Prognosis and Expression of Lambda Light Chains in Solitary Extramedullary Plasmacytoma of the Head and Neck: Two Case Reports and a Literature Review

Introduction. This study aimed to report the characteristics and treatment outcome of 13 patients with solitary extramedullary plasmacytomas of the head and neck and analytical literature review. Materials and Methods. Nine patients (69%) were treated with gross surgical resection followed by radiotherapy, three (23%) were primarily treated with radiotherapy alone, and one (8%) was treated with surgery alone. Results. There were 3 women and 10 men with the median age of 52 years. Nasal cavity (46%) and paranasal sinuses (23%) were the most common primary sites. After a median follow-up of 28 months, 10 patients are alive and free of disease, one is alive with multiple myeloma, and two died of multiple myeloma. In the literature review the median age was 58 years and male/female ratio was 2.7. Sinonasal tract was the most common primary site. Ten-year local control and progression to multiple myeloma rates were 88% and 23%, respectively. The 5- and the 10-year overall survival rates were 71 and 69%, respectively. Conclusion. Radiation therapy with or without surgery is an effective treatment for patients with head and neck extramedullary plasmacytoma. However, long-term follow-up for detection of local recurrence and progression to multiple myeloma is essential.

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Necrotizing soft tissue infections of the head and neck: Case reports and literature review

Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology ◽

10.1067/moe.2003.15 ◽

2003 ◽

Vol 95 (1) ◽

pp. 30-37 ◽

Cited By ~ 25

Author(s):

Jeremy McMahon ◽

Terrence Lowe ◽

David A. Koppel

Keyword(s):

Soft Tissue ◽

Literature Review ◽

Head And Neck ◽

Case Reports ◽

Soft Tissue Infections ◽

Necrotizing Soft Tissue Infections

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Case Report: Solitary Extramedullary Plasmacytoma in the Cervix Misdiagnosed as Cervical Cancer

Frontiers in Oncology ◽

10.3389/fonc.2021.685070 ◽

2021 ◽

Vol 11 ◽

Author(s):

Ji Wang ◽

Lin Jiang ◽

Xuejin Ma ◽

Tingchao Li ◽

Heng Liu ◽

...

Keyword(s):

Cervical Cancer ◽

Case Reports ◽

Extramedullary Plasmacytoma ◽

Benign Tumors ◽

Solitary Plasmacytoma ◽

Imaging Findings ◽

Mri Imaging ◽

Cervical Lesions ◽

Imaging Characteristics ◽

Solitary Extramedullary Plasmacytoma

Solitary plasmacytoma (SP) is a malignant tumor caused by the monoclonal proliferation of plasma cells, representing less than 5% of plasma cell tumors. SP can be categorized into two groups: solitary bone plasmacytoma (SBP) and solitary extramedullary plasmacytoma (SEP). SEP most commonly occurs in the head and neck and is rarely located in the reproductive system. Here, we report a case of a 77-year-old woman with SEP in the cervix who had a 7-day history of vaginal bleeding. Ultrasonography and magnetic resonance imaging (MRI) showed an oval mass in the cervix, which was initially considered as neoplastic lesions and highly suspected to be cervical cancer, but cervical leiomyoma and other benign tumors cannot be completely excluded. Subsequently, cervical biopsy showed that the tumor was SEP, and then the patient underwent surgery. The postoperative pathological diagnosis was also SEP, which confirmed the radiologist’s misjudgment. In conclusion, SEP that occurs in the cervix is remarkably rare, and only nine cases have been reported in the cervix. No case reports to date have described in detail the imaging findings of cervical SEP. This study demonstrates the MRI imaging characteristics of a patient with SEP of the cervix and reviews the imaging findings of SEP reported in the previous literature, in order to provide more extensive insights for radiologists to consider the differential diagnosis of cervical lesions.

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Clinical Features of Head and Neck Solitary Extramedullary Plasmacytoma in Taiwan

In Vivo ◽

10.21873/invivo.11769 ◽

2019 ◽

Vol 34 (1) ◽

pp. 261-265

Author(s):

CHUN-YU LAI ◽

HUA-HSIN HSIEH ◽

HOU-KUANG CHEN ◽

CHE-YI CHAO ◽

CHUN-HUNG HUA ◽

...

Keyword(s):

Head And Neck ◽

Clinical Features ◽

Extramedullary Plasmacytoma ◽

Solitary Extramedullary Plasmacytoma

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Myiasis in Patients with Head and Neck Cancer: Seldom Described but Commonly Seen

Ear Nose & Throat Journal ◽

10.1177/014556131709600704 ◽

2017 ◽

Vol 96 (7) ◽

pp. E19-E22 ◽

Cited By ~ 4

Author(s):

Fábio Muradás Girardi ◽

Maria Lúcia Scrofernecker

Keyword(s):

Head And Neck Cancer ◽

Literature Review ◽

Head And Neck ◽

Neck Cancer ◽

Case Reports ◽

Head And Neck Malignancies ◽

Underdeveloped Countries ◽

Small Series ◽

Available Information ◽

Advanced Tumors

Human myiasis is a parasitosis usually found in tropical and underdeveloped countries. It usually affects ulcerated lesions or devitalized tissues, developing after deposition of dipterous eggs. Patients with head and neck cancer are at risk to develop secondary myiasis. A representative percentage of those patients manifest with neglected and advanced tumors, usually in exposed areas and with necrotic tissues. Few case reports and small series constitute the available information about this parasitosis. Most studies have been conducted in patients with skin carcinomas, although myiasis has already been described in association with other head and neck malignancies. The authors present a series of 12 cases of myiasis secondary to head and neck cancer in addition to a literature review.

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