Sebaceous Carcinoma of the Breast: Fact or Fiction? A Case Report and a Review of the Literature

2020 ◽  
pp. 106689692093778
Author(s):  
Ludovica De Vincentiis ◽  
Maria Paola Mariani ◽  
Anna Maria Cesinaro ◽  
Anna Maria Dalena ◽  
Gerardo Ferrara
Keyword(s):  
Breast Carcinoma ◽  
Needle Aspiration ◽  
Sebaceous Carcinoma ◽  
World Health ◽  
Positive Staining ◽  
Carcinoma Of The Breast ◽  
Aspiration Cytology ◽  
Clear Cut ◽  
Needle Aspiration Cytology ◽  
Health Organization

Introduction. Previously considered an exceedingly rare entity, sebaceous carcinoma of the breast is now regarded in the World Health Organization 2019 classification as a “special histopathological pattern” of invasive breast carcinoma of no special type. Case Description. In this article, we report the case of a fine needle aspiration cytology and the histopathological features of a breast carcinoma with clear-cut morphological features suggesting sebaceous differentiation, but showing no positive staining with the anti-adipophilin antibody. Conclusions. A morphologically clear-cut sebaceous differentiation is not invariably associated with adipophilin positivity; moreover, in breast carcinoma, adipophilin positivity does not automatically imply sebaceous differentiation. At present, immunomorphological evidence for the recognition of sebaceous carcinoma as a “special type” breast carcinoma subtype is too weak.

scholarly journals Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis

Rare Tumors ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 172-174 ◽  
Author(s):  
Rehab M. Samaka ◽  
Mona A. Kandil
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Soft Tissues ◽  
Pelvic Mass ◽  
Needle Aspiration ◽  
World Health ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Health Organization

Parachordoma is an extremely rare soft tissue tumor of unknown lineage. Parachordoma develops most often on the extremities. Only 2 cases have been reported as pelvic parachordoma. A 46-year old Egyptian woman with a huge painful pelvic mass was found to have a parachordoma with ectopic pelvic right kidney. There is only one report in the literature of fine needle aspiration cytology in this setting. The microscopic picture of parachordoma is not new to pathologists but the gross picture of this rare tumor has not previously been published; not even in the World Health Organization classification of soft tissues tumors. Diagnosis was confirmed by immunohistochemistry. The patient is in good clinical condition without any evidence of recurrence or metastasis after 84 months of follow up.

Correlation of Ultrasound Findings and Fine-Needle Aspiration Cytology for the Diagnosis of Axillary Lymph Node Metastasis in Patients with Breast Carcinoma

2018 ◽  
Vol 63 (1) ◽  
pp. 17-22
Author(s):  
Kusum Kapila ◽  
Preetha Alath ◽  
Govind H. Hebbar ◽  
Mohammed Jaragh ◽  
Sara S. George ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Width Ratio ◽  
Axillary Lymph ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Length Width ◽  
Needle Aspiration Cytology

Objective: Ultrasound-guided fine-needle aspiration cytology (USG-FNAC) is used for the detection of axillary lymph node (ALN) metastasis in patients with breast carcinoma (BC). US findings have a good diagnostic accuracy with high sensitivity and specificity. The aim of this study is to correlate the detection of ALN metastases on US with FNAC in BC patients. Study Design: In 75 BC patients, over a period of 9 months (January to September 2017), the size, cortical thickness (CT), presence or absence of hilar fat, and length/width ratio of ALN on US were reviewed and correlated with FNAC findings. Results: The age range was 29–78 (mean 52) years. There were 38 patients with a single ALN and 37 with multiple ALNs. ALNs with a maximum length of > 2.5 cm were malignant in 100% of cases while those ≥1.5 cm were malignant in 80.4%. ALNs with a CT of > 3 mm had metastasis in 78.1% cases. ALNs with absent hilar fat showed tumour in 87.5% cases. A length/width ratio of < 2 showed a metastatic tumour in 66.7% of aspirates. Conclusion: An association was seen between metastatic carcinoma on FNAC and axillary US features of a maximum length of ≥1.5 cm, the absence of hilar fat, and a CT of > 3 mm (p < 0.05).

Fine needle aspiration cytology of solid neuroendocrine carcinoma of the breast: A case report

2010 ◽  
Vol 39 (7) ◽  
pp. 527-530 ◽  
Author(s):  
Namiki Kawanishi ◽  
Yoshiaki Norimatsu ◽  
Mahito Funakoshi ◽  
Toshiaki Kamei ◽  
Hiroshi Sonobe ◽  
...  
Keyword(s):  
Case Report ◽  
Neuroendocrine Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Carcinoma Of The Breast ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Fine-Needle Aspiration Cytology in the Diagnosis of Breast Paraffinoma

2021 ◽  
pp. 1-5
Author(s):  
Kenneth Y.Y. Kok ◽  
Pemasiri Upali Telisinghe ◽  
Sonal Tripathi
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Diagnostic Procedures ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Multinucleated Giant Cells ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

<b><i>Introduction:</i></b> Paraffin injections for breast augmentation once a popular form of mammoplasty are now considered obsolete. It had been abandoned by clinicians because of its associated serious complications. The practice is however still available and is being practiced by nonmedically qualified people. Paraffin injection results in the formation of multiple foreign-body granulomas known as breast paraffinoma. The clinical features of breast paraffinoma can mimic and be mistaken for breast carcinoma or inflammatory breast carcinoma. The use of fine-needle aspiration cytology (FNAC) in the evaluation of patients with breast paraffinoma has not been fully evaluated. <b><i>Methods:</i></b> Retrospective review was performed on 30 patients who presented with breast paraffinoma between June 1, 2010, and June 30, 2020, who also had FNAC as part of their breast lump evaluation. <b><i>Results:</i></b> FNAC of 73.3% patients showed multinucleated giant cells and macrophages or histiocytes containing engulfed clear, empty intracytoplasmic vacuoles of varying sizes. In 13.3% of the patients, macrophages or histiocytes with engulfed clear intracytoplasmic vacuoles of varying sizes were seen. In 6.7% of patients, multinucleated giant cells containing engulfed vacuoles of varying sizes were seen, and in 6.7% of patients, hypocellular smears with large amount of clear spaces were seen. Oily droplets were seen in the background of all the smears, and there were no malignant cells seen. These features were compatible with breast paraffinoma. <b><i>Conclusion:</i></b> Most patients with breast paraffinoma can be managed conservatively and they do not require further treatment; FNAC with its characteristic features can provide the reliable diagnosis of breast paraffinoma and therefore sparing these patients from more invasive diagnostic procedures.

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