scholarly journals Young’s modulus repeatability assessment using cycling compression loading on cancellous bone

Author(s):  
S Guérard ◽  
Y Chevalier ◽  
H Moreschi ◽  
M Defontaine ◽  
S Callé ◽  
...  

For various applications, precision of the Young’s modulus of cancellous bone specimens is needed. However, measurement variability is rarely given. The aim of this study was to assess the Young’s modulus repeatability using a uniaxial cyclic compression protocol on embedded specimens of human cancellous bone. Twelve specimens from 12 human calcanei were considered. The specimens were first defatted and then 1 or 2 mm at the ends were embedded in an epoxy resin. The compression experiment consists in applying 20 compressive cycles between 0.2 per cent and 0.6 per cent strain with a 2 Hz loading frequency. The coefficient of variation of the current protocol was found to be 1.2 per cent. This protocol showed variability similar to the end-cap technique (considered as a reference). It can be applied on porous specimen (especially human bone) and requires minimal bone length to limit end-artifact variability. The current method could be applied in association with noninvasive measurements (such as ultrasound) with full compatibility. This possibility opens the way for bone damage follow-up based on Young’s modulus monitoring.

Author(s):  
F. El Masri ◽  
E. Sapin de Brosses ◽  
K. Rhissassi ◽  
W. Skalli ◽  
D. Mitton

2018 ◽  
Vol 933 ◽  
pp. 309-313
Author(s):  
Yi Hao Du ◽  
Si Yuan He ◽  
Meng Ke Huo ◽  
Ping Zhou ◽  
Qiang Chen ◽  
...  

Trabecular bone, widely presented in the ends of long bones and chine, is a typically porous structure which provides a multifunction such as light weight, undertaking load, impact energy buffer and hosting marrow cells. The structure of trabecular is a dominant factor for the strength of cancellous bone. The prediction of the trabecular bone’s mechanical properties depending on the trabecular structure is very useful for the diagnosis and treatment of osteoporosis. The object of this study is to establish a relationship between the mechanical properties and topological, morphological parameters of trabecular bone. The 50 3-D data of cancellous bone are selected from the CT images of three caput femurs and disposed in BoneJ, through which the BV/TV, SMI and genus parameters of each samples are obtained. The deformation behaviors of trabecular bone are simulated in ABAQUS through uniaxial compression on the 3-D model derived from stack images. Then linear-regression analyses are conducted on the BV/TV, genus, SMI and apparent Young’s modulus, resulting a high correlation (R^2=0.84) between the Young’s modulus and the hybrid parameter derived from SMI and normalized genus, corresponding to morphological and topological parameter of the samples respectively. The result indicates that it’s promising to establish the relationship between mechanical properties of trabecular bone and their topological and morphological parameters.


2003 ◽  
Vol 17 (08n09) ◽  
pp. 1381-1387 ◽  
Author(s):  
Fumio Nogata ◽  
Akira Shimamoto ◽  
Toshihiko Habu

A new method for estimating in vivo bone strength using ultrasound inspection is described, which can allow diagnose of osteoporosis from the viewpoint of mechanical integrity. The method was based on the two-dimensional area fraction of bone calculated from the difference in the speed of ultrasound propagation through cancellous bone. Then bulk Young's modulus was calculated for various architectures of the cancellous bone with the bone area fraction (S) using finite element method. Since there was a good relationship between the BMD (bone mineral density) by DXA (dual energy x-ray absorptiometry) method and the bone area fraction by ultrasound inspection, the technique also allows the estimation of in vivo BMD of the spine, which has been traditionally used at medical area to diagnose osteoporosis. Note that the periodic estimation of the bulk Young's modulus and strength applying the technique is effective to predict the fracture risk for in vivo bone.


1994 ◽  
Vol 27 (8) ◽  
pp. 1095-1099 ◽  
Author(s):  
D.R. Sumner ◽  
T.L. Willke ◽  
A. Berzins ◽  
T.M. Turner

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