Peripheral T Cell Lymphoma Presenting as Dermatomyositis-like Eruption

2002 ◽  
Vol 6 (3) ◽  
pp. 218-220
Author(s):  
Adrienne Rencic ◽  
Susan Laman ◽  
Hossein C. Nousari
Keyword(s):  
T Cell ◽  
Unusual Case ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Peripheral T Cell Lymphoma ◽  
Cutaneous Manifestations ◽  
Cutaneous Eruption ◽  
Pathologic Features ◽  
History Of ◽  
Chest X Ray

Background: There are several conditions reported to mimic the cutaneous manifestations of dermatomyositis, including lymphoproliferative disorders. Objective: This case report presents an unusual case of peripheral T cell lymphoma mimicking dermatomyositis and discusses the clinical and pathologic features that distinguish it from dermatomyositis. Methods and Results: A 62-year-old woman presented with a two-month history of a progressive painful cutaneous eruption and interstitial infiltrates on chest x-ray. Skin biopsy revealed peripheral T cell lymphoma. The diagnosis was confirmed by lung biopsy. Conclusions: Although rare, a lymphoproliferative disorder must be included in the differential diagnosis of a cutaneous dermatomyositis-like eruption.

scholarly journals An unusual case of cytotoxic peripheral T-cell lymphoma

2015 ◽  
Vol 1 (5) ◽  
pp. 257-260 ◽  
Author(s):  
Casey Wang ◽  
Nicole Reusser ◽  
Megan Shelton ◽  
Jace Reed ◽  
Hung Doan ◽  
...  
Keyword(s):  
T Cell ◽  
Unusual Case ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Peripheral T Cell Lymphoma

scholarly journals Peripheral T-cell lymphoma, not otherwise specified: a report of 340 cases from the International Peripheral T-cell Lymphoma Project

Blood ◽  
2011 ◽  
Vol 117 (12) ◽  
pp. 3402-3408 ◽  
Author(s):  
Dennis D. Weisenburger ◽  
Kerry J. Savage ◽  
Nancy Lee Harris ◽  
Randy D. Gascoyne ◽  
Elaine S. Jaffe ◽  
...  
Keyword(s):  
Overall Survival ◽  
T Cell ◽  
Cell Lymphoma ◽  
International Prognostic Index ◽  
T Cell Lymphoma ◽  
Peripheral T Cell Lymphoma ◽  
Bulky Disease ◽  
Free Survival ◽  
Not Otherwise Specified ◽  
Pathologic Features

Abstract The International Peripheral T-cell Lymphoma Project is a collaborative effort to better understand peripheral T-cell lymphoma (PTCL). A total of 22 institutions submitted clinical and pathologic material on 1314 cases. One objective was to analyze the clinical and pathologic features of 340 cases of PTCL, not otherwise specified. The median age of the patients was 60 years, and the majority (69%) presented with advanced stage disease. Most patients (87%) presented with nodal disease, but extranodal disease was present in 62%. The 5-year overall survival was 32%, and the 5-year failure-free survival was only 20%. The majority of patients (80%) were treated with combination chemotherapy that included an anthracycline, but there was no survival advantage. The International Prognostic Index (IPI) was predictive of both overall survival and failure-free survival (P < .001). Multivariate analysis of clinical and pathologic prognostic factors, respectively, when controlling for the IPI, identified bulky disease (≥ 10 cm), thrombocytopenia (< 150 × 109/L), and a high number of transformed tumor cells (> 70%) as adverse predictors of survival, but only the latter was significant in final analysis. Thus, the IPI and a single pathologic feature could be used to stratify patients with PTCL-not otherwise specified for novel and risk-adapted therapies.

Primary Cutaneous Peripheral T-Cell Lymphoma in a Sporotrichoid Pattern: A Case Report

2017 ◽  
Vol 21 (6) ◽  
pp. 568-571
Author(s):  
Daniel J. Lewis ◽  
Harina Vin ◽  
Tiffany Hinojosa ◽  
Michael T. Tetzlaff ◽  
Bouthaina S. Dabaja ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Radiation Therapy ◽  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Cutaneous Lymphoma ◽  
Atypical Presentation ◽  
Peripheral T Cell Lymphoma ◽  
Not Otherwise Specified ◽  
History Of

We present the extraordinary case of a 72-year-old man with a history of primary cutaneous peripheral T-cell lymphoma not otherwise specified (pcPTCL-NOS) previously controlled with topical agents who developed tumours in a sporotrichoid pattern. Culture of the tumours was negative, and histopathology showed findings consistent with recurrent pcPTCL. The tumours were successfully treated with localised radiation therapy. Sporotrichoid lesions are an extremely rare and atypical presentation of cutaneous lymphoma, with only 2 other cases reported in the literature. Our case reinforces the need to include cutaneous lymphoma in the differential diagnosis of nodules on the extremities spreading in a sporotrichoid pattern. Clinical recognition of this atypical presentation of cutaneous lymphoma allows for prompt, effective treatment, which might include localised radiation therapy.

Peripheral T-Cell Lymphoma: Spectrum of Imaging Findings with Clinical and Pathologic Features

Radiographics ◽  
2003 ◽  
Vol 23 (1) ◽  
pp. 7-26 ◽  
Author(s):  
Hyun Ju Lee ◽  
Jung-Gi Im ◽  
Jin Mo Goo ◽  
Kyoung Won Kim ◽  
Byung Ihn Choi ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Imaging Findings ◽  
Peripheral T Cell Lymphoma ◽  
Pathologic Features

Classic Versus Type II Enteropathy-Associated T-Cell Lymphoma: Diagnostic Considerations

2013 ◽  
Vol 137 (9) ◽  
pp. 1227-1231 ◽  
Author(s):  
David P. Arps ◽  
Lauren B. Smith
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Routine Practice ◽  
Type Ii ◽  
Peripheral T Cell Lymphoma ◽  
Rare Type ◽  
Pathologic Features

Enteropathy-associated T-cell lymphoma is a rare type of peripheral T-cell lymphoma that characteristically involves the jejunum or ileum. Awareness of the histologic and immunophenotypic features of this subtype of lymphoma is important for accurate subclassification. Enteropathy-associated T-cell lymphoma has 2 forms, classic and type II, with different clinical and pathologic features. The 2 types will be described and discussed, with an emphasis on how to differentiate these entities in routine practice.

Sign in / Sign up

Export Citation Format

Share Document