nodes ◽  
National Cancer Institute ◽  
Radical Mastectomy ◽  
Mediastinal Lymph Nodes ◽  
Extended Radical Mastectomy ◽  
Internal Mammary

Description of the technique of super-radical mastectomy with removal of axillary, internal mammary, supraclavicular and mediastinal lymph nodes developed at the National Cancer Institute of Milan and previously reported (1). The thoracic defect due to thoracectomy with removal of the clavicle, the medial portion of the first and second ribs and the corresponding half of the sternum is now avoided by sternal replacement and suture. Thus radicality is maintained and cosmetic impairment is confined to breast removal.

Surgical treatment in spine Paget’s disease: a systematic review

2015 ◽  
Vol 26 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Alberto Jorge-Mora ◽  
Samer Amhaz-Escanlar ◽  
Ana Lois-Iglesias ◽  
Susana Leborans-Eiris ◽  
Jesús Pino-Minguez
Keyword(s):  
Systematic Review ◽  
Surgical Treatment ◽  
Paget’S Disease ◽  
Paget's Disease

Photodynamic therapy with M-ALA as non surgical treatment option in patients with primary extramammary Paget's disease

2013 ◽  
Vol 130 (1) ◽  
pp. 90-94 ◽  
Author(s):  
Rosanna Fontanelli ◽  
Andrea Papadia ◽  
Fabio Martinelli ◽  
Domenica Lorusso ◽  
Barbara Grijuela ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Surgical Treatment ◽  
Treatment Option ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Non Surgical Treatment ◽  
Extramammary Paget's Disease

scholarly journals Paget’s disease of the breast: a case series

2020 ◽  
Vol 7 (8) ◽  
pp. 2706
Author(s):  
Solomon N. Elenwo ◽  
Rollings S. Jamabo
Keyword(s):  
Invasive Carcinoma ◽  
Paget’S Disease ◽  
Case Series ◽  
Radical Mastectomy ◽  
Paget's Disease ◽  
Histological Findings ◽  
Modified Radical Mastectomy ◽  
Modes Of Presentation ◽  
Simple Mastectomy

Paget’s disease of the nipple is a rare disease with a rather bizarre presentation which makes the diagnosis easily missed. Three cases are presented here with different modes of presentation and histological findings. A biopsy provided the definitive diagnosis in the three patients and the treatments offered was based on the histological findings - modified radical mastectomy and simple mastectomy for invasive carcinoma and carcinoma in-situ respectively.

The Surgical Treatment of Female Genital Paget's Disease.

1996 ◽  
Vol 58 (1) ◽  
pp. 94-97 ◽  
Author(s):  
Yasumasa IWASAKI ◽  
Tamotsu MORI ◽  
Yoshihiro MIYAMOTO ◽  
Yuji HATANO ◽  
Shoso YAMAMOTO
Keyword(s):  
Surgical Treatment ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Female Genital

Perianal Paget's Disease

2006 ◽  
Vol 10 (4) ◽  
pp. 197-200 ◽  
Author(s):  
Zion Zibly ◽  
Josefh Haik ◽  
Marat Khaikin ◽  
Iris Barshack ◽  
Oded Zmora
Keyword(s):  
Surgical Treatment ◽  
Early Diagnosis ◽  
Clinical Management ◽  
Paget’S Disease ◽  
External Genitalia ◽  
Paget's Disease ◽  
Perianal Region ◽  
Apocrine Glands ◽  
High Index Of Suspicion ◽  
Female External Genitalia

Background: Perianal Pa get's disease is an uncommon intraepithelial neoplasm that involves areas affluent with apocrine glands, most frequently in the female external genitalia, but may also affect the perianal region. Objective: We present the pathologic and clinical management of a case of Paget's disease involving the perianal region, in which diagnosis was delayed for 8 years. Conclusions: The importance of a high index of suspicion for early diagnosis is emphasized, which should be followed by aggressive surgical treatment with wide excision and local reconstruction.

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