scholarly journals Pulvinar sign in a case of anti-HU paraneoplastic encephalitis

2016 ◽  
Vol 29 (6) ◽  
pp. 436-439 ◽  
Author(s):  
Pierre-Luc Gamache ◽  
Maude-Marie Gagnon ◽  
Martin Savard ◽  
François Émond

This article reports the case of a 68-year-old patient with anti-HU antibodies paraneoplastic encephalitis. The clinical manifestations were atypical and the paraclinical work-up, notably the magnetic resonance imaging (MRI) showing bilateral posterior thalamic hyperintensities (pulvinar sign), misleadingly pointed towards a variant Creutzfeld–Jakob disease. After presenting the case, the differential diagnosis of the pulvinar sign is discussed along with other important diagnostic considerations.

2019 ◽  
Vol 22 (3) ◽  
pp. 425-431
Author(s):  
Neiandro Santos Galvão ◽  
Antonione Santos Bezerra Pinto ◽  
Alan Leandro Carvalho Farias ◽  
André Luiz Ferreira Costa ◽  
Sérgio Lúcio Pereira de Castro Lopes ◽  
...  

Ameloblastoma is an odontogenic tumor that shares clinical and imaging characteristics with other lesions of the jaws, such as odontogenic keratocyst, which makes the diagnosis difficult. However, in addition to radiographic and tomographic examinations, Magnetic Resonance Imaging (MRI) has been increasingly used, contributing with relevant additional information about the differentiation between solid and liquid components of the lesion. This case report was conducted to present two variations of ameloblastoma and discuss the radiographic, tomographic and MRI contribution in the differential diagnosis between ameloblastoma and odontogenic keratocyst.The signal intensity in T1-weighted MRI revealed internal fluid content in both cases, which was important in the differential diagnosis with other intraosseous lesions such as odontogenic keratocysts. This is probably due to the presence of keratin that increases the viscosity of the content and also for an intermediate signal intensity signal in T2-weighted MRI. Therefore, MRI revealed important internal characteristics of the reported lesions, which was very useful in the establishment of the differential diagnosis with other lesions.


2017 ◽  
Vol 21 (04) ◽  
pp. 403-414
Author(s):  
William Palmer ◽  
Miriam Bredella ◽  
Arvin Kheterpal

AbstractMusculotendinous disorders of the abdomen and pelvis are common causes of pain in both athletes and nonathletes. Magnetic resonance imaging (MRI) is the modality of choice in the work-up of these patients. This article focuses on the MRI appearance of normal anatomy and spectrum of musculotendinous disorders in the abdomen and pelvis including muscle strains and tears, avulsions and apophysitis, muscular contusions, athletic groin pain, and gluteal aponeurotic/proximal iliotibial band injuries. Normal biomechanics and injury mechanisms are discussed.


2001 ◽  
Vol 115 (1) ◽  
pp. 48-49 ◽  
Author(s):  
P. Martinez Devesa ◽  
M. J. Wareing ◽  
D. A. Moffat

A case is presented of an entirely intracanalicular meningioma in a 48-year-old woman that was excised via a conventional translabyrinthine approach to the internal auditory canal (IAC). Pre-operative magnetic resonance imaging (MRI) suggested that the tumour was a vestibular schwannoma (VS). Histological examination confirmed the intra-operative impression that the tumour was a meningioma. Although VS is by far the commonest intracanalicular tumour, the differential diagnosis includes meningioma. MRI is unable to distinguish between these two entities when the tumour is located entirely in the internal auditory canal.


2017 ◽  
Vol 24 (4) ◽  
pp. 459-471 ◽  
Author(s):  
Maria A Rocca ◽  
Paola Valsasina ◽  
Victoria M Leavitt ◽  
Mariaemma Rodegher ◽  
Marta Radaelli ◽  
...  

Objective: To investigate resting state (RS) functional connectivity (FC) abnormalities within the principal brain networks in a large cohort of multiple sclerosis (MS) patients, to define the trajectory of FC changes over disease stages and their relation with clinical and structural magnetic resonance imaging (MRI) measures. Methods: RS functional magnetic resonance imaging (fMRI), clinical, and neuropsychological evaluation were obtained from 215 MS patients and 98 healthy controls. Connectivity abnormalities and correlations with clinical/neuropsychological/imaging measures were evaluated. We analyzed seed-voxel FC with seven major hubs, producing one visual/sensory, one motor, two cognitive, one cerebellar, and two subcortical networks. Results: MS patients showed reduced network average RS FC versus controls in the default-mode network. At regional level, a complex pattern of decreased and increased RS FC was found. Reduced RS FC mainly involved sensorimotor, cognitive, thalamic, and cerebellar networks, whereas increased RS FC involved visual/sensory and subcortical networks. Reduced RS FC correlated with T2 lesions. Reduced thalamic RS FC correlated with better neuropsychological performance, whereas for all remaining networks reduced FC correlated with more severe clinical/cognitive impairment. Conclusion: Increased and decreased RS FC occurs in MS and contributes to a wide spectrum of clinical manifestations. RS FC reduction is related to T2 lesions. Such a paradigm is inverted for the thalamic network.


2005 ◽  
Vol 119 (2) ◽  
pp. 140-143 ◽  
Author(s):  
A S Shaw ◽  
S E J Connor

Epidermoid tumours are non-neoplastic inclusion cysts representing up to 1.1 per cent of all intracranial tumours, typically presenting with symptoms related to pressure or intracranial rupture in the fourth or fifth decade of life. The authors present a case of a parasellar epidermoid cyst which has ruptured in to the nasopharynx; to the best of their knowledge, this has not been previously reported. The computed tomography (CT) and magnetic resonance imaging (MRI) are presented. The pathology and radiological features of epidermoid tumours are discussed, particularly in relation to extracranial connections. The differential diagnosis of lesions eroding the central skull base is reviewed.


1996 ◽  
Vol 9 (4) ◽  
pp. 209-213
Author(s):  
John C. Adair ◽  
Ronald L. Schwartz ◽  
Thomas A. Eskin ◽  
Anthony T. Yachnis ◽  
Kenneth M. Heilman

We evaluated a 66-year-old man with a rapidly progressive, akinetic-rigid dementia syndrome. Despite extensive testing, which included magnetic resonance imaging (MRI), we were unable to make the correct antemortem diagnosis. Autopsy demonstrated spontaneous progressive multifocal leukoencephalopathy. This report illustrates that even in the absence of characteristic MRI findings, this uncommon cause of dementia should be considered in the differential diagnosis of rapidly progressive, akinetic-rigid syndromes with dementia.


2021 ◽  
pp. 140-147
Author(s):  
D. S. Klyachko ◽  
Yu. A. Bystrova ◽  
S. A. Bystrov ◽  
S. V. Ryazantsev ◽  
V. V. Partyushko ◽  
...  

Introduction. The relevance of the study is due to the complexity of the differential diagnosis of Kosten's syndrome and meningioma in the area of the cerebellar bridge angle of the brain, as well as the severe suffering of patientsThe purpose of our study: development of an algorithm for the approach to the differential diagnosis of meningioma of the cerebellar angle and Kosten's syndrome.Materials and methods. To accomplish the set tasks, we examined 22 patients who complained of headache, hearing impairment, sensation of tinnitus, pain and crepitus in the temporomandibular joint during movements of the lower jaw, paresthesia of the oral and nasal mucosa. All patients were assigned studies: cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI) of the TMJ according to indications.Results. Since complaints can lead patients to see doctors of various specialties, it is necessary to be able to differentiate between Costen's syndrome and a tumor of the cerebral pons-cerebral angle. In Costen's syndrome, the pain most often has an aching character, in contrast to the volumetric formations of the brain, in which the pain is burning, spreading along the branches of the facial or trigeminal nerve. One of the main methods of excluding a brain tumor is magnetic resonance imaging.Conclusions. The most significant modern method for diagnosing Costen's syndrome and meningioma of the cerebellopontine angle is magnetic resonance imaging (MRI) of the TMJ and the brain. Differential signs of Costen's syndrome are distal displacement of the head of the lower jaw, diagnosed by CBCT and MRI, as well as displacement of the articular disc (determined by MRI). A meningioma of the cerebellopontine angle is indicated by the burning nature of pain in half of the face, as well as confirmation of the diagnosis by magnetic resonance imaging of the brain.


2015 ◽  
Vol 9 (4) ◽  
pp. 424-427
Author(s):  
Alan Peres Valente ◽  
Paula da Cunha Pinho ◽  
Leandro Tavares Lucato

ABSTRACT Creutzfeldt-Jacob disease (CJD) is a rare condition caused by a pathogenic prion protein that evolves with rapidly progressive dementia and death. The clinical presentation may sometimes be misleading. Magnetic Resonance Imaging (MRI) aids diagnosis with patterns that can guide or confirm clinical hypotheses. Two cases of rapidly progressive dementia with ataxia, myoclonus and restricted diffusion on MRI in cortical/basal ganglia are presented to draw attention to CJD.


2018 ◽  
Vol 90 (12) ◽  
pp. 101-106
Author(s):  
O V Stukalova ◽  
N V Meladze ◽  
D A Ivanova ◽  
T M Shvecz ◽  
S A Gaman ◽  
...  

Heart sarcoidosis diagnosis presents great difficulties due to the absence of specific clinical manifestations. Most often, the diagnosis is established during autopsy. Magnetic resonance imaging (MRI) of the heart with contrast enhancement is one of the most informative methods of intravital diagnosis of cardiac sarcoidosis. In this article, two clinical cases, shows the role of MRI of the heart with contrast enhancement in the diagnosis of cardiac sarcoidosis.


2021 ◽  
Vol 12 ◽  
Author(s):  
Ryuichi Koizumi ◽  
Naohisa Ueda ◽  
Atsushi Mugita ◽  
Katsuo Kimura ◽  
Hitaru Kishida ◽  
...  

The diagnosis of presymptomatic Creutzfeldt–Jakob disease (CJD) is challenging. The levels of total tau protein, 14-3-3 protein, and protease-resistant isoform of prion protein (PrPres) in the cerebrospinal fluid; periodic sharp wave complexes on electroencephalography; and diffusion-weighted imaging (DWI) of brain magnetic resonance imaging (MRI) have all been used to diagnose symptomatic CJD, but none of these markers have been established in the diagnosis of presymptomatic CJD. Here, we report a case of genetic CJD with the V180I mutation in which a small punctate cortical hyperintensity was detected on DWI 6 months before symptom onset and 9 months before diagnosis. Presymptomatic CJD is currently impossible to diagnose because of the lack of established early diagnostic markers. However, since MRI is increasingly used in daily clinical practice, the chance detection of such DWI abnormalities would have important implications in terms of providing a clue to examine a highly specific early diagnostic marker to be developed in the future for CJD. This will allow presymptomatic intervention by disease-modifying therapy in the near future.


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