The clinical outcome of the Metha short hip stem: a systematic scoping review

2020 ◽  
pp. 112070002090371 ◽  
Author(s):  
Michael-Alexander Malahias ◽  
Purnachandra Tejaswi ◽  
Dimitrios Chytas ◽  
Vikram Kadu ◽  
Dimitrios Karanikas ◽  
...  

Introduction: Short femoral stems were designed to bridge the gap between conventional straight design stems and hip resurfacing prostheses in total hip arthroplasty (THA). A number of clinical trials have been recently conducted to assess the clinical and safety profile of the cementless, colarless, tapered Metha short hip stem in young or active middle-aged individuals. Methods: A systematic scoping review was conducted according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. 4 reviewers independently conducted the search using the MEDLINE/PubMed database and the Cochrane Database of Systematic Reviews. These databases were queried with the terms “short” AND “hip” AND “stem”. Results: From the initial 773 studies we finally chose 12 studies after applying our inclusion-exclusion criteria. The number of operated hips that were included in these studies was 5048 (mean BMI range: 22.7–35.2, mean age range: 44.4–60.4 years, mean follow-up range: 2–9 years). The mean modified Coleman methodology score was 52.3/100, while it ranged from 31/100 to 63/100. All mean clinical outcome scores that were used in the studies illustrated significant postoperative improvement when compared with the respective initial values. The revision rate of the Metha stem for component-related reasons was 2.5%, while the rate of major complications not requiring revision of the Metha stem was 2.8%. Conclusions: The Metha stem performs well in young or active middle-aged THA patients. Further studies are required for the assessment of the long-term results.

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
Michael-Alexander Malahias ◽  
Lazaros Kostretzis ◽  
Panayiotis D. Megaloikonomos ◽  
Erwin-Brian Cantiller ◽  
Dimitrios Chytas ◽  
...  

This study was performed to determine whether Autologous Matrix-Induced Chondrogenesis (AMIC) is an effective and safe treatment option for patients with symptomatic Osteochondral defects of the Talus (OCTs) and to identify factors that influence the clinical outcome. A systematic review of the literature was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Three reviewers independently conducted the literature search using the MEDLINE/PubMed database and the Cochrane Database of Systematic Reviews. The databases were queried using the terms “autologous” AND “matrix” AND “induced” AND “chondrogenesis.” Thirteen studies were eligible for review. All studies that compared the preoperative and postoperative mean values of different clinical/functional scores showed significant clinical improvement. The final postoperative mean Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score ranged from 50.9 to 74.5. The included studies indicated that age and body mass index may have a detrimental impact on the postoperative outcome. A higher re-intervention rate is expected with the open technique, mainly because of hardware removal after malleolar osteotomy. This data analysis demonstrated that both arthroscopic and open AMIC procedures are effective and safe for the treatment of OCTs. Level IV, systematic review of therapeutic studies.


2018 ◽  
Vol 9 ◽  
Author(s):  
Georgina Mullen ◽  
Gary O'Reilly

AbstractThis scoping review used social mentality theory (SMT) as a framework to identify and integrate relevant eating disorder systematic reviews and meta-analyses. A systematic search of the PsycINFO database was conducted, using terms from SMT and eating disorder literature. Eighteen systematic reviews met the inclusion criteria. Findings suggest that those with eating disorders also experience a number of relationship difficulties, in childhood and/or adulthood, related to attachment style, caregiver experiences, family functioning, social rank, social cognition, and self-compassion. The identification of these social difficulties is established in the eating disorder literature. SMT can provide a theoretical framework to understand how evolved motives to relate to others may contribute to these difficulties.


2021 ◽  
Vol 37 (5) ◽  
pp. 421-434
Author(s):  
Susana Pereira Costa ◽  
◽  
Inês Lopes Antunes ◽  
Ana Margarida Gomes ◽  
Cláudia Ho ◽  
...  

Objetivos: Resumir as informações publicadas acerca dos problemas de coagulação em adultos com SARS-CoV-2, incluindo características, fisiopatologia, diagnóstico e resposta ao uso profilático ou terapêutico de anticoagulantes ou antiagregantes plaquetários. Métodos: Realizada uma revisão abrangente, de acordo com as guidelines Joanna Briggs Institute Guidelines on Scoping Reviews e Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review guidelines (PRISMA-ScR). Efetuada pesquisa nas bases de dados MEDLINE®, SciELO® e Web of Science® entre 1 e 2 de maio de 2020. A seleção dos artigos foi dividida em etapas sequenciais considerando: título, resumo e artigo integral. Em cada etapa os artigos foram aceites ou rejeitados tendo em conta os critérios de inclusão e exclusão. Foi feito o mapeamento dos dados e a evidência relevante foi sumarizada. Resultados: Após seleção obtiveram-se 106 artigos. Destes, 36 correspondiam a cartas, 28 a estudos originais, 25 a revisões e 14 a relatos de caso; uma meta-análise, um comentário e um consenso também foram incluídos. Os resultados mostraram associação entre COVID-19 e complicações trombóticas, embora com diferentes tipos de eventos e taxas de frequência. A tríade inflamação, disfunção endotelial e coagulopatia parecem estar subjacentes às alterações fisiopatológicas. As técnicas laboratoriais e de imagem podem ser úteis para uma intervenção adequada. A profilaxia com anticoagulantes parentéricos, preferencialmente heparina de baixo peso molecular (HBPM) em dose intermédia, entre as comummente utilizadas para profilaxia ou tratamento, está indicada em pacientes hospitalizados, especialmente com doença grave. Deve ser mantida por um período variável após a alta, dependendo do doente. A anticoagulação terapêutica parece não diferir de outras situações previamente conhecidas. Conclusões: Várias incertezas persistem na abordagem dos problemas da coagulação em pacientes com infeção por SARS-CoV-2. As informações existentes dizem respeito principalmente ao contexto hospitalar e têm origem em fontes pouco robustas. Assim, são necessários ensaios clínicos aleatorizados e controlados para sustentar as decisões clínicas em todos os estadios.


Medwave ◽  
2021 ◽  
Vol 21 (02) ◽  
pp. e8144-e8144
Author(s):  
Catalina Verdejo ◽  
Luis Tapia-Benavente ◽  
Bastián Schuller-Martínez ◽  
Laura Vergara-Merino ◽  
Manuel Vargas-Peirano ◽  
...  

The increasing amount of evidence has caused an increasing amount of literature reviews. There are different types of reviews —systematic reviews are the best known—, and every type of review has different purposes. The scoping review is a recent model that aims to answer broad questions and identify and expose the available evidence for a broader question, using a rigorous and reproducible method. In the last two decades, researchers have discussed the most appropriate method to carry out scoping reviews, and recently the “Preferred Reporting Items for Systematic Reviews and Meta-Analyses’ for scoping reviews (PRISMA-ScR) reporting guideline was published. This is the fifth article of a methodological collaborative series of narrative reviews about general topics on biostatistics and clinical epidemiology. This review aims to describe what scoping reviews are, identify their objectives, differentiate them from other types of reviews, and provide considerations on how to carry them out.


2021 ◽  
Vol 10 (17) ◽  
pp. e77101724368
Author(s):  
Karla Adriana Ferreira Beckman ◽  
Marimeire Morais da Conceição ◽  
Denízia Maria Barberino Xavier Santos ◽  
Márcia Aparecida Ferreira de Oliveira ◽  
Ana Maria Fernandes Pitta

O objetivo deste estudo é mapear e analisar a produção científica acerca da auriculoterapia para crianças e adolescentes no âmbito da atenção à saúde. Para tanto, foi utilizada a estratégia PCC: (P) Participantes – Crianças e Adolescentes entre 6 e 12 anos (OMS); (C) conceito: auriculoterapia; e (C) Contexto: atenção integral à saúde, como recomendam estudiosos (Aromataris & Munn, 2020) . Que originou a seguinte questão: Quais as evidências na literatura científica sobre auriculoterapia para crianças e adolescentes no âmbito da atenção integral à saúde? Esta revisão de escopo considerará estudos originais, realizados exclusivamente com seres humanos, crianças com idade entre 6 e 12 anos incompletos, publicados na íntegra em periódicos nacionais e internacionais, gratuitos ou não, com abordagem qualitativa e/ou quantitativa, nos idiomas português, inglês e espanhol. Os estudos deverão abordar o uso da auriculoterapia na atenção à saúde. Assim, serão considerados os estudos com as variações de recursos da auriculoterapia (sementes de vaccaria, esferas magnéticas e cristais). As fontes indexadas que serão utilizadas para a revisão de escopo são: Medical Literature Anallysis and Retrieval System online (MEDLINE); Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS); Scientific Electronic Library online (SCIELO); as bases de dados Cochrane Database of Systematic Reviews (CDCR), a Bibliografia Brasileira de Odontologia (BBO), bem como a Biblioteca Virtual em Saúde em Medicinas Tradicionais, Complementar e Integrativa (BVS MTCI), Biblioteca Virtual em Saúde do Adolescente (ADOLEC) e Physiotherapy Evidence Database (PEDro). Para pesquisar a literatura cinzenta, será consultada a Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). As buscas nestas fontes indexadas serão realizadas no período entre fevereiro e março de 2022. Espera-se com esta revisão contribuir com o estado da arte acerca da produção e implementação de Práticas Integrativas Complementares.


2020 ◽  
Vol 33 (1) ◽  
pp. 49 ◽  
Author(s):  
Joana Tendais Almeida ◽  
Ana Luísa Esteves ◽  
Filipa Martins ◽  
Isabel Palma

Introduction: Statins are among the most effective drugs in lowering cholesterol levels and, consequently, in reducing cardiovascular mortality and morbidity. Although generally well tolerated, they have adverse effects that may reduce patient adherence to therapy. The objective of this evidence-based review is to summarize the evidence on the effectiveness of alternative management strategies in patients with intolerance to statins.Material and Methods: A literature search including clinical practice guidelines, systematic reviews and meta-analyses was conducted, in January 2017, in major international databases, and considered articles published in the last 10 years. The search was complemented with research papers published over the past three years and found in the PubMed database. The level of evidence and strength of recommendation were determined using the scale Strength of Recommendation Taxonomy - SORT.Results: We included eight guidelines, six systematic reviews and one research paper.Discussion: The strategies proposed by the different studies vary according to the severity of symptoms of intolerance including maintenance of the statin therapy (dose reduction, addition of a statin of equal or lower intensity or alternate days’ uptake) and lipid-lowering therapy with other drugs (ezetimibe monotherapy or association with statin tolerated dose). Supplementation with coenzyme Q10 or vitamin D, in order to improve adherence to treatment with statins, is not recommended.Conclusion: This review highlights some alternatives to address patients’ intolerance to statins; however, these are mostly based on recommendations with low to moderate evidence. Therefore, further research with randomized studies involving greater number of patients is required, in order to obtain a more robust recommendation.


2020 ◽  
pp. 219256822090681 ◽  
Author(s):  
Muthu Sathish ◽  
Ramakrishnan Eswar

Study Design: Systematic review. Objectives: To assess the methodological quality of systematic reviews and meta-analyses in spine surgery over the past 2 decades. Materials and Methods: We conducted independent and in duplicate systematic review of the published systematic reviews and meta-analyses between 2000 and 2019 from PubMed Central and Cochrane Database pertaining to spine surgery involving surgical intervention. We searched bibliographies to identify additional relevant studies. Methodological quality was evaluated with AMSTAR score and graded with AMSTAR 2 criteria. Results: A total of 96 reviews met the eligibility criteria, with mean AMSTAR score of 7.51 (SD = 1.98). Based on AMSTAR 2 criteria, 13.5% (n = 13) and 18.7% (n = 18) of the studies had high and moderate level of confidence of results, respectively, without any critical flaws. A total of 29.1% (n = 28) of the studies had at least 1 critical flaw and 38.5% (n = 37) of the studies had more than 1 critical flaw, so that their results have low and critically low confidence, respectively. Failure to analyze the conflict of interest of authors of primary studies included in review and lack of list of excluded studies with justification were the most common critical flaw. Regression analysis demonstrated that studies with funding and studies published in recent years were significantly associated with higher methodological quality. Conclusion: Despite improvement in methodological quality of systematic reviews and meta-analyses in spine surgery in current decade, a substantial proportion continue to show critical flaws. With increasing number of review articles in spine surgery, stringent measures must be taken to adhere to methodological quality by following PRISMA and AMSTAR guidelines to attain higher standards of evidence in published literature.


2017 ◽  
Vol 36 (3) ◽  
pp. 207-229
Author(s):  
G. Mullen

ObjectiveThe aim of this scoping review was to map evidence gathered through systematic reviews regarding adult attachment and mental health difficulties. This review highlights established, emerging, and inconsistent findings, suggesting areas for future research, and implications for theory and practice.MethodsA systematic search for meta-analyses and systematic reviews measuring adult attachment and concerning mental health difficulties was conducted. In total, 17 studies met the selection criteria.ResultsFindings were presented according to four identified themes, (1) measurement of attachment; (2) measurement of mental health difficulty; (3) intrapersonal processes related to attachment and mental health difficulties; and (4) interpersonal processes related to attachment and mental health difficulties.ConclusionsThis review highlights the connection between attachment style and mental health difficulties, and suggests that relationships can facilitate both mental health and illheath. However, the mechanisms through which insecure attachment confers risk for mental health difficulties require further research.


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