Alien hand syndrome and migraine with aura: A case report

Cephalalgia ◽  
2018 ◽  
Vol 38 (13) ◽  
pp. 1984-1987 ◽  
Author(s):  
Yuksel Erdal ◽  
Ufuk Emre ◽  
Arife Cimen Atalar ◽  
Taskın Gunes

Background Alien Hand Syndrome (AHS) is an uncontrollable, involuntary, but in appearance, purposeful motor control disorder of the upper extremity. Case report A 42-year-old male patient was admitted to our clinic complaining of involuntary motor activity in his right hand. He had a previous history of migraine with visual aura. The uncontrollable motor control disorder was compatible with Alien Hand Syndrome, which was appearing immediately after the visual aura and before the beginning of headache. Conclusion Alien Hand Syndrome is usually observed with anterior cerebral artery infarction, midline tumors, trauma and several neurodegenerative diseases, but is rarely seen in paroxysmal conditions such as migraine with aura.

Author(s):  
Bárbara Costa ◽  
Felipe Carvalho ◽  
Gabriel Kubota ◽  
Daniel Andrade ◽  
Ida Fortini

IntroductionCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most frequent hereditary cause of brain ischemic small vessel disease (1). Migraine with aura (MA) is typically the presenting and most common clinical feature of CADASIL. The estimated prevalence of MA in CADASIL ranges from 20 to 40% (2).Case Report43-year-old woman, with previous history of hypertension, diabetes, and episodic migraine with visual aura, suffered three episodes of hemihyposthesia in 2016, 2017 and 2018 (one on her right and the other two on her left). In the last of these episodes, she reported worsening of the visual acuity of her right eye, and developed chronic migraine. Brain MRI showed extensive areas of confluent T2 hyperintensity in the white matter, as well as in the nucleocapsular and bilateral thalamic regions. In all three episodes the patient was treated with IV or oral corticosteroids and had partial improvement of the symptoms. The patient had familiar history of relatives who had suffered multiple strokes.DiscussionThe diagnosis of multiple sclerosis was firstly considered due to the evolution in clinical attacks and the response to corticotherapy. However, the patient’s family history, MRI findings and previous diagnosis of migraine with visual aurea lead to the suspicion of CADASIL. This diagnosis was ultimately confirmed through genetic testing that showed C> T variation in NOTCH3 gene. Migraine was successfully treated with greater occipital nerve blocks and topiramate.Final CommentCADASIL stroke-like attacks remain a therapeutic challenge. It is possible that corticosteroid treatment may benefit these patients by reducing the inflammatory process that results from blood-brain barrier breakdown. More studies are needed to evaluate the efficacy and safety of corticotherapy in this population.


VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.


Ergonomics ◽  
2003 ◽  
Vol 46 (7) ◽  
pp. 731-746 ◽  
Author(s):  
Stuart McGill ◽  
Sylvain Grenier ◽  
Melanie Bluhm ◽  
Richard Preuss ◽  
Susan Brown ◽  
...  

Author(s):  
David Mackarel ◽  
Sowmy Murickal ◽  
Farah Kassim ◽  
Helen Banks ◽  
Shagufay Mahendran ◽  
...  

PM&R ◽  
2018 ◽  
Vol 10 ◽  
pp. S94-S95
Author(s):  
Martin D. Weaver ◽  
Gemayaret Alvarez-Gonzalez

2020 ◽  
Vol 11 ◽  
Author(s):  
Sabina Cenciarelli ◽  
Valeria Calbi ◽  
Federica Barzaghi ◽  
Maria Ester Bernardo ◽  
Chiara Oltolini ◽  
...  

In this work we present the case of SARS-CoV-2 infection in a 1.5-year-old boy affected by severe Wiskott-Aldrich Syndrome with previous history of autoinflammatory disease, occurring 5 months after treatment with gene therapy. Before SARS-CoV-2 infection, the patient had obtained engraftment of gene corrected cells, resulting in WASP expression restoration and early immune reconstitution. The patient produced specific immunoglobulins to SARS-CoV-2 at high titer with neutralizing capacity and experienced a mild course of infection, with limited inflammatory complications, despite pre-gene therapy clinical phenotype.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Aaron J. Roberto ◽  
Subhash Pinnaka ◽  
Abhishek Mohan ◽  
Hiejin Yoon ◽  
Kyle A. B. Lapidus

Catatonia is especially concerning in children and adolescents. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of neuroleptic medication or psychotic symptoms, presenting with first-episode catatonia in the presence of disorganized, psychotic thoughts. We then review the catatonia syndrome, citing examples in the literature supporting its underdiagnosis in children and adolescents, and discuss successful treatment modalities. It is important to diagnose and treat catatonia as efficiently as possible, to limit functional and emotional distress to the patient.


2014 ◽  
Vol 338 (1-2) ◽  
pp. 203-206 ◽  
Author(s):  
Dennis A. Nowak ◽  
Kathrin Bösl ◽  
Jitka Lüdemann-Podubecka ◽  
Hans-Jürgen Gdynia ◽  
Matthias Ponfick

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