Economic Evaluation of the National Immunization Program of Rotavirus Vaccination for Children in Korea

2012 ◽  
Vol 25 (2) ◽  
pp. 145-158 ◽  
Author(s):  
Hye-Young Kang ◽  
Ki Hwan Kim ◽  
Ji Hong Kim ◽  
Hwang Min Kim ◽  
Jinkyung Kim ◽  
...  
Keyword(s):  
Reduction Rate ◽  
Cost Effective ◽  
National Immunization Program ◽  
Immunization Program ◽  
Specific Data ◽  
Rotavirus Vaccination ◽  
National Immunization ◽  
Rotavirus Diarrhea ◽  
The Cost ◽  
Epidemiological Characteristics

The authors assessed the cost-effectiveness of rotavirus vaccination to develop an evidence-based national immunization program in Korea. A Markov model was constructed to compare the costs and clinical outcomes of vaccination versus no vaccination. The birth cohort of 493189 infants in 2007 was followed until the age of 5 years. Korea-specific data for epidemiological characteristics and economic burden of rotavirus diarrhea were used for the modeled estimation. Efficacy of RotaTeq® was based on a recent clinical trial. Rotavirus vaccination would prevent 181238 symptomatic cases (reduction rate = 63.2%) over 5 years after birth. From the societal perspective, at a vaccination cost of 100000 Korean won (KW; 1 US$ ≈ 1200 KW) per dose, universal vaccination would cost 375 620 KW per case averted. The breakeven price of vaccine was 56061 KW. Rotavirus vaccination would reduce the burden of the disease substantially and be a cost-effective strategy to prevent rotavirus diarrhea in Korea.

Is it cost-effective to introduce rotavirus vaccination in the Dutch national immunization program?

Vaccine ◽  
2010 ◽  
Vol 28 (14) ◽  
pp. 2624-2635 ◽  
Author(s):  
Marie-Josee J. Mangen ◽  
Yvonne T.H.P. van Duynhoven ◽  
Harry Vennema ◽  
Wilfrid van Pelt ◽  
Arie H. Havelaar ◽  
...  
Keyword(s):  
Cost Effective ◽  
National Immunization Program ◽  
Immunization Program ◽  
Rotavirus Vaccination ◽  
National Immunization

scholarly journals Estimating the cost-effectiveness of an infant 13-valent pneumococcal conjugate vaccine national immunization program in China

PLoS ONE ◽  
2018 ◽  
Vol 13 (7) ◽  
pp. e0201245 ◽  
Author(s):  
Kunling Shen ◽  
Matthew Wasserman ◽  
Dongdong Liu ◽  
Yong-Hong Yang ◽  
Junfeng Yang ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Conjugate Vaccine ◽  
Pneumococcal Conjugate Vaccine ◽  
National Immunization Program ◽  
Immunization Program ◽  
National Immunization ◽  
The Cost

National Childhood Vaccine Injury Compensation Act

PEDIATRICS ◽  
1988 ◽  
Vol 82 (2) ◽  
pp. 264-269
Author(s):  
MARTIN H. SMITH
Keyword(s):  
American Academy ◽  
Pivotal Role ◽  
National Immunization Program ◽  
Immunization Program ◽  
The Past ◽  
American Academy Of Pediatrics ◽  
National Immunization ◽  
Equal Importance ◽  
Childhood Vaccine ◽  
The Cost

The past four decades have been years of phenomenal progress in all of medicine, yet in terms of numbers of lives saved or in years of productive lives spared, nothing has equaled the record of preventative pediatrics, specifically, our national immunization program. In the past several years, however, this immunization program has almost fallen into shambles. The sources of this reversal would have been from vaccine liability leading to exorbitant costs or loss of supply of vaccines. In the 1970s and 1980s, a series of crises that were only narrowly averted threatened interruption of the national immunization program. It is now worthwhile to trace the events of the past several years so that we can review the continuity of the course of events through those years to understand the necessity for the specific resolution of these problems in the form of the National Childhood Vaccine Injury Compensation Act. The American Academy of Pediatrics played a leading and pivotal role in the long struggle to enact this legislation. It is expected that the act should be the means of avoiding any future threats to our national immunization program through loss of supply. Furthermore, and of equal importance, after time for stabilization and experience with its administration, the act should reduce the cost of vaccines. The courts have dealt with the matter of vaccine injury in an irregular and sometimes unpredictable manner. This legislation should provide a more predictable and just outcome for those few who suffer vaccine injuries. Because this is the first major legislation the Academy has undertaken, the membership should be informed of the time involved in promoting passage of this legislation: the costs in hours by the members, officers, and staff, as well as the monetary costs to the Academy.

scholarly journals Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Babatunde Olanrewaju Motayo ◽  
Adedayo Omotayo Faneye ◽  
Johnson Adekunle Adeniji
Keyword(s):  
Molecular Epidemiology ◽  
Molecular Data ◽  
National Immunization Program ◽  
Immunization Program ◽  
Molecular Surveillance ◽  
Rotavirus A ◽  
Rotavirus Vaccination ◽  
National Immunization ◽  
New Genotype ◽  
Dominant Genotype

Rotavirus induced acute gastroenteritis AGE has been a major disease burden in Nigeria, since it was first reported in 1985. Prevalence rates have increased with severe public health consequences particularly among children. The vaccine Rotarix® has been introduced and is commercially available in Nigeria. However routine rotavirus vaccination is yet to be introduced into the National Immunization Program. Molecular epidemiology of rotavirus in Nigeria has shown the presence of various genotypes, with genotype G12P[8] being the most recent introduction. There are however gaps in molecular data on rotavirus in Nigeria. We therefore reviewed molecular data on rotavirus isolated in Nigeria and also analyzed VP4 and VP7 genes of Nigerian rotavirus strains in Genbank. We have shown that there is a distinct trend in rotavirus molecular epidemiology in Nigeria, with new genotype introductions occurring after the year 2010. We also observed from our analysis the emergence of genotype G12 Lineage III as a dominant genotype. This information elucidates rotavirus molecular epidemiology in Nigeria and gives insight to the expanding landscape of rotavirus genotypes. We recommend the institution of molecular surveillance country wide, before considering the inclusion of rotavirus vaccination into the National Immunization Program in Nigeria, in other to monitor evolution of divergent or recombinant strains.

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