scholarly journals Knowledge About Alzheimer’s Disease and Awareness of Alzheimer’s Disease–Related Services in Older Korean Americans: The Role of Social Capital

2020 ◽  
pp. 073346482091153 ◽  
Author(s):  
Nan Sook Park ◽  
Yuri Jang ◽  
Min-Kyoung Rhee ◽  
Hyunwoo Yoon ◽  
David A. Chiriboga
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Social Capital ◽  
Social Network ◽  
Korean Americans ◽  
Prior Exposure ◽  
Network Activity ◽  
Activity Participation ◽  
Older Korean Americans

The purpose of the study was to investigate factors associated with Alzheimer’s Disease (AD)-related knowledge and service awareness in older Korean Americans. Considering the importance of social resources in the lives of older immigrants, the focus was on exploring the role of social capital–related factors (e.g., prior exposure to AD, social network, activity participation, and community social cohesion) on AD knowledge and service awareness. Data were drawn from the Study of Older Korean Americans (SOKA; N = 2,150; Mage = 73.41, SD = 7.97). Findings highlight the critical roles of prior exposure to AD and social network influencing both AD knowledge and service awareness, with activity participation also being associated with the latter. Results suggest that particular attention should be paid to individuals who are culturally and socially isolated when considering interventions.

The Relations of Social Network Types With Mental Distress Among Older Korean Americans: The Interactive Role of Living Arrangement

2021 ◽  
pp. 016402752199978
Author(s):  
Nan Sook Park ◽  
Yuri Jang ◽  
David A. Chiriboga ◽  
Soondool Chung
Keyword(s):  
Social Network ◽  
Mental Distress ◽  
Living Arrangement ◽  
Korean Americans ◽  
Latent Profile Analyses ◽  
Restricted Group ◽  
Criterion Variables ◽  
Best Fit ◽  
Older Korean Americans

The purpose of this study is to identify social network types in older Korean Americans and to examine their direct associations, as well as interactions with living arrangement, on mental distress. Drawn from the Study of Older Korean Americans (SOKA), participants were aged 60 or over and lived in five states. Analyses included 2,140 cases surveyed during 2017−2018. To identify social network types, latent profile analyses were conducted using 10 network-related criterion variables. A model with five social network types was identified as best fit. The groups were labeled as diverse, moderately diverse, family deficit, friend deficit, and restricted. As hypothesized, greater mental distress was associated with belonging to more deprived networks such as family deficit and restricted groups. Interaction effects also suggest that members of the restricted group were more distressed when they lived alone than when they lived with others. Implications based on the results are discussed.

scholarly journals COGNITION, SELF-RATED COGNITIVE HEALTH, AND CONCERNS ABOUT ALZHEIMER’S DISEASE IN OLDER KOREAN AMERICANS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S265-S266
Author(s):  
Yuri Jang ◽  
Nan Sook Park ◽  
David Chiriboga ◽  
Hyunwoo Yoon ◽  
Min-Kyoung Rhee
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Performance ◽  
Indirect Effect ◽  
Poor Performance ◽  
Korean Americans ◽  
Cognitive Status ◽  
Cognitive Health ◽  
Mediation Analyses ◽  
Older Korean Americans

Abstract Responding to the dearth of research on cognitive health in older ethnic minorities, the present study explored the associations among cognitive performance, self-rated cognitive health, and concerns about Alzheimer’s Disease (AD) in older Korean Americans. We hypothesized that (1) cognitive performance and self-rated cognitive health would be moderately associated; (2) both cognitive performance and self-rated cognitive health would be associated with concerns about AD; and (3) the effect of cognitive performance on concerns about AD would be mediated by self-rated cognitive health. Analyses of the survey data of 2,150 older Korean Americans (mean age = 73.2) residing in five states provided support for the hypotheses. Cognitive performance, measured with a Korean version of the Mini-Mental State Exam (MMSE), and a single item asking respondents to rate their overall cognitive status on a 5-point scale (excellent/very good/good/fair/poor) were moderately associated. Both poor performance in the MMSE and negative ratings of cognitive health status were associated with increased concerns about AD. Mediation analyses using the macro PROCESS showed that the indirect effect of cognitive performance on the concerns about AD through self-rated cognitive health (−.01 [.002]) was significant (bias corrected 95% confidence interval for the indirect effect = −.02, −.01). That is, the effect of cognitive performance on the concerns about AD was mediated by individuals’ subjective evaluations of their cognitive health. Findings not only help better understand the psychological mechanisms that underlie cognitive health and AD concerns but also suggest avenues for interventions.

Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease

2011 ◽  
Vol 44 (06) ◽  
Author(s):  
K Lerche ◽  
M Willem ◽  
K Kleinknecht ◽  
C Romberg ◽  
U Konietzko ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Role of melatonin in regulating neurogenesis: Implications for the neurodegenerative pathology and analogous therapeutics for Alzheimer’s disease

2020 ◽  
Vol 3 (2) ◽  
pp. 216-242 ◽  
Author(s):  
Mayuri Shukla ◽  
Areechun Sotthibundhu ◽  
Piyarat Govitrapong
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Adult Neurogenesis ◽  
Adult Brain ◽  
Therapeutic Approaches ◽  
Therapeutic Implications ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Progenitor Cell Proliferation

The revelation of adult brain exhibiting neurogenesis has established that the brain possesses great plasticity and that neurons could be spawned in the neurogenic zones where hippocampal adult neurogenesis attributes to learning and memory processes. With strong implications in brain functional homeostasis, aging and cognition, various aspects of adult neurogenesis reveal exuberant mechanistic associations thereby further aiding in facilitating the therapeutic approaches regarding the development of neurodegenerative processes in Alzheimer’s Disease (AD). Impaired neurogenesis has been significantly evident in AD with compromised hippocampal function and cognitive deficits. Melatonin the pineal indolamine augments neurogenesis and has been linked to AD development as its levels are compromised with disease progression. Here, in this review, we discuss and appraise the mechanisms via which melatonin regulates neurogenesis in pathophysiological conditions which would unravel the molecular basis in such conditions and its role in endogenous brain repair. Also, its components as key regulators of neural stem and progenitor cell proliferation and differentiation in the embryonic and adult brain would aid in accentuating the therapeutic implications of this indoleamine in line of prevention and treatment of AD.   

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