Verruciform Xanthoma of the Esophagus: Two Case Reports With Review of the Literature

2019 ◽  
Vol 28 (3) ◽  
pp. 302-305
Author(s):  
Hirotsugu Noguchi ◽  
Ikumi Kitazono ◽  
Kazumasa Hamada ◽  
Takako Tanaka ◽  
Takashi Tasaki ◽  
...  

Verruciform xanthoma is a rare benign verrucopapillary lesion that develops in the oral mucosa and genital skin. Its development in the esophagus is extremely rare, with only 5 reported cases. We present 2 cases of verruciform xanthoma of the esophagus. Case 1 involved a 91-year-old woman, who had hypertension and chronic gastritis with Helicobacter pylori infection, with a 12-year history of a 10-mm white-yellow elevated lesion on the esophagus, 35 cm from the incisor teeth. Case 2 involved a 70-year-old man with fundic gland polyp, hyperlipidemia, and lung cancer, who had a 10-mm whitish granular/verrucoid lesion on the esophagus, 28 cm from the incisor teeth. Microscopically, these lesions show verrucous and papillomatous epithelial hyperplasia with neutrophilic intraepithelial exocytosis. The histological hallmark is the presence of numerous foamy histiocytes infiltrating the elongated squamous epithelial papillae. Although its etiology is unknown, irritation or trauma caused by radiotherapy has been suggested.

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 998
Author(s):  
Chiara Lazzari ◽  
Aurora Mirabile ◽  
Alessandra Bulotta ◽  
Maria Grazia Viganó ◽  
Francesca Rita Ogliari ◽  
...  

Several trials have tried for decades to improve the outcome of extensive disease small cell lung cancer (ED-SCLC) through attempts to modify the standard treatments. Nevertheless, platinum/etoposide combination and topotecan have remained respectively the first and the second line standard treatments for the last 40 years. With the advent of immunotherapy, this scenario has finally changed. Our review aims to provide an overview of the primary studies on the actual therapeutic strategies available for ED-SCLC patients, and to highlight emerging evidence supporting the use of immunotherapy in SCLC patients.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Nour Abdul Halim ◽  
Imad Uthman ◽  
Rayan Rammal ◽  
Hazem I. Assi

Idiopathic granulomatous mastitis is a rare benign inflammatory breast disease that affects women of childbearing age with a history of breastfeeding. It usually presents as an enlarging breast mass that can greatly mimic breast cancer. Moreover, it does not have a specific radiographic finding, so the only way to reach a definitive diagnosis is by core biopsy and histology. Furthermore, a consensus regarding the best treatment modality has not been reached yet. In this report, we describe the cases of two patients who suffered from this disease, and to our knowledge, such a report is the first of its kind to address this topic in this region. Therefore, because of its uncommon nature and obscure presentation, we hereby report two cases of idiopathic granulomatous mastitis. The clinical presentation, treatment, and pathological findings are described, and a literature review on idiopathic granulomatous mastitis will be reported.


2019 ◽  
Vol 35 (7) ◽  
pp. 1158-1162
Author(s):  
Takumi Notsu ◽  
Kyoichi Adachi ◽  
Tomoko Mishiro ◽  
Norihisa Ishimura ◽  
Shunji Ishihara

2011 ◽  
Vol 23 (2) ◽  
pp. 182-186 ◽  
Author(s):  
Shuhei Tazaki ◽  
Fumihiko Nozu ◽  
Nozomi Yosikawa ◽  
Michio Imawari ◽  
Naoto Suzuki ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Doğan Atılgan ◽  
Yusuf Gençten

Carcinosarcoma of the urinary bladder is a rare neoplasm that is composed of malignant epithelial and mesenchymal components. In these tumors, histogenesis and biological behaviour remain controversial. Approximately 70 cases have been reported in the literature, usually as case reports or a small series. A series of 221 cases using the Surveillance, Epidemiology and End Results (SEER) Program database has been reported recently. Optimal treatment is uncertain. Herein, we report a case of sarcomatoid carcinoma of urinary bladder of a farmer aged 84 years old with a year history of hematuria and dysuria. A transurethral resection of the tumor (TUR-T) revealed a carcinosarcoma. The patient underwent radical cystectomy, and there is no tumor recurrence for 15 months after treatments.


Vascular ◽  
2011 ◽  
Vol 19 (1) ◽  
pp. 42-46 ◽  
Author(s):  
Derek P Nathan ◽  
Grace J Wang ◽  
Edward Y Woo ◽  
Ronald M Fairman ◽  
Benjamin M Jackson

Hepatic artery aneurysms (HAAs) represent a complex and often lethal condition. An 80-year-old woman with polyarteritis nodosa and a right hepatic lobe HAA underwent endovascular repair with coils. Her case was complicated by intraoperative HAA rupture requiring exploratory laparotomy. In the second case, a 37-year-old man with a large HAA underwent open repair with a bifurcated graft that extended from the common hepatic artery to the left and right hepatic arteries. These two cases highlight the difficulty of managing HAAs, and provide insight into their treatment. Furthermore, our review of the literature highlights the data on the management of HAAs, including the natural history of this disease process, the indications for repair and the optimal treatment modality.


2001 ◽  
Vol 10 (6) ◽  
pp. 426-432 ◽  
Author(s):  
K. Mujaibel ◽  
A. Benjamin ◽  
M.-F. Delisle ◽  
K. Williams

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xi Tang ◽  
Gang Liu ◽  
Xianglan Tan ◽  
Chengjun Liu ◽  
Jin Xiang ◽  
...  

Abstract Background Lung cancer associated with cystic airspaces, especially solitary multicystic lesion lung cancer, is a rare disease (a rare imaging performance of non-small cell lung cancer). It is difficult to diagnose owing to the lack of a clear definition; therefore, diagnosis of these neoplastic lesions remains challenging. Case presentation We outlined two cases of elderly Chinese men who were admitted to the hospital with a solitary multicystic lesion of the lung and subsequent surgical resection, confirming a diagnosis of adenocarcinoma. Conclusions For solitary pulmonary cystic airspaces (especially solitary multicystic lung lesions), it is important to properly recognise their imaging features. Due to the possibility of malignancies, timely surgery is an effective treatment strategy for early diagnosis.


Cephalalgia ◽  
2010 ◽  
Vol 30 (8) ◽  
pp. 975-982 ◽  
Author(s):  
Sanjay Prakash ◽  
Nilima D Shah ◽  
Bhavna V Chavda

Introduction: Response to indomethacin is an essential feature for the diagnosis of both paroxysmal hemicrania (PH) and hemicrania continua (HC). Cluster headache (CH) is widely considered to be a disease unresponsive to indomethacin. Case reports: We report four patients with CH who responded to indomethacin. Two patients, who were refractory to the usual therapy for CH, fulfilled the criteria for chronic CH. Conversely, two patients had a history of episodic CH and showed response to both indomethacin and the usual therapy for CH. Literature review: We also reviewed the literature for the presence of indomethacin response in patients with CH. We noted a large number of cases labeled as CH by the authors which showed a response to indomethacin. Discussion: Many cases of definite or possible CH were wrongly labeled as PH because of patients' responding to indomethacin. Conclusion: The response to indomethacin in patients with CH may not be as immediate as in other indomethacin-responsive headaches, and many patients may need larger doses.


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