Efficacy of antiviral chemotherapy for retrovirus-infected cats

Global importance:The two feline retroviruses, feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), are global and widespread, but differ in their potential to cause disease.Viral infection – FIV:FIV, a lentivirus that shares many properties with human immunodeficiency virus (HIV), can cause an acquired immune deficiency syndrome, which predisposes cats to other infections, stomatitis, neurological disorders and tumours. Although secondary infections are common, specific opportunistic infections or acquired immunodeficiency virus-defining infections, such as those that occur with HIV, are not commonly reported in FIV-infected cats. In most naturally infected cats, FIV does not cause a severe clinical syndrome; with appropriate care, FIV-infected cats can live many years before succumbing to conditions unrelated to their FIV infection. Thus, overall survival time is not necessarily shorter than in uninfected cats, and quality of life is usually high over many years or lifelong.Viral infection – FeLV:FeLV, an oncornavirus, is more pathogenic than FIV. Historically, it was considered to account for more disease-related deaths and clinical syndromes in cats than any other infectious agent. Recently, the prevalence and importance of FeLV have been decreasing, mainly because of testing and eradication programmes and the use of FeLV vaccines. Progressive FeLV infection can cause tumours, bone marrow suppression and immunosuppression, as well as neurological and other disorders, and leads to a decrease in life expectancy. However, with appropriate care, many FeLV-infected cats can also live several years with a good quality of life.Practical relevance:A decision regarding treatment or euthanasia should never be based solely on the presence or absence of a retrovirus infection. Antiviral chemotherapy is of increasing interest in veterinary medicine, but is still not used commonly.Evidence base:This article reviews the current literature on antiviral chemotherapy in retrovirus-infected cats, focusing on drugs that are currently available on the market and, thus, could potentially be used in cats.

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Influence of physical exercise on practice standards morphofunctional, immune function and quality of elderly with aids: case study.

Manual Therapy Posturology & Rehabilitation Journal ◽

10.17784/mtprehabjournal.2014.12.176 ◽

2014 ◽

Vol 12 ◽

pp. 176

Author(s):

Ana Paula Serra De Araújo ◽

José Alípio Garcia Gouvêa ◽

Joaquim Martins Junior ◽

Dennis Armando Bertolini ◽

Sônia Maria Marques Gomes Bertoline

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Elderly Patients ◽

Immune Function ◽

Exercise Intervention ◽

Opportunistic Infections ◽

Elderly Women ◽

Infected Individual ◽

Immunodeficiency Virus

Introduction: Acquired Immunodeficiency Syndrome (AIDS) is an infectious disease caused by the human immunodeficiency virus (HIV) that causes progressive immunodeficiency virus, rendering the infected individual susceptible to opportunistic infections and diseases. Your clinical treatment is basically medicine and brings with it a number of side effects among which stands out the development of muscle fatigue, lipodystrophy and decreased quality of life. In order to improve the quality of life of people with AIDS, researchers have investigated what kind of benefits to the practice of activity can bring to these individuals. Objective: To evaluate the influence of physical activity on the morphofunctional supervised patterns, immune function and quality of life of elderly patients with AIDS. Method: A descriptive study in which volunteers participated in 4 elderly women with AIDS, who underwent a program of physical activity lasting 16 weeks. Results: The results showed that the proposed program of physical activity was beneficial to functional morphology patterns, immune function and quality of life in older study participants. Conclusion: Sixteen weeks of exercise intervention targeted to elderly patients with AIDS are beneficial, because they promote improvements in the components of morphofunctional standards, with emphasis on flexibility and muscle strength as well as possible changes in markers of immune function and quality domains of life.

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Dukungan sosial dan kualitas hidup orang dengan HIV/AIDS

Berita Kedokteran Masyarakat ◽

10.22146/bkm.12563 ◽

2017 ◽

Vol 33 (3) ◽

pp. 147

Author(s):

Mardia Mardia ◽

Riris Andono Ahmad ◽

Bambang Sigit Riyanto

Keyword(s):

Quality Of Life ◽

Social Support ◽

Antiretroviral Therapy ◽

Social Life ◽

Opportunistic Infections ◽

People Living With Hiv ◽

Hiv Diagnosis ◽

Criteria For Diagnosis ◽

Hiv Aids

Purpose: This study aimed to determine the quality of life among people living with HIV/AIDS based on the criteria for diagnosis and other factors.Methods: This study was conducted in the VCT clinic hospital of Dr. Moewardi. The population was HIV-positive patients with antiretroviral therapy. Data collection conducted through medical records and interview to patients. Results: Out of a total of 89 respondents, 66.29% were males and 71.91% were aged between 26-45 years. We found significant correlations for diagnosis of HIV/AIDS, opportunistic infections, time since HIV diagnosis, duration of ARV therapy, social support, modes of transport, sex, age, and marital status with the quality of life. Multivariate analysis obtained by each variable showed the strongest association with the quality of life was time since diagnosis, social support and duration of ARV therapy. Conclusion: The quality of life was better for those who have been diagnosed with HIV/AIDS ≥ 32 months, with social support, and who have been undergoing antiretroviral therapy ≥ 29 months. Improved counseling in the early days of ARV therapy is necessary to always maintain the treatment and provide support for their social life.

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Surgical management of hypothalamic hamartomas in patients with gelastic epilepsy

Neurosurgical FOCUS ◽

10.3171/foc/2008/25/9/e8 ◽

2008 ◽

Vol 25 (3) ◽

pp. E8 ◽

Cited By ~ 16

Author(s):

Bassam Addas ◽

Elisabeth M. S. Sherman ◽

Walter J. Hader

Keyword(s):

Quality Of Life ◽

Epileptic Encephalopathy ◽

Clinical Syndrome ◽

Seizure Freedom ◽

Interstitial Radiotherapy ◽

Hypothalamic Hamartomas ◽

Surgical Options ◽

Gelastic Epilepsy ◽

Refractory Seizures

Gelastic epilepsy (GE) associated with hypothalamic hamartomas (HHs) is now a well-characterized clinical syndrome consisting of gelastic seizures starting in infancy, medically refractory seizures with or without the development of multiple seizure types, and behavioral and cognitive decline. It has been postulated that the development of the HH-GE syndrome is a result of a progressive epileptic encephalopathy or secondary epileptogenesis, which is potentially reversible with treatment of the HH. A variety of surgical options for the treatment of HHs exist, including open and endoscopic procedures, radiosurgery, interstitial radiotherapy, and stereotactic radiofrequency thermocoagulation. Surgical treatment can result in seizure freedom in up to 50% of patients and can be accompanied by significant improvements in behavior, cognition, and quality of life. Partial treatment of HHs may be sufficient to reduce seizure frequency and improve behavior and quality of life with less risk. A component of reversible cognitive dysfunction may be present in some patients with an HH-GE syndrome.

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Associations among depression, suicidal behavior, and quality of life in patients with human immunodeficiency virus

World Journal of Virology ◽

10.5501/wjv.v4.i3.303 ◽

2015 ◽

Vol 4 (3) ◽

pp. 303 ◽

Cited By ~ 15

Author(s):

Gianluca Serafini

Keyword(s):

Quality Of Life ◽

Human Immunodeficiency Virus ◽

Suicidal Behavior ◽

Immunodeficiency Virus

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Quality of life of patients infected with human immunodeficiency virus (HIV)

Medycyna Ogólna i Nauki o Zdrowiu ◽

10.26444/monz/122379 ◽

2020 ◽

Vol 26 (2) ◽

pp. 169-174

Author(s):

Edyta Kamińska-Otok

Keyword(s):

Quality Of Life ◽

Human Immunodeficiency Virus ◽

Immunodeficiency Virus

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Herpes Zoster involving Trigeminal Nerve

Journal of Contemporary Dentistry ◽

10.5005/jcd-2-1-50 ◽

2012 ◽

Vol 2 (1) ◽

pp. 50-52

Author(s):

Rohit B Gadda ◽

Neha Patil ◽

Rohini Salvi

Keyword(s):

Quality Of Life ◽

Herpes Zoster ◽

Viral Infection ◽

Varicella Zoster Virus ◽

Acute Pain ◽

Healthy Male ◽

Prodromal Symptoms ◽

Varicella Zoster ◽

Acute Viral Infection

Abstract Herpes zoster is a common acute viral infection caused by reactivation of Varicella-Zoster virus. Acute pain of herpes zoster lowers the quality of life and interferes with day to day activities. We report a case of herpes zoster in a 68 year old, healthy male patient in which the prodromal symptoms started as toothache. This case highlights the importance of a thorough dental history and examination in patients with toothache.

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Gynaecology and genitourinary medicine

Oxford Assess and Progress: Clinical Specialties ◽

10.1093/oso/9780198802907.003.0014 ◽

2018 ◽

Author(s):

Kevin Hayes

Keyword(s):

Quality Of Life ◽

Sexual Health ◽

Teenage Pregnancy ◽

Full Spectrum ◽

Sexually Transmitted ◽

Immunodeficiency Virus ◽

The Government ◽

The Uk ◽

Improve Access

Gynaecological practices are changing constantly, with more emphasis on management in primary care, conservative, rather than surgical, management of conditions, and an increase in sub-specialization such as gynaecological oncology and urogynaecology. This chapter reflects these changes and covers the commonest areas in this interesting field. Sexual health is a specialty in its own right. The number of cases of sexually transmitted infections are rising in the UK, despite efforts to raise awareness of safe sex, so knowledge of their presentations is important. The UK also has the highest rate of teenage pregnancy in Europe, and the Government has set targets to improve access to contraceptive advice for women. In recent years, astounding advances have been made in the treatment of human immunodeficiency virus (HIV) infection, and people with HIV can now expect to have a much better quality of life. Although this chapter primarily focuses on diseases affecting women, we have included questions on the sexual health of men to represent the full spectrum of sexual health practice.

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