Collision kidney tumor with clear cell renal cell carcinoma and papillary type 1 renal cell carcinoma. A case report and review of the literature

2021 ◽  
pp. 039156032110016
Author(s):  
Stavros Lamprou ◽  
Ioannis Glykas ◽  
Charalampos Fragkoulis ◽  
Georgia Theodoropoulou ◽  
Georgios Koutsonikas ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Simultaneous Occurrence ◽  
Kidney Tumor ◽  
Cell Renal Cell Carcinoma ◽  
Papillary Type

Introduction: The most common renal neoplasms include clear cell, papillary, and chromophobe renal cell carcinomas. The simultaneous occurrence of different histological types of adjacent neoplasms in the same organ is known as a collision tumor. Collision kidney tumors have already been described but only in rare cases. Case description: In this case report we present a 68-year-old man with chronic kidney insufficiency under dialysis who underwent an open right nephrectomy in our department with the histological diagnosis of a collision kidney tumor consisting of clear cell and papillary type 1 renal cell carcinoma. Conclusion: To the best of our knowledge, our case of a collision kidney tumor consisting of clear cell RCC and papillary type 1 RCC, is unique in literature.

scholarly journals MP28-02 COMPARATIVE ANALYSIS OF OUTCOMES OF PAPILLARY TYPE 1 AND TYPE 2 AND CLEAR CELL RENAL CELL CARCINOMA: A MULTI-INSTITUTIONAL STUDY

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Ahmet Bindayi ◽  
Shreyas Joshi ◽  
Alessandro Larcher ◽  
Madhumitha Reddy ◽  
Stephen Ryan ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Comparative Analysis ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Cell Renal Cell Carcinoma ◽  
Papillary Type

scholarly journals Clear cell renal cell carcinoma with vaginal and brain metastases: a case report and literature review

2009 ◽  
Vol 1 (2) ◽  
pp. 16
Author(s):  
Tobe Samuel Momah ◽  
Dhanan Etwaru ◽  
Phillip Xiao ◽  
Vasantha Kondamudi
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Cell Renal Cell Carcinoma

scholarly journals Implications of Programmed Death Ligand-1 Positivity in Non-Clear Cell Renal Cell Carcinoma

2018 ◽  
Vol 5 (4) ◽  
pp. 6-13 ◽  
Author(s):  
Juan Chipollini ◽  
Mounsif Azizi ◽  
Charles C Peyton ◽  
Dominic H Tang ◽  
Jasreman Dhillon ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Type I ◽  
Cell Renal Cell Carcinoma ◽  
Programmed Death Ligand 1 ◽  
Programmed Death ◽  
Papillary Type

The purpose of this study was to assess the prognostic value of programmed death ligand-1 (PD-L1) positivity in a non-clear cell renal cell carcinoma (non-ccRCC) cohort. PD-L1 expression was evaluated by immunohistochemistry (IHC) using formalin-fixed paraffin-embedded (FFPE) specimens from 45 non-ccRCC patients with available tissue. PD-L1 positivity was defined as ?1% of staining. Histopathological characteristics and oncological outcomes were correlated to PD-L1 expression. Cancer-specific survival (CSS) and recurrence-free survival (RFS) stratified by PD-L1 status were estimated using the Kaplan–Meier method. Median age was 58 years and median follow-up was 40 months. Non-ccRCC subtypes included sarcomatoid (n = 9), rhabdoid (n = 6), medullary (n = 2), Xp11.2 translocation (n = 2), collecting duct (n = 1), papillary type I (n = 11), and papillary type II (n = 14). PD-L1 positivity was noted in nine (20%) patients. PD-L1 positivity was significantly associated with higher Fuhrman nuclear grade (P = 0.048) and perineural invasion (P = 0.043). Five-year CSS was 73.2 and 83% for PD-L1 positive and negative tumors, respectively (P = 0.47). Five-year RFS was 55.6 and 61.5% for PD-L1 positive and negative tumors, respectively (P = 0.58). PD-L1 was expressed in a fifth of non-ccRCC cases and was associated with adverse histopathologic features. Expression of biomarkers such PD-L1 may help better risk-stratify non-ccRCC patients to guide treatment decisions and follow-up strategies.

scholarly journals Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 607 ◽  
Author(s):  
José I. López
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Papillary Renal Cell Carcinoma ◽  
Rare Tumor ◽  
Tumor Subtype ◽  
Cell Renal Cell Carcinoma ◽  
Gross Examination

A multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination. A fifth central tumor corresponded to a conventional clear cell renal cell carcinoma. Biphasic squamoid alveolar renal cell carcinoma is a rare tumor that has been very recently characterized as a distinct histotype within the spectrum of papillary renal cell carcinoma. Immunostaining with cyclin D1 seems to be specific of this tumor subtype. This is the first reported case with multifocal presentation.

Sign in / Sign up

Export Citation Format

Share Document