scholarly journals Efficacy of Selective Transarterial Chemotherapy Using a Port System for Angiosarcomas of the Face and Scalp

2008 ◽  
Vol 14 (2) ◽  
pp. 137-141
Author(s):  
K. Iwamoto ◽  
S. Suzuki ◽  
A. Kurata ◽  
K. Sato ◽  
J. Niki ◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Physiological Saline ◽  
Proximal Part ◽  
Poor Clinical Outcome ◽  
Infusion Chemotherapy ◽  
The Face ◽  
Port System ◽  
Useful Life ◽  
Transarterial Infusion ◽  
Standard Agent

Angiosarcoma is a rare, highly malignant tumor with a poor clinical outcome. From January 2004 to September 2005, we advocated transarterial chemotherapy using a port system for four patients with angiosarcomas of the face and scalp. A heparin coated ANTHRON P-U catheter was introduced into the feeding artery. The proximal part of the P-U catheter was connected to the port system and buried in subcutaneous tissue. The amount of chemotherapeutic drug applied using the port system was almost the same as the conventional intravenous dose. Paclitaxel was the standard agent, at 50–100mg/diluted in 15–30 ml of physiological saline fluid slowly injected over 0.5–1 hour. For immunotherapy where appropriate, r-IL2 was mainly used at a dose of 70.000U/diluted in 5ml of physiological saline fluid injected into the port system over 30 seconds. This was continued for two to three weeks (five days/week) until recognition of a disappearance of the tumor. Macroscopic size reduction of the tumor was achieved in three out of the four cases. One case could not be evaluated because of eruptions induced by immunotherapy. Unfortunately two patients died after placement of port system, but the other two are still alive and are enjoying useful lives. Transarterial infusion chemotherapy using such a port system may be particularly effective for angiosarcoma in the early stages because small lesions with limited invasion mean a small territory of blood supply to be covered, and useful life was possible because the port system embedded in subcutaneous tissue allows treatment in an out-patient clinic.

Noma and Necrotizing Fasciitis of the Face and Neck

2021 ◽  
Author(s):  
Lauren E. Miller ◽  
David A. Shaye
Keyword(s):  
Soft Tissue ◽  
Necrotizing Fasciitis ◽  
Head And Neck ◽  
Subcutaneous Tissue ◽  
Neck Region ◽  
Superficial Fascia ◽  
Soft Tissue Infections ◽  
Head And Neck Region ◽  
Necrotizing Soft Tissue Infections ◽  
The Face

AbstractNecrotizing fasciitis (NF) is part of the class of necrotizing soft tissue infections characterized by rapid fascial spread and necrosis of the skin, subcutaneous tissue, and superficial fascia. If left untreated, NF can rapidly deteriorate into multiorgan shock and systemic failure. NF most commonly infects the trunk and lower extremities, although it can sometimes present in the head and neck region. This review provides an overview of NF as it relates specifically to the head and neck region, including its associated clinical features and options for treatment. Noma, a related but relatively unknown disease, is then described along with its relationship with severe poverty.

Lack of antilipolytic effect of lactate in subcutaneous abdominal adipose tissue during exercise

1999 ◽  
Vol 86 (6) ◽  
pp. 1800-1804 ◽  
Author(s):  
François Trudeau ◽  
Sylvain Bernier ◽  
Isabelle de Glisezinski ◽  
François Crampes ◽  
François Dulac ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Tissue ◽  
Maximal Oxygen Consumption ◽  
Physiological Saline ◽  
Tissue Blood Flow ◽  
Glycerol Concentration ◽  
Abdominal Adipose Tissue ◽  
Glycerol Level ◽  
Good Physical Condition ◽  
Subcutaneous Abdominal Adipose Tissue

The purpose of our study was to evaluate the potential inhibition of adipose tissue mobilization by lactate. Eight male subjects (age, 26.25 ± 1.75 yr) in good physical condition (maximal oxygen uptake, 59.87 ± 2.77 ml ⋅ kg−1 ⋅ min−1; %body fat, 10.15 ± 0.89%) participated in this study. For each subject, two microdialysis probes were inserted into abdominal subcutaneous tissue. Lactate (16 mM) was perfused via one of the probes while physiological saline only was perfused via the other, both at a flow rate of 2.5 μl/min. In both probes, ethanol was also perfused for adipose tissue blood flow estimation. Dialysates were collected every 10 min during rest (30 min), exercise at 50% maximal oxygen consumption (120 min), and recovery (30 min) for the measurement of glycerol concentration. During exercise, glycerol increased significantly in both probes. However, no differences in glycerol level and ethanol extraction were observed between the lactate and control probes. These findings suggest that lactate does not impair subcutaneous abdominal adipose tissue mobilization during exercise.

Management of Enteroatmospheric Fistulae in the Open Abdomen

2010 ◽  
Vol 76 (6) ◽  
pp. 637-639 ◽  
Author(s):  
Philip T. Ramsay ◽  
Vicente A. Mejia
Keyword(s):  
Open Abdomen ◽  
Subcutaneous Tissue ◽  
Case Series ◽  
Early Mobilization ◽  
Morbidity And Mortality ◽  
Surgical Patients ◽  
General Surgeon ◽  
Enteroatmospheric Fistula ◽  
The Face ◽  
Tissue Flaps

There are few complications dreaded more by the general surgeon than the development of an enteroatmospheric fistula in the face of the open abdomen. The open abdomen has become a valuable tool in the treatment of trauma and complex surgical patients. The development of enteroatmospheric fistulae leads to increased cost, morbidity, and mortality. In our case series, we describe the use of Malecot catheters and early mobilization of skin and subcutaneous tissue flaps to manage enteroatmospheric fistulae. All of our patients were discharged from the hospital and did not develop any complications from the procedure. All of our patients’ fistulae ultimately closed. This procedure could lead to decreased cost and morbidity.

scholarly journals Masson’s tumor of the pineal region: case report

2018 ◽  
Vol 128 (6) ◽  
pp. 1725-1730 ◽  
Author(s):  
Lefko T. Charalambous ◽  
Anirudh Penumaka ◽  
Jordan M. Komisarow ◽  
Amanda C. Hemmerich ◽  
Thomas J. Cummings ◽  
...  
Keyword(s):  
Nervous System ◽  
Case Report ◽  
Vascular Malformations ◽  
Subcutaneous Tissue ◽  
Pineal Region ◽  
Vascular Tumors ◽  
Intravascular Papillary Endothelial Hyperplasia ◽  
Masson’S Tumor ◽  
The Face ◽  
Papillary Endothelial Hyperplasia

Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson’s tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and can easily be mistaken clinically, radiologically, and histologically for angiosarcoma, organizing hematoma, or other vascular malformations. IPEH accounts for roughly 2% of all vascular tumors and is extremely rare intracranially, with only 23 reported cases compared with more than 300 cases of IPEH occurring in the skin and subcutaneous tissue. To date, it has never been reported to occur in the pineal region. The authors report the case of a patient with an IPEH in the pineal region who underwent complex resection and experienced reversal of neurological symptoms.

scholarly journals PARRY ROMBERG SYNDROME

2016 ◽  
Vol 25 (4) ◽  
pp. 209-211
Author(s):  
Alexis-Virgil Cochino ◽  
◽  
Sigrid Covaci ◽  
Oana-Maria Farkas ◽  
◽  
...  
Keyword(s):  
Nervous System ◽  
Borrelia Burgdorferi ◽  
Subcutaneous Tissue ◽  
Rare Condition ◽  
Localized Scleroderma ◽  
Hemifacial Atrophy ◽  
The Face ◽  
Parry Romberg Syndrome ◽  
Facial Hemiatrophy

Parry-Romberg syndrome, which is also known as progressive facial hemiatrophy, is a variant of localized scleroderma. This is a rare condition (OMIM # 141300), characterized by a progressive but self-limited atrophy of the skin and subcutaneous tissue on one side of the face. We present the case of a 9 year old boy with a typical presentation of hemifacial atrophy, with Borrelia burgdorferi infection without any changes of the nervous system.

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