Phaeochromocytoma and Myopathy

1992 ◽  
Vol 59 (2) ◽  
pp. 56-58
Author(s):  
A. Furino ◽  
C. Massagli
Keyword(s):  
Differential Diagnosis ◽  
Orthostatic Hypotension ◽  
Antihypertensive Drugs ◽  
Preoperative Period ◽  
Combined Action ◽  
Adrenergic Blocking

The author reports the case of a 67-year old woman with phaeochromocytoma, orthostatic hypotension, muscular exhaustion and weakness. After differential diagnosis with primary myopathy, MEN type IIb and Shy-Drager syndrome, the disease appears to be due to the combined action of the secretion of epinephrine and antihypertensive drugs, accentuated by the administration of alpha-adrenergic blocking drugs in the preoperative period.

Massive Clonidine Ingestion with Hypertension in a 9-Month-Old Infant

PEDIATRICS ◽  
1983 ◽  
Vol 72 (4) ◽  
pp. 500-502
Author(s):  
Pablo Yagupsky ◽  
Rafael Gorodischer
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Drugs ◽  
Complete Recovery ◽  
Blocking Agent ◽  
Assisted Ventilation ◽  
Antagonistic Effect ◽  
Arterial Blood ◽  
Clonidine Poisoning ◽  
Adrenergic Blockers ◽  
Adrenergic Blocking

The antihypertensive drug clonidine has a double and antagonistic effect on arterial blood pressure. As a result of activation of peripheral α-adrenergic receptors, it causes a transient increase in blood pressure; by a central action it decreases sympathetic tone which results in sustained bradycardia and hypotension. Both central and peripheral effects are experimentally blocked by tolazoline, an α-adrenergic blocking agent. The toxic symptoms seen in clonidine poisoning are usually produced by the central effect. A case of severe clonidine poisoning in a 9-month-old infant is reported. The clinical picture included coma, miosis, apneic spells, bradycardia, and hypertension. Rapid and complete recovery was obtained with supportive treatment that included assisted ventilation. No adrenergic blockers or antihypertensive drugs were given. Use of tolazoline in cases of clonidine overdose in children remains controversial. Supportive measures alone may be adequate for even the most severe cases.

scholarly journals Possibilities of multiparametric MRI in the differential diagnosis of histological types of cervical cancer in the preoperative period

2016 ◽  
Vol 12 (2) ◽  
pp. 60-69
Author(s):  
E. V. Tarachkova ◽  
M. A. Shorikov ◽  
V. O. Panov ◽  
V. V. Kuznetsov ◽  
L. Sh. Usmanova ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Differential Diagnosis ◽  
Multiparametric Mri ◽  
Preoperative Period ◽  
Histological Types

Autonomic Disorders

2017 ◽  
Author(s):  
Karl E. Misulis ◽  
E. Lee Murray
Keyword(s):  
Differential Diagnosis ◽  
Orthostatic Hypotension ◽  
Systemic Disease ◽  
Neurologic Manifestations ◽  
Autonomic Disorders ◽  
Autonomic Insufficiency

Autonomic difficulty is usually a component of a systemic disease with other neurologic manifestations. A commonality is orthostatic hypotension for most of these. Once the diagnosis of autonomic insufficiency has been made, the differential diagnosis includes disorders described in this chapter.

scholarly journals Medication and nutritional supplement use before and after bariatric surgery

2016 ◽  
Vol 134 (6) ◽  
pp. 491-500 ◽  
Author(s):  
Charline Fernanda Backes ◽  
Edyane Lopes ◽  
Airton Tetelbom ◽  
Isabela Heineck
Keyword(s):  
Bariatric Surgery ◽  
Drug Use ◽  
Antihypertensive Drugs ◽  
Nutritional Supplement ◽  
Morbidly Obese ◽  
Preoperative Period ◽  
Porto Alegre ◽  
Supplement Use ◽  
Before And After ◽  
The Impact

ABSTRACT CONTEXT AND OBJECTIVE: Bariatric surgery has been an effective alternative treatment for morbid obesity and has resulted in decreased mortality, better control over comorbidities and reduced use of drugs. The objective of this study was to analyze the impact of bariatric surgery on medication drug and nutritional supplement use. DESIGN AND SETTING: Longitudinal study of before-and-after type, on 69 morbidly obese patients in a public hospital in Porto Alegre. METHODS: Through interviews, the presence of comorbidities and use of drugs with and without prescription were evaluated. RESULTS: Among the 69 patients interviewed, 85.5% had comorbidities in the preoperative period, with an average of 2.3 (± 1.5) per patient. The main comorbidities reported were hypertension, diabetes and dyslipidemia. 84.1% of the patients were using prescribed drugs in the preoperative period. The mean drug use per patient was 4.8, which decreased to 4.4 after the procedure. The surgery enabled significant reduction in use of most antidiabetic (84%), antilipemic (77%) and antihypertensive drugs (49.5%). On the other hand, there was a significant increase in use of multivitamins and drugs for disorders of the gastrointestinal tract. The dosages of most of the drugs that continued to be prescribed after surgery were decreased, but not significantly. CONCLUSION: After bariatric surgery, there were increases in the use of vitamins, gastric antisecretory drugs and antianemic drugs. Nevertheless, there was an overall reduction in drug use during this period, caused by suspension of drugs or dose reduction.

scholarly journals Nebivolol - A Review

1970 ◽  
Vol 6 (2) ◽  
pp. 93-96
Author(s):  
Uzzal Kanti Das ◽  
Syed Ali Ahsan ◽  
Mohammad Salman ◽  
Mohammad Ferdous Ur Rahaman ◽  
Md Mizanur Rahman Khan ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Pressure ◽  
Arterial Stiffness ◽  
Antihypertensive Drugs ◽  
Peripheral Resistance ◽  
Blood Pressure Lowering Effect ◽  
Pressure Lowering ◽  
Β Blocker ◽  
General Response ◽  
Adrenergic Blocking

Nebivolol is a vasodilating β-blocker, which can be distinguished from other β-blockers by its haemodynamic profile. It combines β-adrenergic blocking activity with a vasodilating effect mediated by the endothelial Larginine nitric oxide (NO) pathway. The blood pressure lowering effect of nebivolol is linked to a reduction in peripheral resistance and an increase in stroke volume and preservation of cardiac output. Clinical trials have demonstrated that nebivolol reduces blood pressure similarly to atenolol, bisoprolol, amlodipine, nifedipine, lisinopril, and hydrochlorothiazide. The tolerability of nebivolol is similar to or better than that of these agents. In general, response rates to treatment are higher and the frequency and severity of adverse events are either comparable or lower with nebivolol. Endothelium-derived NO is important in the regulation of large arterial stiffness, which in turn is a major risk factor for cardiovascular disease. Therefore, antihypertensive drugs, such as nebivolol, that also improve endothelial function and decrease arterial stiffness, may contribute to a reduction in cardiovascular risk.Key words: Vasodilating β-blocker; nitric oxide (NO); peripheral resistance; arterial stiffness DOI: 10.3329/uhj.v6i2.7254University Heart Journal Vol. 6, No. 2, July 2010 pp.93-96

scholarly journals Acute Secondary Adrenal Insufficiency Misdiagnosed as Acute Cholecystitis

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Moslem Sedaghattalab ◽  
Amir Hossein Doustimotlagh
Keyword(s):  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Orthostatic Hypotension ◽  
Acute Cholecystitis ◽  
Adrenal Insufficiency ◽  
Adrenocorticotropic Hormone ◽  
Unusual Case ◽  
Pituitary Hormones ◽  
Secondary Adrenal Insufficiency ◽  
Abdominal Tenderness

Hypopituitarism refers to insufficient secretion of the pituitary hormones. Patients with acute adrenocorticotropic hormone (ACTH) deficiency may be presented with fatigue, dizziness, orthostatic hypotension, hypoglycemia, nausea, vomiting, or nonspecific abdominal pain. This study described an unusual case of hypopituitarism in a patient who presented with general abdominal pain, abdominal tenderness, nausea, vomiting, hypotension, and hypoglycemia. At first, the patient was admitted with the diagnosis of acute cholecystitis, but after treatment of hypopituitarism and adrenal insufficiency, his symptoms resolved completely, without the need for surgery. Hypopituitarism and secondary adrenal insufficiency should be considered in the differential diagnosis of the patients who present with acute abdomen, hypotension, or hypoglycemia.

scholarly journals Prevalence and coincidence of hypertension and orthostatic hypotension in pre- and centenarians and their effect on mortality: preliminary results of Moscow centenarian study

2020 ◽  
Vol 26 (1) ◽  
pp. 37-42
Author(s):  
K. A. Eruslanova ◽  
L. V. Matchekhina ◽  
Y. V. Kotovskaya ◽  
N. K. Runikhina ◽  
O. N. Tkacheva
Keyword(s):  
Blood Pressure ◽  
Orthostatic Hypotension ◽  
Antihypertensive Drugs ◽  
Factors Affecting ◽  
Wide Range ◽  
Moscow City ◽  
Minimum Age ◽  
History Of ◽  
Study Participants ◽  
Design And Methods

Objective. To estimate the prevalence and impact on mortality of arterial hypertension (HTN) and orthostatic hypotension (OH) in centenarians (95 years and older) in Moscow.Design and methods. The study participants were 82 super-long-livers of Moscow city aged 95 years and older (minimum age of 95 years, maximum 105 years), who underwent a comprehensive geriatric assessment at home by a multidisciplinary team (geriatrician, nurse and social worker). The following prospective observation lasted for three years (36 months).Results. Past medical history of HTN was noted in 78 %. The mean systolic blood pressure (SBP) in the supine position was 151 ± 27,9 mm Hg (100–216 mm Hg), and the diastolic blood pressure (DBP) 74 ± 12,8 mm Hg (44–197 mm Hg). OH was detected in 31 % of 61 long-livers who was able to perform an orthostatic test. The presence of OH was not associated with the higher intake of antihypertensive drugs. Within three years, 44 study participants died. The level of blood pressure (BP), history of HTN, and the presence of OH did not affect mortality (p > 0,05).Conclusions. Centenarians have a wide range of SBP and DBP, high prevalence of HTN and OH. BP level, presence of HTN and OH did not affect mortality over 3 year period. Further investigation is needed to understand better the health status of long-livers and factors affecting the prognosis.

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