The Great Lakes: a Historical Overview

1996 ◽  
Vol 12 (3-4) ◽  
pp. 303-313 ◽  
Author(s):  
Heraline E. Hicks

The Great Lakes are collectively the largest inland body of freshwater on this planet. For more than two hundred years, the Great Lakes basin has been used as a resource for industry, agriculture, shipping, and recreation. The physical characteristics of the basin and the long retention time of chemicals in the lakes combine to make this huge freshwater resource a repository for chemical by-products of these activities. Many of the more than one thousand chemicals detected in the waters, sediment, or biota of the Great Lakes have known toxic effects. This overview will identify the 11 most persistent toxic chemicals known as "critical" Great Lakes pollutants. It also will describe some of the adverse health effects that have been observed in fish and other wildlife because of exposure to these pollutants. Finally. it will discuss some of the early human health studies that 1) have demonstrated a correlation between increased body burdens and fish consumption, and 2) suggest an association between consumption of contaminated Great Lakes fish and adverse human health effects.

1996 ◽  
Vol 12 (3-4) ◽  
pp. 467-476 ◽  
Author(s):  
Heraline E. Hicks ◽  
Robert F. Spengler

Epidemiological studies of exposed human populations can provide valuable evidence of human health effects. Information has been sparse on human health effects associated with consumption of contaminated Great Lakes fish. As part of its Great Lakes Human Health Effects Research Program, the Agency for Toxic Substances and Disease Registry (ATSDR) has funded ten projects. Of these studies, eight are epidemiologic investigations of human exposure and potential health effects from consumption of contaminated fish. To strengthen and to enhance the findings and comparability across the health studies, ATSDR has initiated several activities. These activities include harmonizing questionnaires, analytical protocols, human health end points, and contaminants tested. Also included is the establishment of a quality assurance and quality control (QA/QC) program and tissue bank. These activities will allow ATSDR to enhance exposure assessment in the Great Lakes basin. In addition, these research activities allow ATSDR to evaluate and to interpret data across all the projects, including a basin-wide health risk analysis on exposure, levels of contaminants or body burden, and the potential for human health effects from exposure to Great Lakes contaminants.


1996 ◽  
Vol 12 (3-4) ◽  
pp. 315-325 ◽  
Author(s):  
Christopher T. Derosa ◽  
Barry L. Johnson

The goal of the Agency for Toxic Substances and Disease Registry's (ATSDR) Great Lakes Human Health Effects Research Program is to identify at-risk populations and to prevent potential human health effects associated with exposure to chemical contaminants in the Great Lakes basin. While this research effort is mandated by the Great Lakes Critical Programs Act of 1990, it also represents a significant opportunity to define a broader model or strategy for other regional or systems-level studies of potential health effects in at-risk populations. This article describes the strategy developed by ATSDR for this purpose in the Great Lakes Basin, as well as the program's specific research objectives and current status. It also outlines the projected implications of this research effort for greater comprehension of the potential health effects of exposure to contaminants in the Great Lakes Basin.


Epidemiology ◽  
1996 ◽  
Vol 7 (Supplement) ◽  
pp. S39
Author(s):  
H E HIÇKS ◽  
W CIBULAS ◽  
Z ROSEMOND ◽  
C DeROSA

Author(s):  
PA Ganichev

Introduction: Polymer products have become inexpensive, convenient and widely used in all spheres of everyday life recently. Microplastics are found in seawater, wastewater, fresh water, foodstuffs, and air. Over the past few years, the presence of microplastics in treated tap and bottled water has been reported, raising questions and concerns about their potential human health effects. Objective: To summarize and systematize the results of studying health effects of exposure to microplastics in potable water. Materials and methods: A literature review was done based on ten topical articles and reviews published in 2014–2021 out of 64 sources found in the PubMed and Scopus international databases and the Russian Science Citation Index (RSCI). Results and conclusions: Generalization and systematization of the published research data demonstrated the lack of strong evidence to draw conclusions about human health effects of microplastics. Information on toxicokinetics and toxicodynamics of ingested microplastic particles is absent just like the studies of the most common shapes and sizes of plastic particles and health risks from exposure to such particles in drinking water.


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