Clinically isolated syndromes with no further disease activity suggestive of multiple sclerosis at the age of population life expectancy
2013 ◽
Vol 20
(4)
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pp. 496-500
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Keyword(s):
The proportion of patients with clinically isolated syndrome (CIS) reported to convert to clinically definite multiple sclerosis varied between 30 and 75%. We studied the lifetime probability of remaining in the “CIS only” condition. The study was based on the longitudinally followed Gothenburg 1950–1964 incidence cohort ( n = 306). Survival analysis revealed that 17.8% of 236 attack onset patients remained “CIS only”. Patients with afferent (optic and sensory) symptoms had a better prognosis with approximately 30% of these patients remaining “CIS only”. Patients who had experienced no relapse during the first 25 years remained “CIS only” for the subsequent 25 years of follow-up.
2010 ◽
Vol 16
(5)
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pp. 576-580
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2002 ◽
Vol 8
(2)
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pp. 115-118
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2017 ◽
Vol 3
(4)
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pp. 205521731773280
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2009 ◽
Vol 11
(1)
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pp. 17-24
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2017 ◽
Vol 24
(7)
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pp. 974-981
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2015 ◽
Vol 21
(8)
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pp. 1013-1024
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2008 ◽
Vol 14
(8)
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pp. 1026-1030
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