scholarly journals Anxiety and depression in bronchiectasis: Response to pulmonary rehabilitation and minimal clinically important difference of the Hospital Anxiety and Depression Scale

2020 ◽  
Vol 17 ◽  
pp. 147997312093329
Author(s):  
Stephanie C Wynne ◽  
Suhani Patel ◽  
Ruth E Barker ◽  
Sarah E Jones ◽  
Jessica A Walsh ◽  
...  

The aims of the study were to evaluate the responsiveness of Hospital Anxiety and Depression Scale-Anxiety (HADS-A) subscale and HADS-Depression (HADS-D) subscale to pulmonary rehabilitation (PR) in patients with bronchiectasis compared to a matched group of patients with chronic obstructive pulmonary disease (COPD) and provide estimates of the minimal clinically important difference (MCID) of HADS-A and HADS-D in bronchiectasis. Patients with bronchiectasis and at least mild anxiety or depression (HADS-A ≥ 8 or/and HADS-D ≥ 8), as well as a propensity score-matched control group of patients with COPD, underwent an 8-week outpatient PR programme (two supervised sessions per week). Within- and between-group changes were calculated in response to PR. Anchor- and distribution-based methods were used to estimate the MCID. HADS-A and HADS-D improved in response to PR in both patients with bronchiectasis and those with COPD (median (25th, 75th centile)/mean (95% confidence interval) change: HADS-A change: bronchiectasis −2 (−5, 0), COPD −2 (−4, 0); p = 0.43 and HADS-D change: bronchiectasis −2 (−2 to −1), COPD −2 (−3 to −2); p = 0.16). Using 26 estimates, the MCID for HADS-A and HADS-D was −2 points. HADS-A and HADS-D are responsive to PR in patients with bronchiectasis and symptoms of mood disorder, with an MCID estimate of −2 points.

2021 ◽  
Vol 9 (2) ◽  
pp. 19-26
Author(s):  
Yeanita ◽  
Rahmi Isma AP

ABSTRACTIntroduction: The presence of anxiety and depression in patients with Chronic Obstructive Pulmonary Disease (COPD) is often associated with greater disability, higher rates of exacerbations, increasedhospitalization and mortality. Many types of breathing exercises, such as Pursed Lips Breathing (PLB), Diaphragmatic Breathing (DBE), Respiratory Muscle Training (RMT), have been reported positivephysiological effects to reduces breathlessness, anxiety and depression in patients with COPD. This study aims to determine the effect in anxiety and depression after intervention of Inspiratory MuscleTraining (IMT) in COPD patients that received PLB.Methods: An experimental pre and post randomly study design, in August – September 2019. Control group and experimental group each performed PLB exercises while the experimental group got additionalIMT. To evaluate anxiety and depression status, Hospital Anxiety and Depression Scale (HADS) was used.Results: Twenty subjects with COPD were recruited, no significant differences of HADS score between both groups. After 6 weeks of intervention, the HADS score in each group decreased significantly, withdelta of HADS score in experimental group was greater than the control group (p<0.05).Conclusion: Improvement of HADS scores after additional IMT was better than PLB only in COPD patients.Keywords: chronic obstructive pulmonary disease; hospital anxiety and depression scale; inspiratory muscle training; pursed lips breathing.


2021 ◽  
Author(s):  
Cátia Paixão ◽  
Patrícia Rebelo ◽  
Ana Oliveira ◽  
Cristina Jácome ◽  
Joana Cruz ◽  
...  

Abstract Objective The Brief-Balance Evaluation Systems Test (Brief-BESTest) is a comprehensive, reliable, and valid balance test that provides valuable information to guide balance training in people with chronic obstructive pulmonary disease (COPD). Its clinical interpretability is, however, currently limited, as cutoff points to identify clinically relevant changes in people with COPD after pulmonary rehabilitation are still lacking. This study aimed to establish the responsiveness and minimal clinically important difference (MCID) for the Brief-BESTest in people with COPD after pulmonary rehabilitation (PR). Methods A secondary analysis of data from 2 previous studies was conducted. The modified British Medical Research Council (mMRC) dyspnea scale, the 6-Minute Walk Test (6-MWT), and the Brief-BESTest (0–24 points) were collected in people with COPD pre/post a 12-week PR program including balance training. The MCID was computed using anchor- and distribution-based methods. Changes in the 6-MWT and the mMRC were assessed and used as anchors. The pooled MCID was computed using the arithmetic weighted mean (2/3 anchor- and 1/3 distribution-based methods). Results Seventy-one people with COPD [69 years (SD = 8); 76% male; FEV1 = 49.8%predicted (SD = 18%)] were included. There was a significant improvement in the Brief-BESTest after PR [mean difference = 3 points (SD = 3)]. Significant correlations were found between the Brief-BESTest and the mMRC (r = −.31) and the 6-MWT (r = .37). The pooled MCID was 3.3 points. Conclusion An improvement of at least 3 points in the Brief-BESTest in people with COPD will enhance the interpretability of PR effects on balance performance of this population and guide tailored interventions. Impact The Brief-BESTest outcome measure is comprehensive, easily administered, and simple to interpret in clinical practice. This study represents a significant contribution toward the clinical interpretation of changes in balance in people with COPD following PR.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Christoph Nowak ◽  
Noriane A. Sievi ◽  
Christian F. Clarenbach ◽  
Esther Irene Schwarz ◽  
Christian Schlatzer ◽  
...  

Psychological morbidity is common in chronic respiratory diseases. The diagnostic accuracy of the Hospital Anxiety and Depression Scale (HADS) and risk factors for comorbid depression in chronic obstructive pulmonary disease (COPD) are addressed. Consecutive COPD patients (GOLD stage I–IV, 40–75 years old) were enrolled in a multicentre, cross-sectional cohort study. Diagnosis of depression was ascertained through clinical records. Lung function, HADS score, 6-minute walking test (6-MWT), MRC dyspnoea score, and COPD Assessment Test (CAT) were evaluated. Two hundred fifty-nine COPD patients (mean age 62.5 years; 32% female; mean FEV1 48% predicted) were included. Patients diagnosed with depression (29/259; 11.2%) had significantly higher HADS-D and HADS-Total scores than nondepressed patients (median (quartiles) HADS-D 6 [4; 9] versus 4 [2; 7], median HADS-Total 14 [10; 20] versus 8 [5; 14]). Receiver-operating characteristic plots showed moderate accuracy for HADS-D, AUC 0.662 (95%CI 0.601–0.719), and HADS-Total, AUC 0.681 (95%CI 0.620–0.737), with optimal cut-off scores of >5 and >9, respectively. Sensitivity and specificity were 62.1% and 62.6% for HADS-D compared to 75.9% and 55.2% for HADS-Total. Age, comorbidities, sex, and lower airflow limitation predicted depression. The HADS exhibits low diagnostic accuracy for depression in COPD patients. Younger men with comorbidities are at increased risk for depression.


2011 ◽  
Vol 24 (1) ◽  
pp. 128-136 ◽  
Author(s):  
Gary Cheung ◽  
Colin Patrick ◽  
Glenda Sullivan ◽  
Manisha Cooray ◽  
Catherina L. Chang

ABSTRACTBackground: Anxiety and depression are prevalent in patients with chronic obstructive pulmonary disease (COPD). This study evaluates the sensitivity and specificity of two self-administered anxiety rating scales in older people with COPD. The Geriatric Anxiety Inventory (GAI) and the Hospital Anxiety and Depression Scale (HADS) are established useful screening tools but they have not been previously validated in this population.Methods: Older people with COPD completed the GAI and the HADS along with a structured diagnostic psychiatric interview, the Mini International Neuropsychiatric Interview (MINI). The outcomes of both rating scales were compared against the diagnosis of anxiety disorders based on the MINI. Receiver operating characteristic (ROC) curves were used to identify the optimal diagnostic cut points for each scale.Results: Fourteen (25.5%) of the 55 participants, were diagnosed with an anxiety disorder. Mean GAI and HADS-anxiety subscale scores were significantly higher in subjects with an anxiety disorder than those without the diagnosis (p = 0.002 and 0.005 respectively). Both scales demonstrated moderate diagnostic value (area under the ROC curve was 0.83 for GAI and 0.79 for HADS). Optimal cut points were ≥3 (GAI) and ≥4 (HADS-anxiety subscale). At these cut-points, the GAI had a sensitivity of 85.7%, specificity of 78.0% and the HADS had a sensitivity of 78.6%, specificity 70.7%.Conclusion: Our results support the use of the GAI and HADS as screening instruments for anxiety disorders in older people with COPD. The optimal cut points in this population were lower than previously recommended for both rating scales. The results of this study should be replicated before these cut points can be recommended for general use in older people with COPD.


2020 ◽  
pp. 1-3
Author(s):  
Muhammad Alnawa

(Prevalence of anxiety and depression in patients with airway obstruction using the hospital anxiety and depression scale (HADS) in different localities of Saudi Arabia). Objective: Objective of this study is to determine the prevalence of anxiety and depression among patients with asthma and chronic obstructive pulmonary disease in different localities of Saudi Arabia. Method: This study included 420 subjects from three different places in KSA during the period between October 2015 and October 2016. All patients were instructed to answer the questionnaire of HADS. Result: The prevalence of anxiety and depression is elevated in the patients with both asthma (28%, 20%) and COPD (22%, 14%) in comparison to control group (16%, 4%) respectively. Conclusions: Anxiety and depression are more commonly encounter by the patients of asthma and COPD as compared to the normal population; this leads to bad outcomes of both diseases. Under-recognized and untreated co-morbid anxiety and depression in patients with chronic diseases have lethal consequences in the long-term. There are certain shreds of evidence that shows promising results regarding the rehabilitation of the respective disease, adopting a healthy lifestyle, and psychological and antidepressant drug therapy in reducing anxiety and depressive symptoms in patients. However, these results and findings required further elaboration to examine their efficacy in well-controlled randomized controlled trials with larger samples and long-term follow-up.


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