scholarly journals Coexistence of systemic lupus erythematosus and multiple sclerosis. A case report and literature review

2018 ◽  
Vol 4 (2) ◽  
pp. 205521731876833 ◽  
Author(s):  
Elisa Carolina Jácome Sánchez ◽  
María Ariana García Castillo ◽  
Victor Paredes González ◽  
Fernando Guillén López ◽  
Edgar Patricio Correa Díaz
Keyword(s):  
Multiple Sclerosis ◽  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Lupus Erythematosus ◽  
Case Reports ◽  
Systemic Lupus Erythematous ◽  
Systemic Lupus ◽  
Diagnostic Challenge ◽  
The World ◽  
Low Prevalence

Multiple sclerosis (MS) and systemic lupus erythematous (SLE) are autoimmune diseases, the coexistence of which is uncommon in patients. Owing to the rarity of this condition, the distinction between MS and SLE is a diagnostic challenge for neurologists. We present a case report in which MS and SLE were present in the same patient. There are few case reports in the world on the association between MS and SLE. The following case report is the first of its kind in which both MS and SLE are present in a patient from a country with low prevalence of MS such as Ecuador.

scholarly journals Recurrent ascites in systemic lupus erythematosus treated with rituximab - a case report and review of pseudo-pseudo Meigs’ syndrome

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Sarah Compton ◽  
Sarah Luebker ◽  
DeAnna Baker Frost
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Pleural Effusion ◽  
Large Volume ◽  
Lupus Erythematosus ◽  
Case Reports ◽  
Ca 125 ◽  
Initial Symptom ◽  
Systemic Lupus ◽  
First Case

Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disease with multisystem consequences. Pseudo-pseudo Meigs’ syndrome (PPMS), or Tjalma syndrome, is a newly recognized manifestation of SLE that is characterized by increased CA-125 level, pleural effusion, and ascites without evidence of tumor. PPMS is relatively rare and likely under-recognized. To our knowledge, there are 11 published case reports about PPMS. In nearly half of the PPMS cases, ascites is the initial symptom of SLE. The pathophysiology of this syndrome is not completely understood but thought to be in part due to chronic inflammation, which is supported by symptoms abating with immunosuppression. We report a case of a 20-year-old woman with known SLE who developed recurrent large volume ascites, subsequently leading to the diagnosis of PPMS, requiring rituximab for additional immunosuppression. To our knowledge, this is the first case of using rituximab as a successful treatment for PPMS.

scholarly journals Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – Masquerade Diagnosis: A Case Report

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Mohd Sharil Iman Mohd Hanafi ◽  
Mohammad Che’ Man ◽  
Shahidah Che Alhadi
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Lupus Erythematosus ◽  
Social Life ◽  
Medical Condition ◽  
Classification Criteria ◽  
Psychiatric Ward ◽  
Systemic Lupus ◽  
Diagnostic Challenge ◽  
Disease Case

Introduction: Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course, broad spectrum of clinical presentation that mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease. Case report: We highlighted a case of a man, lived with diagnosis of Schizophrenia for almost 15 years subsequently revealed him suffered from neuropsychiatric lupus as he fulfilled the SLE classification criteria. His initial presentation was altered sensorium treated as acute psychosis-the tip of an iceberg to the underlying disease. His multiple admissions to psychiatric ward were believed contributed by episode of lupus flare. Necessary investigation is important to exclude another medical condition before make a diagnosis of Schizophrenia using DSM-V criteria. The misdiagnosis has significantly impaired his social life and untreated disease had leads to morbidity and severe organ damage. This case emphasizes on the crucial aspect of assessing patient as a whole, follow-up the progression and re-evaluates patient’s condition for a new hint. Even though there is no cure yet for SLE, correct and early diagnosis is able to guide for individualized treatment and thus helping in good disease control that warrant better outcome.

scholarly journals Systemic Lupus Erythematosus Simulating Kikuchi Fujimoto’s Disease: A Case Report

2015 ◽  
Vol 32 (4) ◽  
pp. 231-234
Author(s):  
Mohammad Rafiqul Islam ◽  
Abul Hayat Manik ◽  
Jannat Jeeba ◽  
Mohammod Omar Kasru ◽  
Rakib Hasan Mohammed ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lymph Node ◽  
Lupus Erythematosus ◽  
Case Reports ◽  
Sporadic Case ◽  
Lymph Node Biopsy ◽  
Systemic Lupus ◽  
Rare Association ◽  
Node Biopsy ◽  
The World

Kikuchi Fujimoto’s disease (KFD) is a rare, immunemediated, self-limiting disorder with unique histopathological features. KFD is usually seen in young Asian females; however, cases have been reported throughout the world and in all ethnicities. It has been recognized that there is a rare association between Systemic Lupus Erythematosus (SLE) and KFD via sporadic case reports. The exact pathophysiological relationship between these two diseases is still unclear. We report a case of a young Asian female who presented with persistent fever followed by development of lymphadenopathy and was diagnosed as Kikuchi Fujimoto’s disease based on lymph node biopsy. Although an SLE workup was done and she initially did not meet the American Rheumatology Association (ARA) diagnostic criteria for lupus.The lymph node biopsy did not show typical features of SLE. At last criteria of SLE became obvious with time and case was diagnosed as SLE.J Bangladesh Coll Phys Surg 2014; 32: 231-234

scholarly journals Metabolomics in Autoimmune Diseases: Focus on Rheumatoid Arthritis, Systemic Lupus Erythematous, and Multiple Sclerosis

Metabolites ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 812
Author(s):  
Naeun Yoon ◽  
Ah-Kyung Jang ◽  
Yerim Seo ◽  
Byung Hwa Jung
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Systemic Lupus Erythematosus ◽  
Drug Discovery ◽  
Autoimmune Diseases ◽  
Lupus Erythematosus ◽  
Drug Response ◽  
Systemic Lupus Erythematous ◽  
Systemic Lupus ◽  
Metabolic Mechanism

The metabolomics approach represents the last downstream phenotype and is widely used in clinical studies and drug discovery. In this paper, we outline recent advances in the metabolomics research of autoimmune diseases (ADs) such as rheumatoid arthritis (RA), multiple sclerosis (MuS), and systemic lupus erythematosus (SLE). The newly discovered biomarkers and the metabolic mechanism studies for these ADs are described here. In addition, studies elucidating the metabolic mechanisms underlying these ADs are presented. Metabolomics has the potential to contribute to pharmacotherapy personalization; thus, we summarize the biomarker studies performed to predict the personalization of medicine and drug response.

Endocrine malignancies and systemic lupus erythematosus: case report

2019 ◽  
Author(s):  
Nadia Ghariani Fetoui ◽  
Rima Gammoudi ◽  
Najet Ghariani ◽  
Yosra Hasni ◽  
Racha Fekih ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Systemic Lupus Erythematosus Case
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