scholarly journals Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report

2020 ◽  
Vol 11 ◽  
Author(s):  
Sabina Cenciarelli ◽  
Valeria Calbi ◽  
Federica Barzaghi ◽  
Maria Ester Bernardo ◽  
Chiara Oltolini ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Case Report ◽  
Immune Reconstitution ◽  
Autoinflammatory Disease ◽  
Clinical Phenotype ◽  
High Titer ◽  
Previous History ◽  
Wiskott Aldrich Syndrome ◽  
Neutralizing Capacity ◽  
History Of

In this work we present the case of SARS-CoV-2 infection in a 1.5-year-old boy affected by severe Wiskott-Aldrich Syndrome with previous history of autoinflammatory disease, occurring 5 months after treatment with gene therapy. Before SARS-CoV-2 infection, the patient had obtained engraftment of gene corrected cells, resulting in WASP expression restoration and early immune reconstitution. The patient produced specific immunoglobulins to SARS-CoV-2 at high titer with neutralizing capacity and experienced a mild course of infection, with limited inflammatory complications, despite pre-gene therapy clinical phenotype.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

scholarly journals Adolescent Catatonia Successfully Treated with Lorazepam and Aripiprazole

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Aaron J. Roberto ◽  
Subhash Pinnaka ◽  
Abhishek Mohan ◽  
Hiejin Yoon ◽  
Kyle A. B. Lapidus
Keyword(s):  
Case Report ◽  
Children And Adolescents ◽  
Emotional Distress ◽  
Successful Treatment ◽  
Previous History ◽  
Treatment Modalities ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Significant Impairment ◽  
History Of

Catatonia is especially concerning in children and adolescents. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of neuroleptic medication or psychotic symptoms, presenting with first-episode catatonia in the presence of disorganized, psychotic thoughts. We then review the catatonia syndrome, citing examples in the literature supporting its underdiagnosis in children and adolescents, and discuss successful treatment modalities. It is important to diagnose and treat catatonia as efficiently as possible, to limit functional and emotional distress to the patient.

scholarly journals Ultrasound Therapy in the Treatment of Plantar Wart: A Case Study

2021 ◽  
Vol SP (1) ◽  
Author(s):  
Poonam Dhankher ◽  
Sakshi ◽  
Dimple Choudhry
Keyword(s):  
Case Report ◽  
Weight Bearing ◽  
Previous History ◽  
Skin Condition ◽  
Papilloma Virus ◽  
Plantar Wart ◽  
Plantar Surface ◽  
History Of ◽  
Plantar Warts

Verucae or plantar warts is a painful skin condition that demonstrates a high resistance to various treatments. They can be caused by trauma or human papilloma virus. The infection is mostly caused by a breach in the skin. The virus is usually contacted by walking barefoot in community swimming pool areas. The condition is common in sports persons. Our research focused on warts that occur on plantar surface of foot also known as plantar warts. They result in pain with pressure on weight bearing surfaces so walking is difficult and painful. Risk factors include using community showers barefoot, previous history of warts and decreased immune function. Case Report: We present a case report of a female aged 24 years who was clinically diagnosed with plantar wart. She developed recurrent plantar warts. For a year she was treated with pairing and punch excision with no success. Then ultrasound program was initiated with dosage of 0.6 watt /cm2 and increased up to 1 watt/cm2 for 15 min given at 1-week interval for 15 weeks. At the end of 15th week, the plantar wart had completely disappeared.

scholarly journals Unsolved Mystery of Synchronous Metastatic Adenocarcinoma and Echinococcus Cystic Infection, a Major Break Through in Clinical Oncology: A Case Report

2020 ◽  
Author(s):  
Aamer Ubaid ◽  
Farishta Waheed ◽  
Awais Naeem
Keyword(s):  
Case Report ◽  
Immune System ◽  
Previous History ◽  
Unknown Primary ◽  
Metastatic Adenocarcinoma ◽  
Zoonotic Infection ◽  
Cestode Species ◽  
Major Break ◽  
History Of

Echinococcus cystic infection is a zoonotic infection caused by the larval stage of cestode species belonging to the genus Echinococcus. Through the modulation of the immune system by this parasite, there is an established link of this infection with the metastasis and progression of a tumor. We present a case of a patient with synchronous findings of metastatic adenocarcinoma with unknown primary along with the previous history of echinococcal infection, which highlights the need for prompt management of such infections with a regular follow up of such patients.

scholarly journals Thyrotoxic periodic paralysis in new-onset hyperthyroidism – a case report and review of the literature

2014 ◽  
Vol 12 (4) ◽  
pp. 531
Author(s):  
Joaquim Custódio da Silva Junior ◽  
Helton Estrela Ramos
Keyword(s):  
Case Report ◽  
Previous History ◽  
Rare Condition ◽  
Periodic Paralysis ◽  
Emergency Physicians ◽  
Review Of The Literature ◽  
Font Size ◽  
Thyrotoxic Periodic Paralysis ◽  
History Of ◽  
New Onset

<p class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: justify;"><em><span style="font-size: 10.0pt; font-family: ";Times New Roman";,";serif";; mso-ansi-language: EN-US;" lang="EN-US">Thyrotoxic periodic paralysis (TPP) is a rare condition related to hyperthyroidism, with specific clinical and physiopathological features. In this article, we discuss a case report of a patient that develops TPP with no previous history of thyroid illness, highlighting semiological characteristics that can help Emergency physicians to suspect of this condition. Subsequently, we review the recent articles about TPP, with focus in the molecular basis of ion channelopathies and predisposing factors, and discuss the therapeutic approach at acute phase of TPP and prevention of crisis recurrence.</span></em></p>

scholarly journals Surgical, Orthodontic and Prosthodontic Rehabilitation of a Patient with Follicular Ameloblastoma: A Case Report

2010 ◽  
Vol 04 (02) ◽  
pp. 192-196 ◽  
Author(s):  
Herman F. Sailer ◽  
Fadi Tarawneh ◽  
Panagiotis Fourkas ◽  
Dimitrios Z. Antoniades ◽  
Athanasios E. Athanasiou
Keyword(s):  
Case Report ◽  
Bone Graft ◽  
Female Patient ◽  
Adult Female ◽  
Orthodontic Treatment ◽  
Previous History ◽  
Calvarial Bone ◽  
History Of ◽  
Sufficient Space ◽  
Adult Female Patient

This case report describes the combined surgical, orthodontic and prosthodontic rehabilitation of an adult female patient with a previous history of follicular ameloblastoma, which was treated through partial mandibulectomy and an immediate replacement of missing bone with an autologous calvarial bone graft. Orthodontic treatment was undertaken in order to restore occlusal disturbances and obtain sufficient space for two dental implants and an optimum prosthodontic rehabilitation. (Eur J Dent 2010;4:192-196)

scholarly journals Surgical excision of a residual cyst in a patient with previous history of jaw osteonecrosis associated with oral bisphosphonate: A case report

2015 ◽  
Vol 21 (3) ◽  
pp. 191
Author(s):  
Ana Carolina Uchoa Vasconcelos ◽  
Wâneza Dias Borges ◽  
Cláiton Heitz ◽  
Fernanda Gonçalves Salum ◽  
Maria Antonio Zancanaro de Figueiredo ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Previous History ◽  
Surgical Excision ◽  
Osteonecrosis Of The Jaws ◽  
Oral Bisphosphonate ◽  
Prevention And Treatment ◽  
History Of ◽  
Preoperative Procedures ◽  
Jaw Osteonecrosis

Residual cyst is an inflammatory odontogenic cyst resultant from pulp necrosis, where the tooth has already been removed. Bisphosphonates are drugs used in the prevention and treatment of bone metabolism diseases with intense resorption activity, and they have been associated with osteonecrosis of the jaws, an important side effect. The aim of this study was to report a successful surgical treatment of a residual cyst in a patient who had previously developed jaw osteonecrosis associated with sodium alendronate use. We emphasize here the importance of safe preoperative procedures when approaching these patients. 

Nystagmus following Acupuncture – a Case Report

2006 ◽  
Vol 24 (1) ◽  
pp. 33-34 ◽  
Author(s):  
Angela Bradbury ◽  
Jose Botancor ◽  
Adrian White
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Shoulder Pain ◽  
Health Professionals ◽  
Previous History ◽  
Idiosyncratic Reaction ◽  
History Of ◽  
Neurological Response

A 50 year old woman experienced an episode of vertigo and nystagmus about 10 minutes after receiving her first treatment with acupuncture for shoulder pain. The nystagmus was confirmed by several health professionals. She had no previous history of nystagmus, and the symptom was not associated with feelings of faintness. Her blood pressure was 90/50 at the onset of symptoms but returned to normal while the symptoms continued. She recovered spontaneously after about five hours. Nystagmus after acupuncture has not been unequivocally reported before, though dizziness associated with hypotension is common. In this case the association may be coincidental, or a focal neurological response to needling; if the latter, then it should be regarded as an unavoidable idiosyncratic reaction.

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