scholarly journals Erythromycin, QTc interval prolongation, and torsade de pointes: Case reports, major risk factors and illness severity

2014 ◽  
Vol 2 (2) ◽  
pp. 47-59 ◽  
Author(s):  
Jules C. Hancox ◽  
Mehrul Hasnain ◽  
W. Victor R. Vieweg ◽  
Michael Gysel ◽  
Michelle Methot ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Reports ◽  
Torsade De Pointes ◽  
Illness Severity ◽  
Qtc Interval ◽  
Interval Prolongation ◽  
Qtc Interval Prolongation

scholarly journals Changes In QTc Interval Duration Among Heroin Addicts On Methadone Treatment

2015 ◽  
Vol 16 (3) ◽  
pp. 217-228
Author(s):  
Mirjana Jovanovic ◽  
Mladen Divnic ◽  
Milan Jovanovic ◽  
Sasa Babic ◽  
Katarina Nikic Djuricic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Illicit Drugs ◽  
Methadone Treatment ◽  
Torsade De Pointes ◽  
Diagnostic Methods ◽  
Qtc Interval ◽  
Interval Prolongation ◽  
Safety Level ◽  
Co Morbidity ◽  
Qtc Interval Prolongation

AbstractThis paper aimed to collect and unite facts known about the effect of methadone treatment on QTc interval prolongation that could determine precipitating factors in the development of heart arrhythmias and their consequences (Torsade de Pointes and sudden cardiac death), and to raise the methadone treatment safety level.Studies conducted up to now clearly demonstrate that methadone therapy evokes changes in the heart’s electrical conduction, but those studies also show that QTc interval prolongation could be precipitated by other factors. The most often present risk factors in our research were dose of methadone, co-medication, and co-morbidity, but other relevant risk factors were gender, age, misuse of illicit drugs, therapy length and tobacco use.Active participation in modern treatment processes and implementation of knowledge acquired recently into daily practice, such as setting up reutilized questionnaires and diagnostic methods to expose higher risk for complications and providing broader therapeutic range for cases of drug replacement necessity, will enhance therapy safety level and bring us to the next step of resocialization of these patients, which needs to remain the final goal of treatment.

Risperidone, QTc interval prolongation, and torsade de pointes: a systematic review of case reports

2013 ◽  
Vol 228 (4) ◽  
pp. 515-524 ◽  
Author(s):  
W. Victor R. Vieweg ◽  
Mehrul Hasnain ◽  
Jules C. Hancox ◽  
Adrian Baranchuk ◽  
Geneviève C. Digby ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Torsade De Pointes ◽  
Qtc Interval ◽  
Interval Prolongation ◽  
Qtc Interval Prolongation

scholarly journals Quetiapine, QTc interval prolongation, and torsade de pointes: a review of case reports

2013 ◽  
Vol 4 (3) ◽  
pp. 130-138 ◽  
Author(s):  
Mehrul Hasnain ◽  
W. Victor R. Vieweg ◽  
Robert H. Howland ◽  
Christopher Kogut ◽  
Ericka L. Breden Crouse ◽  
...  
Keyword(s):  
Case Reports ◽  
Torsade De Pointes ◽  
Qtc Interval ◽  
Interval Prolongation ◽  
Qtc Interval Prolongation

scholarly journals Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem

2013 ◽  
Vol 3 (4) ◽  
pp. 219-232 ◽  
Author(s):  
W. Victor R. Vieweg ◽  
Mehrul Hasnain ◽  
Robert H. Howland ◽  
Thomas Clausen ◽  
Jayanthi N. Koneru ◽  
...  
Keyword(s):  
Case Reports ◽  
Torsade De Pointes ◽  
Qtc Interval ◽  
Interval Prolongation ◽  
Qtc Interval Prolongation

Meperidine-induced QTc-interval prolongation: prevalence, risk factors, and correlation to plasma drug and metabolite concentrations

2017 ◽  
Vol 55 (03) ◽  
pp. 275-285 ◽  
Author(s):  
Guillermo Alberto Keller ◽  
María Cedilia Villa Etchegoyen ◽  
Nicolás Fernández ◽  
Nancy Mónica Olivera ◽  
Patricia Noemi Quiroga ◽  
...  
Keyword(s):  
Risk Factors ◽  
Qtc Interval ◽  
Plasma Drug ◽  
Interval Prolongation ◽  
Qtc Interval Prolongation ◽  
Metabolite Concentrations

scholarly journals QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0199028 ◽  
Author(s):  
Flávia Medeiros Fernandes ◽  
Eliane Pereira Silva ◽  
Rand Randall Martins ◽  
Antonio Gouveia Oliveira
Keyword(s):  
Risk Factors ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Qtc Interval ◽  
Interval Prolongation ◽  
Qtc Interval Prolongation
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