Cell & Tissue Engineering

1995 ◽  
Vol 18 (8) ◽  
pp. 476-478
Keyword(s):  
Tissue Engineering ◽  
Cell Tissue

Spatially Controllable Deposition of Electrospray Microparticles

2011 ◽  
Author(s):  
Xu Zhang ◽  
Yi Zhao
Keyword(s):  
Tissue Engineering ◽  
Contrast Enhancement ◽  
Electrode Arrays ◽  
Electrical Field ◽  
Nanoscale Particles ◽  
Size Dependent ◽  
Planar Surfaces ◽  
Cell Tissue ◽  
Potential Applications

Electrospray has been widely used in micro/nanotechnology which deposit micro/nanoscale particles on planar surfaces. However, in conventional electrospray approach the distribution of these particles patterned on the collecting surface is poorly controlled. This work introduces a programmable patterning method of electrospray, which microparticles are sprayed on micropatterned collecting chips. By manipulating the local electrical field using a combination of activated and floating electrodes, a good spatial contrast of microparticle patterning is obtained. In addition, the size-dependent contrast enhancement is demonstrated using a series of electrode arrays with different electrode patterns. Combined with encapsulation technique, this unique electrospray method promises potential applications in the field of functional cell/tissue engineering.

scholarly journals Magnetic Bioreactor for Magneto-, Mechano- and Electroactive Tissue Engineering Strategies

Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3340
Author(s):  
Nelson Castro ◽  
Margarida M. Fernandes ◽  
Clarisse Ribeiro ◽  
Vítor Correia ◽  
Rikardo Minguez ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Cells ◽  
Control Design ◽  
Tissue Microenvironment ◽  
Cell Tissue ◽  
Native Cell ◽  
Biomimetic Approach ◽  
Static Conditions ◽  
Electrical Stimuli ◽  
Effective Growth

Biomimetic bioreactor systems are increasingly being developed for tissue engineering applications, due to their ability to recreate the native cell/tissue microenvironment. Regarding bone-related diseases and considering the piezoelectric nature of bone, piezoelectric scaffolds electromechanically stimulated by a bioreactor, providing the stimuli to the cells, allows a biomimetic approach and thus, mimicking the required microenvironment for effective growth and differentiation of bone cells. In this work, a bioreactor has been designed and built allowing to magnetically stimulate magnetoelectric scaffolds and therefore provide mechanical and electrical stimuli to the cells through magnetomechanical or magnetoelectrical effects, depending on the piezoelectric nature of the scaffold. While mechanical bioreactors need direct application of the stimuli on the scaffolds, the herein proposed magnetic bioreactors allow for a remote stimulation without direct contact with the material. Thus, the stimuli application (23 mT at a frequency of 0.3 Hz) to cells seeded on the magnetoelectric, leads to an increase in cell viability of almost 30% with respect to cell culture under static conditions. This could be valuable to mimic what occurs in the human body and for application in immobilized patients. Thus, special emphasis has been placed on the control, design and modeling parameters governing the bioreactor as well as its functional mechanism.

scholarly journals Design of bioreactors for mesenchymal stem cell tissue engineering

2008 ◽  
Vol 83 (4) ◽  
pp. 408-420 ◽  
Author(s):  
Pankaj Godara ◽  
Clive D McFarland ◽  
Robert E Nordon
Keyword(s):  
Tissue Engineering ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Tissue

Spatiotemporal Intracellular Deformation of Cells During Freezing-Induced Cell-Fluid-Matrix Interactions

2013 ◽  
Author(s):  
Soham Ghosh ◽  
J. Craig Dutton ◽  
Bumsoo Han
Keyword(s):  
Tissue Engineering ◽  
Cell Viability ◽  
Three Dimensional ◽  
Tissue Type ◽  
Major Constituent ◽  
Tissue Banks ◽  
Chemical Additives ◽  
Cryoprotective Agents ◽  
Cell Tissue ◽  
The Status

Freezing of biomaterials is emerging as one of the key biotechnologies in cell/tissue engineering, medicine and biology. Its applications include — 1) preservation of cell/tissue engineering products, 2) quality control of biospecimens cryopreserved in tissue banks and repositories, and 3) synthesis procedures of biomaterials such as decellularization of native tissues to create acellular (i.e., cell-free) complex three-dimensional extracellular matrices (ECMs). Traditionally, research efforts have focused on determining optimal freeze/thaw (F/T) protocols with chemical additives, so called cryoprotective agents, for a given cell/tissue-type by comparing the outcomes of F/T protocols, which are mainly gauged by cell viability. Although cell viability is the major constituent, it has recently been recognized that other features beyond viability are also critical to the functionality of biomaterials, including the microstructure of the ECM, the status of cell-matrix adhesion, and the cytoskeletal structure and organization [1, 2, 3].

scholarly journals Commercially available materials as scaffold candidates for adipose-derived stromal/progenitor cell tissue engineering

2014 ◽  
Vol 47 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Yen-Ting Sheen ◽  
Tsai-Ming Lin ◽  
Kao-Ping Chang ◽  
Chung-Sheng Lai ◽  
Sin-Daw Lin ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Progenitor Cell ◽  
Cell Tissue
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