Synthesis of 2-(1-Oxo-2,3-Dihydro-1H-Pyrrolizin-2-yl)-2-(Aryl)Acetonitrile Derivatives Via Michael Addition of Trimethylsilyl Cyanide
2018 ◽
Vol 42
(9)
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pp. 467-470
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Keyword(s):
X Ray
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Several 2-aryl-2-(1-oxo-2,3-dihydro-1 H-pyrrolizin-2-yl)acetonitrile derivatives were synthesised by Michael addition of ( E)-2-arylidene-2,3-dihydro-1 H-pyrrolizin-1-ones with trimethylsilyl cyanide in the presence of tetrabutylammonium fluoride in moderate yields. The structures of all of the products were fully characterised by NMR, IR and high-resolution mass spectrometry, together with X-ray crystallographic analysis.
2019 ◽
Vol 43
(1-2)
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pp. 63-66
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2020 ◽
Vol 308
◽
pp. 110180
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2020 ◽
2020 ◽
Vol 86
(8)
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pp. 23-31
2015 ◽
Vol 33
(10)
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pp. 1046
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