scholarly journals Prevalence of Helicobacter pylori infection in sexual partners of H. pylori‐ infected subjects: Role of gastroesophageal reflux

2018 ◽  
Vol 6 (10) ◽  
pp. 1470-1476 ◽  
Author(s):  
Dolores Sgambato ◽  
Giulio Visciola ◽  
Emanuele Ferrante ◽  
Agnese Miranda ◽  
Lorenzo Romano ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastroesophageal Reflux ◽  
Sexual Partners ◽  
Helicobacter Pylori Infection ◽  
H Pylori

scholarly journals Helicobacter pylori infection reduces the risk of gastroesophageal reflux disease

2021 ◽  
pp. 96-101
Author(s):  
R. I. Khlynova ◽  
O. M. Khromtsova ◽  
R. B. Berdnikov ◽  
I. B. Khlynov
Keyword(s):  
Helicobacter Pylori ◽  
Gastroesophageal Reflux Disease ◽  
Gastric Mucosa ◽  
Gastroesophageal Reflux ◽  
Observational Study ◽  
Reflux Disease ◽  
Helicobacter Pylori Infection ◽  
Cross Sectional ◽  
Biopsy Specimens ◽  
H Pylori

The aim is to study the effect of Helicobacter pylori infection on risk of developing gastroesophageal reflux disease. Materials and methods - cross-sectional observational study of 1007 patients with dyspepsia syndrome who underwent videoesophagogastroduodenoscopy with biopsy and histological examination of biopsy specimens of the gastric mucosa by OLGA-system. The age, gender, overweight, cigarette smoking, presence of Helicobacter pylori infection and gastritis stage were assessed. Results - the study showed a significant decrease in the incidence of gastroesophageal reflux disease in patients with positive H. Pylori status by 4% (RR 0,68; 95% CI, 0.49-0.94, p=0,041). The risk of developing gastroesophageal reflux disease significantly higher in overweight (RR 2,62; 95% CI 2,0-3,56; р<0,001) men (RR 1,76; 95% CI 1,33-2,32; р=0,0046) who smoked cigarettes (RR 3,23; 95% CI 2,45-4,24; р<0,001) and was not associated with the patient’s age and the stage of gastritis (р>0,05). Conclusion - a significant reduction in the frequency and risk of developing gastroesophageal reflux disease in patients with Helicobacter pylori infection is demonstrated.

scholarly journals ASSOCIATION OF DUODENAL EOSINOPHILIC INFILTRATE WITH HELICOBACTER PYLORI INFECTION, BUT NOT WITH FUNCTIONAL DYSPEPSIA

2020 ◽  
Vol 57 (1) ◽  
pp. 74-78 ◽  
Author(s):  
Carine LEITE ◽  
Luiz Edmundo MAZZOLENI ◽  
Diego de Mendonça UCHOA ◽  
Juliana Araújo CASTANHO ◽  
Felipe MAZZOLENI ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Functional Dyspepsia ◽  
Eosinophil Count ◽  
Gastrointestinal Symptoms ◽  
Duodenal Mucosa ◽  
Helicobacter Pylori Infection ◽  
Eosinophilic Infiltrate ◽  
Urease Test ◽  
H Pylori

ABSTRACT BACKGROUND: The role of Helicobacter pylori infection on eosinophilic infiltration in duodenal mucosa is poorly studied. An increase in the number of eosinophils in duodenum has been associated with functional dyspepsia. OBJECTIVE: To evaluate the influence of H. pylori infection on duodenal eosinophil count and the role of eosinophilic infiltrate of duodenum in functional dyspepsia. METHODS: Positive and negative H. pylori individuals were included. Both functional dyspeptic patients according to Rome III criteria (cases) and individuals without gastrointestinal symptoms (controls) were enrolled. They were submitted to upper endoscopy and H. pylori infection was verified by gastric histopathology and urease test. Eosinophils in the duodenal mucosa were counted in five high-power fields, randomly selected on slides of endoscopic biopsies. RESULTS: Thirty-nine H. pylori positive (mean age 40.5 and 69.2% women) and 24 negative patients (mean age 37.3 and 75% women) were included. The influence of the infection was observed in the duodenal eosinophil count, which was higher in infected individuals: median 13.2 vs 8.1 in non-infected individuals (P=0.005). When we analyzed patients according to symptoms, cases - mean age 39.6; 71.4% women - and controls - mean age 38.7; 71.4% women - had similar duodenal eosinophil count: median 11.9 and 12.6 respectively (P=0.19). CONCLUSIONS: We did not demonstrate association of duodenal eosinophil count with functional dyspepsia but found association with H. pylori infection.

P.04.6 PREVALENCE OF H. PYLORI INFECTION IN SEXUAL PARTNERS OF H. PYLORI INFECTED SUBJECTS: ROLE OF GASTROESOPHAGEAL REFLUX

2016 ◽  
Vol 48 ◽  
pp. e145
Author(s):  
D. Sgambato ◽  
G. Visciola ◽  
C. Tuccillo ◽  
A. Miranda ◽  
A. Federico ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Sexual Partners ◽  
H Pylori

scholarly journals Demographics and Clinical and Endoscopic Characteristics of Patients with Helicobacter pylori Infection and Gastroesophageal Reflux Disease: A Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Amir Mari ◽  
Naim Mahroum ◽  
Nicola Luigi Bragazzi ◽  
Mahran Shalaata ◽  
Tawfik Khoury ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Regression Analysis ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Multivariate Regression ◽  
Multivariate Regression Analysis ◽  
Urease Test ◽  
H Pylori

Background. The correlation between Helicobacter pylori (H. pylori) and gastroesophageal reflux disease (GERD) is complex. Some studies showed a protective role of H. pylori infection against GERD. This study was aimed at assessing the role of H. pylori infection in GERD utilizing a large cohort of patients diagnosed with GERD. Methods and Materials. All patients who underwent gastroscopy for an indication of GERD during the study period between 2015 and 2017 at the EMMS Nazareth Hospital were considered eligible for the study and therefore were included. H. pylori infection was determined by the rapid urease test or histology. Severity of esophagitis was assessed using the Los Angeles classification. Univariate analysis was performed to figure out differences between patients according to H. pylori infection status. Multivariate regression analysis was conducted to illustrate the predictors of positivity for H. pylori infection. Results. 2,508 GERD patients were included with a median age of 49.42±17.96 years. H. pylori infection was detected in 299 (11.9%) patients. GERD patients with H. pylori infection were found to be younger (48.83±17.42 years versus 44.57±17.69 years, p<0.001), have the tendency to smoke more (1406 (63.6%) versus 266 (89.0%), p<0.001), and use more proton pump inhibitors or PPIs (1314 (59.5%) versus 242 (80.9%), p<0.001). In multivariate regression analysis, age (OR 0.987, p<0.001), smoking status (OR 0.190, p<0.001), use of ASA/NSAIDs (OR 1.652, p=0.004), and use of statins (OR 0.499 (95%CI 0.295-0.846), p=0.010) were found significant among H. pylori-positive individuals. H. pylori-positive subjects have less severe esophagitis and more hiatus hernia. Conclusion. Patients with GERD and H. pylori infection were significantly younger, tended to smoke more, and used more PPIs and had significantly lower grades of esophagitis compared to noninfected ones.

scholarly journals The Association Between Helicobacter Pylori Infection and Erosive Gastroesophageal Reflux Disease; a Cross-Sectional Study

2021 ◽  
Author(s):  
Ramin Niknam ◽  
Kamran Bagheri Lankarani ◽  
Mohsen Moghadami ◽  
Seyed Alireza Taghavi ◽  
Leila Zahiri ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Hiatus Hernia ◽  
Reflux Disease ◽  
Cross Sectional Study ◽  
Helicobacter Pylori Infection ◽  
Sectional Study ◽  
Cross Sectional ◽  
H Pylori

Abstract Background The association between H. pylori (Helicobacter pylori) infection and gastroesophageal reflux disease (GERD) is a complex and confusing subject, so we designed this study. Method In a cross-sectional study, all patients referred for endoscopy due to dyspepsia were enrolled. The diagnosis of erosive GERD was made by endoscopy. Patients with normal esophagus were selected as comparison group. Random gastric biopsies were taken from all participants to diagnose H. pylori infection. Result In total, 1916 patients were included in this study, of whom 45.6% had GERD. The mean age (SD) was 42.95 (16.32). Overall, 1442 (75.3%) patients were positive for H. pylori infection. The frequency of H. pylori infection in mild GERD patients was higher than the severe GERD, but this difference was not significant (P=0.214). Except for sociodemographic status (P < 0.001), other variables including gender, age, ethnicity, body mass index (BMI), smoking, and presence of hiatus hernia in patients had no significant association with the frequency of H. pylori infection. According to Robust Poisson regression models analysis, the association of H. pylori (PR 1.026;95%CI 0.990-1.064; P=0.158) and sociodemographic status were not significantly different between the two groups. But smoking, increased BMI, older age, presence of hiatus hernia, and peptic ulcer diseases were significantly associated with GERD compared with the non-GERD group. Conclusion In our results, there was no association between H. pylori infection and erosive GERD. Further studies are recommended, especially considering the effects of pathophysiological and other confounding factors on H. pylori and GERD.

scholarly journals Role of Helicobacter pylori in the genesis of gastric ulcerations among smokers and nonsmokers

1997 ◽  
Vol 3 (2) ◽  
pp. 316-321
Author(s):  
M., A. El Barrawy ◽  
M. I. Morad ◽  
M. Gaber
Keyword(s):  
Helicobacter Pylori ◽  
Significant Risk ◽  
Helicobacter Pylori Infection ◽  
Gastric Ulcers ◽  
Cigarette Smokers ◽  
Male Patients ◽  
H Pylori

Helicobacter pylori infection was investigated by three different methods [serologically, microbiologically and biochemically] in 210 male patients aged 20-40 years. Gastric ulcers were diagnosed in 126 patients in which H. pylori infection showed a significant association X [2] = 162.8]. Smokers had a higher rate of infection than nonsmokers, both among patients with gastric ulcers [99% compared to 79%] and without. The risk of H. pylori infection was computed for different categories of smoker. Heavy cigarette smokers were found to have the highest risk, followed by moderate to mild cigarette smokers and communal shisha smokers;neither private shisha nor cigar/pipe smokers showed any significant risk

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