Complex PTSD and personality disorder in ICD-11: when to assign one or two diagnoses?

2021 ◽  
pp. 103985622110142
Author(s):  
Simon Ungar Felding ◽  
Line Bang Mikkelsen ◽  
Bo Bach

Objective: To outline overlap and boundaries between ICD-11 definitions of complex post-traumatic stress disorder (C-PTSD) and personality disorder (PD) and propose guiding principles that may assist practitioners in assigning one or both of the two diagnoses. Conclusions: The ICD-11 definitions for C-PTSD and PD are substantially comparable in terms of self- and interpersonal problems, and childhood trauma may be at the root of both disorders. The ICD-11 formally recognizes this overlap and allows the assignment of both diagnoses at the same time. The C-PTSD diagnosis essentially differs from a PD diagnosis by requiring a history of trauma and PTSD symptoms. Moreover, C-PTSD typically involves stable and persistent patterns of negative self-perception while emphasizing avoidant interpersonal patterns. In comparison, the PD diagnosis may differ from C-PTSD by allowing an unstable or internally contradictory sense of self, which may involve both overly negative and overly positive self-views. When the diagnostic requirements for both C-PTSD and PD are met, only the C-PTSD diagnosis should be assigned, unless the PD diagnosis may contribute with clinically useful information that is not sufficiently covered by the C-PTSD diagnosis. The outlined similarities and boundaries must be further corroborated by future empirical studies.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fumikazu Hayashi ◽  
◽  
Tetsuya Ohira ◽  
Hironori Nakano ◽  
Masanori Nagao ◽  
...  

Abstract Background It has been reported that psychological stress affects bone metabolism and increases the risk of fracture. However, the relationship between bone fractures and post-traumatic stress disorder (PTSD) is unclear. This study aimed to evaluate the effects of disaster-induced PTSD symptoms on fracture risk in older adults. Methods This study evaluated responses from 17,474 individuals aged ≥ 65 years without a history of fractures during the Great East Japan Earthquake who answered the Mental Health and Lifestyle Survey component of the Fukushima Health Management Survey conducted in 2011. The obtained data could determine the presence or absence of fractures until 2016. Age, sex, physical factors, social factors, psychological factors, and lifestyle factors were subsequently analyzed. Survival analysis was then performed to determine the relationship between the fractures and each factor. Thereafter, univariate and multivariate Cox proportional hazard models were constructed to identify fracture risk factors. Results In total, 2,097 (12.0%) fractures were observed throughout the follow-up period. Accordingly, univariate and multivariate Cox proportional hazard models showed that PTSD symptoms (total PTSD checklists scoring ≥ 44) [hazard ratio (HR): 1.26; 95% confidence interval (CI): 1.10–1.44; P = 0.001], history of cancer (HR: 1.49; 95% CI: 1.24–1.79; P < 0.001), history of stroke (HR: 1.25; 95% CI: 1.03–1.52; P = 0.023), history of heart disease (HR: 1.30; 95% CI: 1.13–1.50; P < 0.001), history of diabetes (HR: 1.23; 95% CI: 1.09–1.39; P < 0.001), current smoking (HR: 1.29; 95% CI: 1.02–1.63; P = 0.036), and high dissatisfaction with sleep or no sleep at all (HR: 1.33; 95% CI: 1.02–1.74; P = 0.035) promoted a significant increase in fracture risk independent of age and sex. Conclusions The present study indicates that disaster-induced PTSD symptoms and insomnia contribute to increased fracture risk among older adults residing in evacuation areas within the Fukushima Prefecture.


2020 ◽  
Author(s):  
Fumikazu Hayashi ◽  
Tetsuya Ohira ◽  
Hironori Nakano ◽  
Masanori Nagao ◽  
Kanako Okazaki ◽  
...  

Abstract Background Psychological stress has been known to affect bone metabolism and increase fracture risk. However, the association between post-traumatic stress disorder (PTSD) and bone fractures remains unclear. The current study aimed to clarify the effects of disaster-induced PTSD symptoms on fracture risk in older adults.Methods This study analyzed responses from 17,459 individuals aged ≥65 without a history of fractures at the time of the Great East Japan Earthquake who answered the Mental Health and Lifestyle Survey component of the Fukushima Health Management Survey conducted in 2011. Obtained data were able to determine the presence or absence of fractures until 2016. Age, sex, physical factors, social factors, psychological factors, and lifestyle factors were subsequently analyzed. Survival analysis was then performed to determine the relationship between each factor and fractures. Thereafter, univariate and multivariate Cox proportional hazard models were constructed to identify fracture risk factors.Results A total of 2,097 (12.0%) fractures occurred during the follow-up period. Accordingly, univariate and multivariate Cox proportional hazard models showed that PTSD symptoms (total PTSD checklists scoring ≥ 44) [hazard ratio (HR): 1.26; 95% confidence interval (CI): 1.10–1.44; P = 0.001], history of cancer (HR: 1.48; 95% CI: 1.23–1.79; P < 0.001), history of stroke (HR: 1.26; 95% CI: 1.04–1.52; P = 0.021), history of heart disease (HR: 1.30; 95% CI: 1.13–1.49; P < 0.001), history of diabetes (HR: 1.23; 95% CI: 1.09–1.39; P = 0.001), current smoking (HR: 1.27; 95% CI: 1.01–1.61; P = 0.045), and high dissatisfaction with sleep or no sleep at all (HR: 1.36; 95% CI: 1.04–1.77; P = 0.024) promoted a significant increase in fracture risk independent of age and sex.Conclusions The present study indicate that disaster-induced PTSD symptoms and insomnia could contribute to increased fracture risk among older adults residing in evacuation areas within Fukushima prefecture.


2020 ◽  
Author(s):  
Fumikazu Hayashi ◽  
Tetsuya Ohira ◽  
Hironori Nakano ◽  
Masanori Nagao ◽  
Kanako Okazaki ◽  
...  

Abstract Background Psychological stress has been known to affect bone metabolism and increase fracture risk. However, the association between post-traumatic stress disorder (PTSD) and bone fractures remains unclear. The current study aimed to clarify the effects of disaster-induced PTSD symptoms on fracture risk in older adults.Methods This study analyzed responses from 17,474 individuals aged ≥65 without a history of fractures at the time of the Great East Japan Earthquake who answered the Mental Health and Lifestyle Survey component of the Fukushima Health Management Survey conducted in 2011. Obtained data were able to determine the presence or absence of fractures until 2016. Age, sex, physical factors, social factors, psychological factors, and lifestyle factors were subsequently analyzed. Survival analysis was then performed to determine the relationship between each factor and fractures. Thereafter, univariate and multivariate Cox proportional hazard models were constructed to identify fracture risk factors.Results A total of 2,097 (12.0%) fractures occurred during the follow-up period. Accordingly, univariate and multivariate Cox proportional hazard models showed that PTSD symptoms (total PTSD checklists scoring ≥ 44) [hazard ratio (HR): 1.26; 95% confidence interval (CI): 1.10–1.44; P = 0.001], history of cancer (HR: 1.49; 95% CI: 1.24–1.79; P < 0.001), history of stroke (HR: 1.25; 95% CI: 1.03–1.52; P = 0.023), history of heart disease (HR: 1.30; 95% CI: 1.13–1.50; P < 0.001), history of diabetes (HR: 1.23; 95% CI: 1.09–1.39; P < 0.001), current smoking (HR: 1.29; 95% CI: 1.02–1.63; P = 0.036), and high dissatisfaction with sleep or no sleep at all (HR: 1.33; 95% CI: 1.02–1.74; P = 0.035) promoted a significant increase in fracture risk independent of age and sex.Conclusions The present study indicates that disaster-induced PTSD symptoms and insomnia contribute to increased fracture risk among older adults residing in evacuation areas within Fukushima Prefecture.


2019 ◽  
pp. 088626051987602
Author(s):  
Hannah J. Holmes ◽  
Kelsey J. Sala-Hamrick ◽  
Sheri E. Pegram ◽  
Eleshia K. Evans ◽  
Jaclyn Wilton-Martindale ◽  
...  

Women’s self-defense training increases self-efficacy and reduces subsequent assaults, but self-defense training’s effects on women’s psychological and interpersonal functioning are understudied, particularly for women with histories of interpersonal victimization. This study examined the effects of a self-defense course on somatic symptoms, post-traumatic stress symptoms, depression, anxiety, interpersonal problems, and locus of control among women with and without interpersonal victimization histories and explored how women’s disinhibition of their aggression during simulated attacks predicts changes in their symptoms and functioning. In all, 82 women reported their symptoms and functioning before participation and 6 weeks after participation in a university-based Rape Aggression Defense course. Among the whole sample, participation in the course led to significantly decreased posttraumatic stress, somatic, and hostility symptoms and problems with being too nonassertive, overly accommodating, and self-sacrificing. Women who reported interpersonal victimization histories ( n = 49) did not differ in the degree of improvements when compared with women without interpersonal victimization histories ( n = 33). Greater disinhibition during the simulation predicted less improvement in some symptoms; moderation analyses showed that this association occurred only among those women with high baseline anxiety or hostility. These findings highlight the value of self-defense training in improving the health of women, including posttraumatic stress symptoms and interpersonal functioning, regardless of women’s history of interpersonal victimization. Results also suggest the importance of considering women’s baseline symptoms in modulating the degree of aggression that is optimally expressed during training.


2020 ◽  
Author(s):  
Fumikazu Hayashi ◽  
Tetsuya Ohira ◽  
Hironori Nakano ◽  
Masanori Nagao ◽  
Kanako Okazaki ◽  
...  

Abstract Background It has been reported that psychological stress affects bone metabolism and increases the risk of fracture. However, the relationship between bone fractures and post-traumatic stress disorder (PTSD) is unclear. This study aimed to evaluate the effects of disaster-induced PTSD symptoms on fracture risk in older adults.Methods This study evaluated responses from 17,474 individuals aged ≥65 years without a history of fractures during the Great East Japan Earthquake who answered the Mental Health and Lifestyle Survey component of the Fukushima Health Management Survey conducted in 2011. The obtained data could determine the presence or absence of fractures until 2016. Age, sex, physical factors, social factors, psychological factors, and lifestyle factors were subsequently analyzed. Survival analysis was then performed to determine the relationship between the fractures and each factor. Thereafter, univariate and multivariate Cox proportional hazard models were constructed to identify fracture risk factors.Results In total, 2,097 (12.0%) fractures were observed throughout the follow-up period. Accordingly, univariate and multivariate Cox proportional hazard models showed that PTSD symptoms (total PTSD checklists scoring ≥ 44) [hazard ratio (HR): 1.26; 95% confidence interval (CI): 1.10–1.44; P = 0.001], history of cancer (HR: 1.49; 95% CI: 1.24–1.79; P < 0.001), history of stroke (HR: 1.25; 95% CI: 1.03–1.52; P = 0.023), history of heart disease (HR: 1.30; 95% CI: 1.13–1.50; P < 0.001), history of diabetes (HR: 1.23; 95% CI: 1.09–1.39; P < 0.001), current smoking (HR: 1.29; 95% CI: 1.02–1.63; P = 0.036), and high dissatisfaction with sleep or no sleep at all (HR: 1.33; 95% CI: 1.02–1.74; P = 0.035) promoted a significant increase in fracture risk independent of age and sex.Conclusions The present study indicates that disaster-induced PTSD symptoms and insomnia contribute to increased fracture risk among older adults residing in evacuation areas within the Fukushima Prefecture.


Medicina ◽  
2020 ◽  
Vol 57 (1) ◽  
pp. 2
Author(s):  
Paola Longo ◽  
Enrica Marzola ◽  
Carlotta De Bacco ◽  
Matilde Demarchi ◽  
Giovanni Abbate-Daga

Background and Objectives: Anorexia nervosa (AN) is a complex disorder whose etiopathogenesis involves both biological and environmental factors. The aims of the present study were to retrospectively analyze risk factors in young patients with AN and to assess differences in clinical and eating-related symptoms between patients with and without a diagnosis of post-traumatic stress disorder (PTSD) and with or without a history of acknowledged risk factors. Materials and Methods: Sixty-four patients with AN (<25 years old) were recruited and completed an anamnestic evaluation and the following self-report measures: Eating Disorder Examination Questionnaire (EDE-Q), Childhood Trauma Questionnaire (CTQ), State-Trait Anxiety Inventory (STAI-Y), Beck Depression Inventory (BDI), Life Events Checklist (LEC), and Dissociative Experience Scale (DES). The PTSD diagnosis was assigned according to the Structured Clinical Interview for the DSM-5 (SCID-5). Results: The most frequent risk factors were those associated with relational traumatic events and familiarity for psychiatric disorders. Higher severity of body-related symptoms (i.e., those symptoms impacting on body image and perception and leading to body concerns) emerged in patients with PTSD, versus patients without PTSD diagnosis; however, after controlling for dissociative symptoms, only differences in BMI remained significant. Concerning other risk factors, those with a history of childhood trauma were more depressed than patients without such history and those with familiarity with eating disorders reported more AN-related hospitalizations in the past than those individuals without familiarity. Conclusion: These results suggest the importance of investigating the presence of risk factors and PTSD diagnosis in patients with AN, and to treat post-traumatic symptoms in young patients in order to decrease the risk of developing severe forms of AN. Moreover, a particular focus on those patients with a family member affected by an eating disorder could be of clinical utility.


Author(s):  
Susanne Fischer ◽  
Tabea Schumacher ◽  
Christine Knaevelsrud ◽  
Ulrike Ehlert ◽  
Sarah Schumacher

Abstract Background Less than half of all individuals with post-traumatic stress disorder (PTSD) remit spontaneously and a large proportion of those seeking treatment do not respond sufficiently. This suggests that there may be subgroups of individuals who are in need of augmentative or alternative treatments. One of the most frequent pathophysiological findings in PTSD is alterations in the hypothalamic–pituitary–adrenal (HPA) axis, including enhanced negative feedback sensitivity and attenuated peripheral cortisol. Given the role of the HPA axis in cognition, this pattern may contribute to PTSD symptoms and interfere with key processes of standard first-line treatments, such as trauma-focused cognitive behavioural therapy (TF-CBT). Methods This review provides a comprehensive summary of the current state of research regarding the role of HPA axis functioning in PTSD symptoms and treatment. Results Overall, there is preliminary evidence that hypocortisolaemia contributes to symptom manifestation in PTSD; that it predicts non-responses to TF-CBT; and that it is subject to change in parallel with positive treatment trajectories. Moreover, there is evidence that genetic and epigenetic alterations within the genes NR3C1 and FKBP5 are associated with this hypocortisolaemic pattern and that some of these alterations change as symptoms improve over the course of treatment. Conclusions Future research priorities include investigations into the role of the HPA axis in day-to-day symptom variation, the time scale in which biological changes in response to treatment occur, and the effects of sex. Furthermore, before conceiving augmentative or alternative treatments that target the described mechanisms, multilevel studies are warranted.


2021 ◽  
pp. 088626052110219
Author(s):  
Matthew M. Yalch ◽  
Sloane R. M. Rickman

Intimate partner violence (IPV) is a common problem for women in the United States and is associated with symptoms of post-traumatic stress disorder (PTSD) as well as hazardous use of substances like alcohol and drugs. However, not all subtypes of IPV (i.e., physical, sexual, and psychological) are equally predictive of PTSD and hazardous substance use. Although previous research suggests that psychological IPV has the strongest relative effect on PTSD symptoms and substance use, there is less research on IPV subtypes’ cumulative effects. In this study, we examined the relative and cumulative effects of physical, sexual, and psychological IPV on PTSD symptoms and hazardous substance use in a sample of women in the United States recruited via Amazon’s Mechanical Turk ( N = 793) using bootstrapped multiple regression and configural frequency analyses. Results suggest that physical IPV had the most pronounced influence (medium-large effect sizes) on substance use across women, but that the cumulative effects of all three IPV subtypes were most closely associated with diagnostic levels of both PTSD and substance use at the level of groups of women. These findings clarify and extend previous research on the differential effects of IPV subtypes and provide directions for future research and clinical intervention.


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