Cytomegalovirus Scrotal Ulcer in a Renal Transplant Patient

2016 ◽  
Vol 20 (6) ◽  
pp. 567-569 ◽  
Author(s):  
Rebeca Pinca ◽  
Richard I. Crawford ◽  
Sheila Au

Background: Cytomegalovirus (CMV) is a highly prevalent herpesvirus that can present with cutaneous disease in immunocompromised individuals. This may reflect systemic involvement, which is associated with significant morbidity and mortality. Objective: To report a case of cutaneous CMV in an immunocompromised patient and to discuss the differential diagnosis of genital ulcers. Methods: A medical chart review was conducted on a patient who presented with a scrotal ulcer after renal transplantation. A review of the literature on cutaneous CMV disease was also completed. Results: Biopsy of the scrotal ulcer revealed classic findings of CMV disease. The patient also developed CMV viremia. Treatment with valganciclovir resolved his scrotal ulcer and viremia. Conclusion: The differential diagnosis for genital ulcers is broad, especially in the immunocompromised patient. Cutaneous CMV disease should be ruled out with biopsy and immunohistochemical examination in immunocompromised patients, as it may reflect systemic involvement and significantly affect patient care.

2004 ◽  
Vol 78 (2) ◽  
pp. 301-302 ◽  
Author(s):  
Milagros Ortiz ◽  
Esther Gonzalez ◽  
Miguel A. Munoz ◽  
Amado Andres

2015 ◽  
Vol 19 (1) ◽  
pp. 66-68 ◽  
Author(s):  
Alexandre Laroche ◽  
Catherine Allard ◽  
Myrna Chababi-Atallah ◽  
Mélanie Masse ◽  
Janie Bertrand

Background: Trichodysplasia spinulosa (TS) is a rare skin affection seen in immunocompromised patients, mainly those with solid organ tranplants. Objective: To report a case of a patient with classic clinical and pathologic findings for the disease so that physicians caring for this population are aware of the clinical presentation. Method: We report the case of a female patient we saw at our clinic with a diagnosis of TS. Results: The diagnosis of TS was confirmed by pathologic findings. Conclusion: TS should be considered in any immunocompromised patient with a papular facial eruption reminiscent of acne vulgaris and with keratotic spiny papules as a distinctive feature.


2003 ◽  
Vol 24 (7) ◽  
pp. 548-550 ◽  
Author(s):  
Rodrigo Morales ◽  
Michael Kirkpatrick ◽  
Barry Browne ◽  
Osemwegie Emovon

AbstractThis article describes a case of respiratory syncytial virus pneumonia believed to have been acquired nosocomially in an adult renal transplant recipient. The mode of transmission, diagnosis, and prevention of infection due to this virus in the immunocompromised patient are discussed (Infect Control Hosp Epidemiol2003;24:548-550.


2020 ◽  
pp. 014556132096893
Author(s):  
David Guirguis ◽  
Lawrence Kashat ◽  
Sara Moradi ◽  
Gregory S. Bonaiuto

Chronic nasal crusting is a commonly encountered entity in an otolaryngology office. Progressive, extensive nasal crusting with erosion is relatively unusual, however. We present the case a 58-year-old renal transplant patient with a history of vasculitis and immunosuppression who presents with subjective headache and facial pain, nasal crusting, and isolated left ethmoid sinusitis. She developed extensive intranasal necrosis and underwent multiple endoscopic sinus surgeries with intraoperative biopsies, which played a critical role in her workup and eventual diagnosis of Acanthamoeba rhinosinusitis. Although she endured a difficult course, proper diagnosis and treatment allowed for her recovery over time. The differential diagnosis for intranasal necrosis is often broad. This case highlights the wide range of etiologies to be considered in a patient with extensive nasal crusting and erosion/necrosis, and the importance of thorough diagnostic evaluation in these patients, especially those in an immunocompromised state.


Author(s):  
Daniela Alexandra Gonçalves Pereira ◽  
Eliana Patrícia Pereira Teixeira ◽  
Ana Cláudia Martins Lopes ◽  
Ricardo José Pina Sarmento ◽  
Ana Paula Calado Lopes

AbstractThe diagnosis of genital ulcers remains a challenge in clinical practice. Lipschütz ulcer is a non-sexually transmitted rare and, probably, underdiagnosed condition, characterized by the sudden onset of vulvar edema along with painful necrotic ulcerations. Despite its unknown incidence, this seems to be an uncommon entity, with sparse cases reported in the literature. We report the case of an 11-year-old girl who presented at the emergency department with vulvar ulcers. She denied any sexual intercourse. The investigation excluded sexually transmitted infections, so, knowledge of different etiologies of non-venereal ulcers became essential. The differential diagnoses are extensive and include inflammatory processes, drug reactions, trauma, and malignant tumors. Lipschütz ulcer is a diagnosis of exclusion. With the presentation of this case report, the authors aim to describe the etiology, clinical course, and outcomes of this rare disease, to allow differential diagnosis of genital ulceration.


1999 ◽  
Vol 5 (1) ◽  
pp. 67-69 ◽  
Author(s):  
Balázs Nemes ◽  
Hemangshu Podder ◽  
Jenő Járay ◽  
Gabriella Dabasi ◽  
Laura Lázár ◽  
...  

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