Characteristic Dynamic Enhancement Pattern of MR Imaging for Malignant Thyroid Tumor

2011 ◽  
Vol 24 (3) ◽  
pp. 392-394
Author(s):  
H. Hwang ◽  
Y.N. Park ◽  
Y.S. Shim ◽  
S.S. Byun ◽  
H.S. Kim
2019 ◽  
Vol 119 ◽  
pp. 108633 ◽  
Author(s):  
Roberto Cannella ◽  
Giuseppe Brancatelli ◽  
Balasubramanya Rangaswamy ◽  
Marta I. Minervini ◽  
Amir A. Borhani ◽  
...  

2016 ◽  
Vol 9 ◽  
pp. CPath.S31734 ◽  
Author(s):  
Magda H. A. Nasreldin ◽  
Eman A. Ibrahim ◽  
Somaia A. Saad El-Din

Branchial pouch-derived anomalies may arise from remnants of the first, second, or third/fourth branchial arches. Branchial pouch-related structures are found within the thyroid gland in the form of solid cell rests, epithelial lined cyst with or without an associated lymphoid component, thymic and/or parathyroid tissue, and less commonly in the form of heterotopic cartilage. We present a rare case of left solid thyroid swelling nearby two cervical nodules in a seven-year-old female with a clinical diagnosis suggestive of malignant thyroid tumor with metastasis to the cervical lymph nodes. Histopathological examination revealed that it was compatible with third/fourth branchial pouch-derived anomaly composed of mature cartilage and thymic and parathyroid tissues for clinical and radiological correlations.


2012 ◽  
Vol 81 (10) ◽  
pp. 2457-2462 ◽  
Author(s):  
Rajan T. Gupta ◽  
Daniele Marin ◽  
Daniel T. Boll ◽  
Daniela B. Husarik ◽  
Drew E. Davis ◽  
...  

2007 ◽  
Vol 26 (6) ◽  
pp. 1548-1555 ◽  
Author(s):  
Indra C. van den Bos ◽  
Shahid M. Hussain ◽  
Roy S. Dwarkasing ◽  
Wim C.J. Hop ◽  
Pieter E. Zondervan ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2585
Author(s):  
Aurora Mirabile ◽  
Matteo Biafora ◽  
Leone Giordano ◽  
Gianluigi Arrigoni ◽  
Maria Giulia Cangi ◽  
...  

Anaplastic thyroid carcinoma (ATC) is a very rare, highly aggressive malignant thyroid tumor with an overall survival from 3 to 5 months in most of the cases. Even the modern and intensive treatments seem not to be enough to provide a cure, also for the resectable ones, and the role of chemotherapy is still unclear but does not seem to prolong survival. Nevertheless, some patients survive longer and have a better outcome, even in the presence of metastasis, than what the literature reports. We present the case of a 64-year-old female affected by ATC, treated on February 2018 with surgery followed by chemoradiation. One year after surgery, the patient developed a subcutaneous recurrence that was radically resected and is still alive 29 months after the diagnosis. We propose a systematic review of the literature to deepen the knowledge of the prognostic factors of ATC with the aim to recognize and select the patients with a better outcome, even if metastatic, and to describe a very uncommon site of metastatization.


Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 919
Author(s):  
Koichiro Kimura ◽  
Junichi Tsuchiya ◽  
Yoshio Kitazume ◽  
Mitsuhiro Kishino ◽  
Keiichi Akahoshi ◽  
...  

Paired box 6 (PAX6) is a transcription factor that plays a critical role in tumor suppression, implying that the downregulation of PAX6 promotes tumor growth and invasiveness. This study aimed to examine dynamic computed tomography (CT) features for predicting pancreatic neuroendocrine neoplasms (Pan-NENs) with low PAX6 expression. We retrospectively evaluated 51 patients with Pan-NENs without synchronous liver metastasis to assess the pathological expression of PAX6. Two radiologists analyzed preoperative dynamic CT images to determine morphological features and enhancement patterns. We compared the CT findings between low and high PAX6 expression groups. Pathological analysis identified 11 and 40 patients with low and high PAX6 expression, respectively. Iso- or hypoenhancement types in the arterial and portal phases were significantly associated with low PAX6 expression (p = 0.009; p = 0.001, respectively). Low PAX6 Pan-NENs showed a lower portal enhancement ratio than high PAX6 Pan-NENs (p = 0.044). The combination based on enhancement types (iso- or hypoenhancement during arterial and portal phases) and portal enhancement ratio (≤1.22) had 54.5% sensitivity, 92.5% specificity, and 84.3% accuracy in identifying low PAX6 Pan-NENs. Dynamic CT features, including iso- or hypoenhancement types in the arterial and portal phases and lower portal enhancement ratio may help predict Pan-NENs with low PAX6 expression.


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