scholarly journals The Development of a Glucose Dehydrogenase 3D-Printed Glucose Sensor: A Proof-of-Concept Study

2017 ◽  
Vol 12 (1) ◽  
pp. 176-182 ◽  
Author(s):  
Anngela Adams ◽  
Aldin Malkoc ◽  
Jeffrey T. La Belle
Keyword(s):  
Glucose Sensor ◽  
Glucose Dehydrogenase ◽  
Proof Of Concept ◽  
Concept Study ◽  
3D Printed

scholarly journals Computationally Designed 3D Printed Self-Expandable Polymer Stents with Biodegradation Capacity for Minimally Invasive Heart Valve Implantation: A Proof-of-Concept Study

2017 ◽  
Vol 4 (1) ◽  
pp. 19-29 ◽  
Author(s):  
María Sol Cabrera ◽  
Bart Sanders ◽  
Olga J.G.M. Goor ◽  
Anita Driessen-Mol ◽  
Cees W.J Oomens ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Heart Valve ◽  
Proof Of Concept ◽  
Concept Study ◽  
3D Printed ◽  
Valve Implantation

scholarly journals Medication eluting devices for the field of OBGYN (MEDOBGYN): 3D printed biodegradable hormone eluting constructs, a proof of concept study

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0182929 ◽  
Author(s):  
Karthik Tappa ◽  
Udayabhanu Jammalamadaka ◽  
David H. Ballard ◽  
Todd Bruno ◽  
Marissa R. Israel ◽  
...  
Keyword(s):  
Proof Of Concept ◽  
Concept Study ◽  
3D Printed

scholarly journals Preparations of Rectal Suppositories Containing Artesunate

Pharmaceutics ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 222 ◽  
Author(s):  
Suzanne Persaud ◽  
Sandra Eid ◽  
Natalia Swiderski ◽  
Ioannis Serris ◽  
Hyunah Cho
Keyword(s):  
Polyethylene Glycol ◽  
Severe Malaria ◽  
Short Proof ◽  
Physical Parameters ◽  
Proof Of Concept ◽  
Concept Study ◽  
Advantages And Disadvantages ◽  
3D Printed ◽  
Rectal Suppositories ◽  
Rectal Artesunate

Rectal artesunate suppositories are a useful option for pre-referral treatment of severe malaria, specifically in children under 6 years of age in remote malaria-endemic areas. The main challenges are to improve the solubility of drugs in the rectal fluids and prevent the product from turning rancid or melting in a tropical climate. In this short proof-of-concept study, three types of rectal suppositories of artesunate were prepared: (i) polyethylene glycol (PEG)-based suppositories carrying free artesunate (non-modified artesunate), (ii) PEG-based suppositories carrying artesunate-loaded micelles and (iii) 3D-printed suppositories carrying a PEG/artesunate mixture. Physical parameters of suppositories, release profiles of artesunate (the fastest to the slowest: ii≥i>iii) and thermostability (the most stable to the least stable: iii>ii>i) of suppositories at increased temperature were assessed to determine the advantages and disadvantages of each formulation.

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