Anemia is Associated With Mortality Following Endovascular Repair of Abdominal Aortic Aneurysm

Aim: The aim of this study was to compare midterm mortality between anemic and nonanemic patients undergoing endovascular repair of abdominal aortic aneurysm and to assess a correlation with markers of inflammation. Methods: Anemia was defined as hemoglobin <13 (men) and <12 g/dL (women). The impact of anemia and inflammatory markers on mortality was assessed using Kaplan-Meier curves and Cox regression. Results: A total of 224 patients (12 females [5.36%]; age: 69.73 ± 8.72 years) were included; 102 (45.53%) were anemic. Median follow-up was 17 months (interquartile range: 7-25 months). Nine patients died (1.79%; 8 anemic vs 1 nonanemic). Survival was lower for patients with anemia (log-rank, P = .01). White blood cell count and C-reactive protein (CRP) differed significantly ( P < .001 and P = .01). Anemia and CRP were associated with decreased survival (Cox regression, P = .01, hazard ratio [HR]: 0.35, 95% confidence interval: 0.14-0.84 and P = .002, HR: 1.18, 95% CI: 1.06-1.31). Conclusion: Patients with anemia had decreased survival over the midterm; inflammatory markers were higher among this group.

Download Full-text

The impact of endovascular repair on specialties performing abdominal aortic aneurysm repair

Journal of Vascular Surgery ◽

10.1016/j.jvs.2015.03.042 ◽

2015 ◽

Vol 62 (3) ◽

pp. 562-568.e3 ◽

Cited By ~ 11

Author(s):

Klaas H.J. Ultee ◽

Rob Hurks ◽

Dominique B. Buck ◽

George S. DaSilva ◽

Peter A. Soden ◽

...

Keyword(s):

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Endovascular Repair ◽

Abdominal Aortic Aneurysm Repair ◽

Abdominal Aortic ◽

Aneurysm Repair ◽

The Impact ◽

Aortic Aneurysm Repair

Download Full-text

Re: ‘The Impact of Early Pelvic and Lower Limb Reperfusion and Attentive Peri-operative Management on the Incidence of Spinal Cord Ischemia During Thoraco-abdominal Aortic Aneurysm Endovascular Repair’

European Journal of Vascular and Endovascular Surgery ◽

10.1016/j.ejvs.2015.10.021 ◽

2016 ◽

Vol 51 (2) ◽

pp. 316 ◽

Cited By ~ 2

Author(s):

B. Maurel ◽

S. Haulon

Keyword(s):

Spinal Cord ◽

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Endovascular Repair ◽

Lower Limb ◽

Spinal Cord Ischemia ◽

Operative Management ◽

Abdominal Aortic ◽

The Impact

Download Full-text

Expression of MicroRNA-1281, C-Reactive Protein, and Renal Function in Individuals with Abdominal Aortic Aneurysm and their Clinical Correlation after Endovascular Repair

Brazilian Journal of Cardiovascular Surgery ◽

10.21470/1678-9741-2020-0268 ◽

2021 ◽

Vol 36 (3) ◽

Author(s):

Lais Missae ◽

Breno Rossoni ◽

Emanuel Junio Ramos Tenorio ◽

Maurício Serra Ribeiro ◽

Daniela Tirapelli ◽

...

Keyword(s):

Renal Function ◽

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Endovascular Repair ◽

Clinical Correlation ◽

C Reactive Protein ◽

Reactive Protein ◽

Abdominal Aortic

Download Full-text

Abstract 258: Significant Predictors of Survival Following Endovascular Abdominal Aortic Aneurysm Repair

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvb.35.suppl_1.258 ◽

2015 ◽

Vol 35 (suppl_1) ◽

Author(s):

Albeir Y Mousa ◽

Mike Broce ◽

Michael Yacoub ◽

Mark Bates ◽

Ali AbuRahma

Keyword(s):

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Cox Regression ◽

Abdominal Aortic Aneurysm Repair ◽

Chronic Obstructive ◽

Obstructive Pulmonary Disease ◽

Kaplan Meier ◽

Surgery Patient ◽

Abdominal Aortic ◽

One Year

Objective: To identify significant predictors of survival after abdominal aortic aneurysm (AAA) repair. Methods: A retrospective review of the prospective endovascular aortic repair (EVAR) patient registry of the “Virginia’s group” maintained by the Society for Vascular Surgery Patient Safety Organization. Patients were classified into normal (eGFR ≥60 mL/min/1.73 m 2 ), moderate chronic renal insufficiency (CRI; eGFR ≥30-59) or severe CRI (eGFR <30). Kaplan-Meier and Cox-regression were used to measure and determine the predictors of survival. Results: A total of 6410 EVAR patients were included with an age of 73.5 ± 8.4 years (majority were male 81.2%), with an average follow-up of 2.3 ± 2.0 years. Compared to patients with eGFR 30-59 and >60, those with the lowest eGFR <30 had the highest rate of post-op MI (3.8 vs. 2.2 and 0.8%;p<0.001) and stroke+MI+30-day mortality (3.8 vs. 2.4 and 0.8%; p<0.001). One year mortality was the highest in patients with the lowest eGFR (<30) (5.7 vs. 2.1 and 1.0%, respectively). Overall, 5-year survival was 80.6%. Significant predictors of decreased survival were, unstable angina (Hazard Ratio (HR), 2.5; P =0.007), age (by decade) (HR, 1.6; p<0.001, oxygen-dependent chronic obstructive pulmonary disease (HR, 3.3; P<0.001), eGFR <30 (HR, 2.4; P<0.001) and eGFR 30-59 (HR, 1.5; p<0.001), while pre-operative statin and aspirin use were associated with increased survival (HR, 0.79 and 0.78; both p=0.014, respectively). Conclusion: Reduced renal function at baseline was found to be associated with increased post operative cardiovascular events and long-term mortality following EVAR. Increased monitoring of patients with CRI seems warranted.

Download Full-text

The impact of new technologies in endovascular repair of thoraco-abdominal aortic aneurysm

Italian Journal of Vascular and Endovascular Surgery ◽

10.23736/s1824-4777.18.01387-6 ◽

2019 ◽

Vol 26 (1) ◽

Author(s):

Enrico Gallitto ◽

Rodolfo Pini ◽

Chiara Mascoli ◽

Mortalla Dieng ◽

Mohammad Abualhin ◽

...

Keyword(s):

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Endovascular Repair ◽

New Technologies ◽

Abdominal Aortic ◽

The Impact

Download Full-text

Successful Endovascular Repair of a Leaking Abdominal Aortic Aneurysm under Local Anesthesia

Swiss Surgery ◽

10.1024/1023-9332.7.2.86 ◽

2001 ◽

Vol 7 (2) ◽

pp. 86-89 ◽

Cited By ~ 17

Author(s):

Lachat ◽

Pfammatter ◽

Bernard ◽

Jaggy ◽

Vogt ◽

...

Keyword(s):

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Ct Scan ◽

Local Anesthesia ◽

Endovascular Repair ◽

Anesthetic Management ◽

High Risk Patient ◽

Invasive Technique ◽

Chronic Obstructive ◽

Abdominal Aortic

Local anesthesia is a safe and less invasive anesthetic management for the endovascular approach to elective aortic aneurysm. We have successfully extended the indication of local anesthesia to a high-risk patient with leaking aneurysm and stable hemodynamics. Patient and methods: A 86 year old patient with renal insufficiency due to longstanding hypertension, coronary artery and chronic obstructive lung disease was transferred to our hospital with a leaking abdominal aortic aneurysm. Stable hemodynamics allowed to perform a fast CT scan, that confirmed the feasibility of endovascular repair. A bifurcated endograft (24mm x 12mm x 153mm) was implanted under local anesthesia. Results: The procedure was completed within 85 minutes without problems. The complete sealing of the aneurysm was confirmed by CT scan on the third postoperative day. Twenty months later, the patient is doing well and radiological control confirmed complete exclusion of the aneurysm. Discussion: The endoluminal treatment is a minimally invasive technique. It's feasibility can be rapidly assessed by CT scan. The transfemoral implantation can be performed under local anesthesia provided that hemodynamics are stable. This anesthetic management seems to be particularly advantageous for leaking abdominal aortic aneurysm since it doesn't change the hemodynamic situation in contrast to general anesthesia. Hemodynamic instability, abdominal distension or tenderness may indicate intraperitoneal rupture and conversion to open graft repair should be performed without delay.

Download Full-text