Methyl-CpG-binding Protein 2 (MECP2) Gene Mutations in an Italian Sample of Patients with Pervasive Developmental Disorder and Mental Retardation

2009 ◽  
Vol 24 (6) ◽  
pp. 772-774 ◽  
Author(s):  
Antonia Parmeggiani ◽  
Maria Rita Tedde ◽  
Annalisa Arbizzani ◽  
Annio Posar ◽  
Maria Cristina Scaduto ◽  
...  
Keyword(s):  
Mental Retardation ◽  
Pervasive Developmental Disorder ◽  
Developmental Disorder ◽  
Binding Protein ◽  
Gene Mutations ◽  
Mecp2 Gene ◽  
Italian Sample

Behaviour Problems of the Mentally Retarded

1991 ◽  
Vol 36 (10) ◽  
pp. 712-717 ◽  
Author(s):  
Natalie Grizenko ◽  
Helen Cvejic ◽  
Stephen Vida ◽  
Liliane Sayegh
Keyword(s):  
Public Policy ◽  
Mental Retardation ◽  
Psychiatric Disorder ◽  
Pervasive Developmental Disorder ◽  
Medical Diagnosis ◽  
Developmental Disorder ◽  
Mentally Retarded ◽  
Group Homes ◽  
Child Behaviour ◽  
Behaviour Problems

The behaviour profiles of 176 mentally retarded individuals from two reception centres and nine group homes were assessed. The correlations between behaviour and age, sex, degree of mental retardation, etiology of mental retardation and medical diagnosis were assessed using the Revised Child Behaviour Profile. The severity of behaviour disturbance did not vary with age or medical diagnosis. The moderately retarded subjects presented with more severe behaviour problems, such as aggression, than the severely mentally retarded subjects. The variable most predictive of behavioural problems was etiology of the disorder. Individuals with Down's syndrome had significantly fewer behaviour disturbances and those with autism and pervasive developmental disorder had significantly more behaviour disturbances than other subjects. A psychiatric disorder was found in 10.2% of the sample. The implications of these findings are discussed with respect to public policy.

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