Synthesis of 1,2,3-triazole-substituted 6,7-dihydroindolizin-8(5H)-one derivatives mediated by Selectfluor

2019 ◽  
Vol 43 (5-6) ◽  
pp. 179-183
Author(s):  
Yulin Huang ◽  
Jiaying Lei ◽  
Xinliang Fu ◽  
Wenlin Xie ◽  
Xiaofang Li
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Crystallographic Analysis ◽  
X Ray ◽  
High Resolution Mass ◽  
Moderate Yield ◽  
Resolution Mass

The 1,2,3-triazole and 1 H-1,2,3-benzotriazole-substituted 6,7-dihydroindolizin-8(5 H)-one derivatives were synthesized by the reaction of ( E)-7-(arylmethylidene)-6,7-dihydroindolizin-8(5 H)-ones with 1,2,3-triazole and 1 H-1,2,3-benzotriazole in the presence of Selectfluor in moderate yield. The structures of all the products were characterized thoroughly by nuclear magnetic resonance, infrared, and high-resolution mass spectrometry together with X-ray crystallographic analysis.

scholarly journals Synthesis of spiro[benzo[4,5]imidazo[2,1-b][1,3]thiazole-2,3-thiolane]s via sulfa-Michael/aldol cascade reactions

2019 ◽  
Vol 43 (1-2) ◽  
pp. 63-66 ◽  
Author(s):  
Jiaying Lei ◽  
Xinliang Fu ◽  
Yulin Huang ◽  
Xiaofang Li
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Cascade Reactions ◽  
Cascade Reaction ◽  
Crystallographic Analysis ◽  
X Ray ◽  
Resolution Mass

The sulfa-Michael/aldol cascade reaction of ( Z)-2-arylmethylidene-benzo[4,5]imidazo[2,1- b]thiazol-3(2H)-ones and 1,4-dithiane-2,5-diol afforded novel 2-aryl-4-hydroxy-spiro[benzo[4,5]imidazo[2,1- b][1,3]thiazole-2,3-thiolan]-3-ones in moderate yields. The structures of all the products were characterized thoroughly by nuclear magnetic resonance, infrared and high-resolution mass spectrometry together with X-ray crystallographic analysis.

scholarly journals Neo-Aplysiatoxin A Isolated from Okinawan Cyanobacterium Moorea Producens

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 457 ◽  
Author(s):  
Mioko Kawaguchi ◽  
Masayuki Satake ◽  
Bo-Tao Zhang ◽  
Yue-Yun Xiao ◽  
Masayuki Fukuoka ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Growth Inhibition ◽  
Spectroscopic Data ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
Resolution Mass ◽  
Nuclear Magnetic

A new aplysiatoxin derivative, neo-aplysiatoxin A (1), along with seven known compounds, neo-debromoaplysiatoxin A (2), dolastatin 3 (3), lyngbic acid (4), malyngamide M (5), hermitamide A (6), (−)-loliolide (7), and (+)-epiloliolide (8), was isolated from the Okinawan cyanobacterium Moorea producens. Their structures were elucidated on the basis of spectroscopic data, including high-resolution mass spectrometry and nuclear magnetic resonance. The compounds were evaluated for cytotoxic and diatom growth inhibition activities.

Fluorescence staining of salicylaldehyde azine, and applications in the determination of potassium tert-butoxide

RSC Advances ◽  
2016 ◽  
Vol 6 (36) ◽  
pp. 30636-30641 ◽  
Author(s):  
Jinlai Yang ◽  
Jian Rui ◽  
Xu Xu ◽  
Yiqin Yang ◽  
Jun Su ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Fluorescence Staining ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
Resolution Mass

Salicylaldehyde azine (1), with an aggregation-induced emission (AIE) function, was synthesized from salicylaldehyde and characterized by nuclear magnetic resonance, high resolution mass spectrometry, and X-ray single crystal diffraction.

The metabolic pathway of flonicamid in oranges using an orthogonal approach based on high-resolution mass spectrometry and nuclear magnetic resonance

2017 ◽  
Vol 9 (11) ◽  
pp. 1718-1726 ◽  
Author(s):  
R. López-Ruiz ◽  
A. B. Ruiz-Muelle ◽  
R. Romero-González ◽  
I. Fernández ◽  
J. L. Martínez Vidal ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Metabolic Pathway ◽  
Metabolic Profiling ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
Resolution Mass ◽  
Nuclear Magnetic

An orthogonal approach has been used to perform a metabolic profiling study of flonicamid in orange fruits.

scholarly journals Synthesis of 2-(1-Oxo-2,3-Dihydro-1H-Pyrrolizin-2-yl)-2-(Aryl)Acetonitrile Derivatives Via Michael Addition of Trimethylsilyl Cyanide

2018 ◽  
Vol 42 (9) ◽  
pp. 467-470 ◽  
Author(s):  
Demin Ren ◽  
Jiaying Lei ◽  
Xianyong Yu ◽  
Yulin Huang ◽  
Xiaofang Li
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Michael Addition ◽  
High Resolution Mass Spectrometry ◽  
Crystallographic Analysis ◽  
X Ray ◽  
Trimethylsilyl Cyanide ◽  
Tetrabutylammonium Fluoride ◽  
High Resolution Mass ◽  
Resolution Mass

Several 2-aryl-2-(1-oxo-2,3-dihydro-1 H-pyrrolizin-2-yl)acetonitrile derivatives were synthesised by Michael addition of ( E)-2-arylidene-2,3-dihydro-1 H-pyrrolizin-1-ones with trimethylsilyl cyanide in the presence of tetrabutylammonium fluoride in moderate yields. The structures of all of the products were fully characterised by NMR, IR and high-resolution mass spectrometry, together with X-ray crystallographic analysis.

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