Posterior Tibial Artery Pseudoaneurysm with Arteriovenous Fistula: Impact of Duplex Ultrasound on Diagnosis and Treatment

2017 ◽  
Vol 41 (1) ◽  
pp. 31-35
Author(s):  
Keith Himes ◽  
Amanda Bornais ◽  
Emelia Bittenbinder ◽  
Judith Cook
Keyword(s):  
Treatment Algorithm ◽  
Duplex Ultrasound ◽  
Posterior Tibial Artery ◽  
Diagnosis And Treatment ◽  
Treatment Modalities ◽  
Artery Pseudoaneurysm ◽  
Post Traumatic ◽  
Orthopedic Injuries ◽  
Venous Fistula

Post traumatic peripheral vascular injuries resulting in pseudoaneurysm (PSA) or arterial venous fistula (AVF) are rarely reported and may occur independently, or less commonly, concomitantly, following lower extremity fractures, penetrating or blunt trauma, and sports-related or orthopedic injuries. 1 Concomitant traumatic PSA and AVF requires accurate imaging and evaluation of hemodynamics for accurate diagnosis and treatment. Modalities for PSA repair include ultrasound-guided occlusion (thrombin injection), endovascular repair (coils, stents), and open surgical procedures (repair, ligation). A coexisting AVF can potentially impact the efficacy and safety of these options. This case demonstrates the important role of duplex ultrasound in the diagnosis and treatment algorithm of traumatic PSA.

Combining Chemotherapy with Immunotherapy in Colorectal Cancer: A Review

2020 ◽  
Vol 07 ◽  
Author(s):  
John Thomas Palathingal ◽  
Basil Sunny ◽  
Vismaya Vijayan
Keyword(s):  
Colorectal Cancer ◽  
Time Window ◽  
Positive Impact ◽  
Combined Treatment ◽  
Treatment Algorithm ◽  
Treatment Modalities ◽  
Cancer Society ◽  
Treatment Techniques ◽  
Comprehensive Knowledge

Abstract:: American Cancer Society estimates that about 1 in 21 men and 1 in 23 women in US will develop colorectal cancer during their lifetime. Due to the advances in screening and treatment modalities, the mortality rate has reduced. Rising resistance to treatment have directed the focus towards different approaches as combination therapies involving different treatment techniques available. One such approach is chemo-immunotherapy that targets to modulate TIME and improve the response to immunotherapy. The chemo-immunotherapy has shown a positive impact in improving the outcome of CRC treatment. The ensemble of results discussed herein supports the role of biomarkers in determining the most effective treatment algorithm. A comprehensive knowledge about the off-target effects of the cytotoxic drugs helps in designing more efficacious combined treatment. The time-window for optimal combination must also be considered carefully.

Diagnosis and treatment of chronic venous obstruction: consensus statement of the Russian experts (part 2)

2020 ◽  
pp. 22-55
Author(s):  
K.V. Lobastov ◽  
D.V. Bondarchuk ◽  
D.A. Borsuk ◽  
R.A. Bredikhin ◽  
O.V. Bukina ◽  
...  
Keyword(s):  
Consensus Statement ◽  
Relevant Literature ◽  
Clinical Manifestations ◽  
Duplex Ultrasound ◽  
Diagnosis And Treatment ◽  
Ultrasound Scan ◽  
Venous Obstruction ◽  
Venous Stenting ◽  
Chronic Venous Obstruction

This consensus statement of Russian experts is based on a review of the relevant literature on the prevalence, diagnosis, and treatment of non-thrombotic and post-thrombotic venous obstruction, as well as management of patients after venous stenting. In the Part 1 we discussed the clinical manifestations of venous obstruction, the role of duplex ultrasound scan, CT venography, MR venography, direct venography, and intravascular ultrasound scan, as well as typical findings obtained by using these methods. The authors mentioned the functional assessment of venous outflow in healthy subjects and in those with obstruction and changes in them after the intervention. In conclusion, the authors formulated the suggestions for clinical recommendations on the diagnosis of chronic venous obstruction.

Diagnosis and treatment of chronic venous obstruction: consensus statement of the Russian experts (part 1)

2020 ◽  
pp. 5-37
Author(s):  
Kirill Lobastov ◽  
Dmitry Bondarchuk ◽  
Denis Borsuk ◽  
Roman Bredikhin ◽  
Oksana Bukina ◽  
...  
Keyword(s):  
Consensus Statement ◽  
Relevant Literature ◽  
Clinical Manifestations ◽  
Duplex Ultrasound ◽  
Diagnosis And Treatment ◽  
Ultrasound Scan ◽  
Venous Obstruction ◽  
Venous Stenting ◽  
Chronic Venous Obstruction

This consensus statement of Russian experts is based on a review of the relevant literature on the prevalence, diagnosis, and treatment of non-thrombotic and post-thrombotic venous obstruction, as well as management of patients after venous stenting. In the Part 1 we discussed the clinical manifestations of venous obstruction, the role of duplex ultrasound scan, CT venography, MR venography, direct venography, and intravascular ultrasound scan, as well as typical findings obtained by using these methods. The authors mentioned the functional assessment of venous outflow in healthy subjects and in those with obstruction and changes in them after the intervention. In conclusion, the authors formulated the suggestions for clinical recommendations on the diagnosis of chronic venous obstruction.

The Role of Epigenetic Alterations Involved in Sepsis: An Overview

2018 ◽  
Vol 24 (24) ◽  
pp. 2862-2869 ◽  
Author(s):  
Fatima Ismail Hassan ◽  
Tina Didari ◽  
Fazlullah Khan ◽  
Mojtaba Mojtahedzadeh ◽  
Mohammad Abdollahi
Keyword(s):  
Disease Progression ◽  
Accurate Method ◽  
Body Fluids ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Treatment Modalities ◽  
Epigenetic Alterations

Background: Sepsis is among the leading causes of death with no specific etiology or treatment. Increase in health burden in terms of cost, morbidity, and mortality is the reason behind the continuous search for different treatment modalities which involve several targets/approach and one of them includes the involvement of epigenetics in sepsis. Objective: This review was carried out to explain the epigenetic alterations involved in sepsis, as it affects the disease progression, diagnosis, and treatment. Methods: Information used in this review was obtained from different databases including PUBMED, SCOPUS, Web of Science, and EMBASE. Keywords were used as search terms. Result: In this review, we provided a concise overview of the significant role of epigenetic alterations in sepsis pathophysiology as it relates to disease progression, diagnosis and treatment derived from in vitro, in vivo, and human studies. These mechanisms affected various targets and pathways involved in sepsis modulation, which correlates with morbidity and mortality. Change in DNA methylation pattern, histone modification, and microRNA regulation has been shown in sepsis models to silence or activate pro-inflammatory genes such as TNF-α and interleukins, anti-oxidant enzymes, and many signaling pathways. Drugs that target these pathways have proven effective in sepsis treatment. Conclusion: Epigenetic processes involve specific enzymes detected in the blood and other body fluids which can potentially serve as diagnostic, therapeutic, as well as prognostic tools in sepsis. Epigenetic mechanisms can provide a highly sensitive and accurate method for sepsis diagnosis using blood and other body fluids.

1763: Stage Migration of upper Tract Transitional Cell Carcinoma: An Argument for the Continued Role of Endourologic Diagnosis and Treatment

2004 ◽  
Vol 171 (4S) ◽  
pp. 466-466
Author(s):  
Stephen A. Boorjian ◽  
Casey K. Ng ◽  
Ravi Munver ◽  
R. Ernest Sosa ◽  
E. Darracott Vaughan ◽  
...  
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Diagnosis And Treatment ◽  
Stage Migration ◽  
Upper Tract
Sign in / Sign up

Export Citation Format

Share Document