scholarly journals Hepatocellular carcinoma with disseminated skeletal muscle metastasis

2017 ◽  
Vol 6 (7) ◽  
pp. 205846011771670
Author(s):  
Ezamin Abdul Rahim ◽  
Mohamad SF Noh ◽  
Nur A Ngah ◽  
Mohamad S Suraini ◽  
Mubarak M Yusof
Keyword(s):  
Hepatocellular Carcinoma ◽  
Skeletal Muscle ◽  
Poor Prognosis ◽  
Skeletal Muscles ◽  
Rare Case ◽  
Case Reports ◽  
Extrahepatic Metastasis ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis ◽  
To Come

Hepatocellular carcinoma (HCC) is the commonest primary tumor of the liver and carries a poor prognosis when diagnosed late or left untreated. Treatment relies heavily on the stage of the tumor when diagnosed. Extrahepatic metastasis is known to occur; these are mainly reported via autopsy studies or isolated case reports. Knowledge of extrahepatic metastasis is crucial in order to avoid unnecessary surgery. We report a rare case of a patient at our center, diagnosed to have HCC, who underwent treatment successfully, only to come back with extrahepatic metastasis to the skeletal muscles.

scholarly journals Carcinoma Lung Presenting with Skeletal Muscle Metastasis: Case Report with Review of Literature

2021 ◽  
Vol 07 (02) ◽  
pp. e121-e123
Author(s):  
Ankit Lalchandani ◽  
Yogeshwar Shukla ◽  
Mohammad Masoom Parwez
Keyword(s):  
Skeletal Muscle ◽  
Poor Prognosis ◽  
Treatment Initiation ◽  
Clinical Approach ◽  
Review Of Literature ◽  
Diagnostic Challenge ◽  
Lung Cancers ◽  
Delay In Diagnosis ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

AbstractLung cancers usually present very late with distant metastasis, thereby carrying a poor prognosis. Metastasis at unusual sites such as extremity musculature does create a diagnostic challenge. This leads to delay in diagnosis and treatment initiation and further worsens the prognosis of the patient. Not many cases have been reported as of now and no standard guidelines are available regarding clinical approach in such cases. We have presented one of such cases to emphasize on importance of early detection and differentiation of such lesions from primary soft tissue malignancies.

scholarly journals Gluteal muscle metastasis with peritoneal dissemination from gastric cancer during postoperative adjuvant chemotherapy: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Shotaro Korehisa ◽  
Akira Kabashima ◽  
Michihiro Ichimanda ◽  
Kenji Umeda ◽  
Hidenori Koso ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Skeletal Muscle ◽  
Adjuvant Chemotherapy ◽  
Poor Prognosis ◽  
Peritoneal Dissemination ◽  
Gluteal Muscle ◽  
Postoperative Adjuvant Chemotherapy ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis ◽  
Signet Cell

Abstract Background Skeletal muscle metastasis from gastric cancer is rare and has a poor prognosis. We reported a case of gluteal muscle metastasis with peritoneal dissemination from gastric cancer during postoperative adjuvant chemotherapy. Case presentation A 64-year-old man with gastric cancer underwent distal gastrectomy with D2 lymph node resection. The pathological diagnosis was poorly differentiated adenocarcinoma and signet cell carcinoma, T3N3bM0, Stage IIIC. Metastases were found in all regional lymph nodes, except 11p. The resection margin was negative. S-1 plus docetaxel therapy was administered as postoperative adjuvant chemotherapy. Six month post-operation, the patient presented with right gluteal muscle tenderness and abdominal distension. Computed tomography revealed a solid mass in the right gluteal muscle, a disseminated nodule on the abdominal wall, and massive ascites. Pathological examination of the gluteal muscle revealed signet cell carcinoma, similar to the resected gastric cancer. The tumor was diagnosed as gastric cancer metastases. Ascites cytology was class V. Thereafter, the patient underwent one course of capecitabine plus cisplatin combined with trastuzumab. Radiation therapy was also administered to relieve the pain of gluteal muscle metastasis. However, chemoradiotherapy was ineffective, and the patient died 2 months after the recurrence. Conclusions Skeletal muscle metastasis and peritoneal dissemination during adjuvant chemotherapy indicated a poor prognosis.

scholarly journals A Case of Hepatocellular Carcinoma with Recurrence of Skeletal Muscle Metastasis to the Right Lower Leg 9 Years after Hepatectomy

2021 ◽  
Vol 54 (1) ◽  
pp. 16-24
Author(s):  
Hiromasa Namba ◽  
Toshiya Kamiyama ◽  
Shingo Shimada ◽  
Tatsuya Orimo ◽  
Akihisa Nagatsu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Skeletal Muscle ◽  
Lower Leg ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis ◽  
The Right

Skeletal Muscle Metastasis from a Cecal Mucinous Adenocarcinoma: A Case Report

2008 ◽  
Vol 59 (5) ◽  
pp. 329
Author(s):  
Dong Hyun Lee ◽  
Young Hwan Lee ◽  
Kyung Jae Jung ◽  
Young Chan Park ◽  
Ho Kyun Kim ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Case Report ◽  
Mucinous Adenocarcinoma ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

Skeletal Muscle Metastasis from Colorectal Cancer: Report of a Case

2008 ◽  
Vol 24 (6) ◽  
pp. 492 ◽  
Author(s):  
Pyong Wha Choi ◽  
Chul Nam Kim ◽  
Han Seong Kim ◽  
Jung Min Lee ◽  
Tae Gil Heo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Skeletal Muscle ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

Skeletal Muscle Metastasis Secondary to Cancer - A Report of Seven Cases

2005 ◽  
Vol 110 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Yoichi Koike ◽  
Masahito Hatori ◽  
Schoichi Kokubrun
Keyword(s):  
Skeletal Muscle ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

scholarly journals Solitary Skeletal Muscle Metastasis as First Site of Recurrence of Cervical Cancer: A Case Report

2017 ◽  
Vol 10 (2) ◽  
pp. 694-698 ◽  
Author(s):  
Indumathy Varadarajan ◽  
Aparna Basu ◽  
Sherri Besmer ◽  
Jaganmohan Poli ◽  
Scott Richard ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cervical Cancer ◽  
Case Report ◽  
African American Woman ◽  
American Woman ◽  
Extensive Literature ◽  
Upper Arm ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

Cervical cancer is the fourth most common cancer in women worldwide, with a large majority of prevalence (85%) in developing countries. As of 2012, it accounts for 7.5% of all female cancer deaths. Despite its high prevalence, skeletal muscle metastasis from cervical cancer is extremely uncommon. In our extensive literature search, we were able to find only 8 cases where skeletal muscle metastasis was the only site of recurrence. We report a case of a 52-year-old African-American woman with a past medical history of cervical cancer (stage IIIB) who presented with pain and swelling in her left upper arm over the preceding 2 months. MRI of the left upper arm showed a solid well-circumscribed mass measuring 7.0 × 2.8 × 2.5 cm, deep to the biceps. Biopsy of the mass revealed a metastatic squamous cell carcinoma that was p16-positive. PET scan showed that the lesion was the sole site of metastasis. She received local radiation with concurrent chemotherapy. Follow-up MRI 6 months after the completion of therapy showed resolution of the mass. She has remained disease-free for the last 24 months as evidenced by a PET/CT scan in May 2016. In this case report, we discuss the role of imaging and pathology in the diagnosis of a solitary metastatic lesion. This case also emphasizes the importance of a close follow-up which aids in early intervention, increasing overall survival.

scholarly journals Skeletal Muscle Metastasis of a GIST: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Olga D. Savvidou ◽  
George D. Chloros ◽  
Georgios D. Agrogiannis ◽  
Penelope Korkolopoulou ◽  
Georgios N. Panagopoulos ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Case Report ◽  
Soft Tissue ◽  
Gastrointestinal Stromal Tumors ◽  
Review Of The Literature ◽  
Soft Tissue Metastasis ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal tumors of the gastrointestinal tract. The most common sites of metastasis are the liver and the peritoneum, whereas metastasis to soft tissue is rare. The authors present the case of a 78-year-old male with a soft tissue metastasis of a GIST and the current literature is reviewed.

scholarly journals Challenge of treating cancer amid the COVID-19 pandemic: case of skeletal muscle metastasis from primary carcinoma of the lung mistaken as sarcoma

2020 ◽  
Author(s):  
Maria Gloria Elisha Casas ◽  
Mamer Rosario ◽  
Geoffrey Battad ◽  
Adrienne Camille Mercado ◽  
Trisha Ann Hermogenes ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Skeletal Muscle ◽  
Radial Nerve ◽  
Frozen Section ◽  
Tumor Resection ◽  
Primary Lung Cancer ◽  
Histopathological Analysis ◽  
Intraoperative Frozen Section ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

Abstract Background. The authors report on an extremely rare case of skeletal muscle metastasis from primary lung cancer that involved the radial nerve and humerus, which was “overtreated” with wide tumor resection and frozen autograft reconstruction upon misdiagnosis of sarcoma by intraoperative frozen section, amid pressure of expediting hospital care during the COVID-19 pandemic. Case presentation. A 61-year-old male living outside Metro Manila presented with painful mass in his left distal arm during the enhanced community quarantine, and requested admission upon testing negative for COVID-19. Imaging studies suggested a diagnosis of soft tissue sarcoma involving the radial nerve and humerus, and intending to prevent nosocomial SARS-CoV-2 infection of patient, treatment was expedited by foregoing biopsy and opting for intraoperative frozen section prior to resection. Frozen section findings suggested malignancy intraoperatively, and we proceeded with wide tumor resection and frozen autograft reconstruction of the humerus using plates and screws. However, permanent sections revealed metastatic carcinoma from primary non-small cell lung cancer, with PET scan confirming lung mass in the right apical lobe. Conclusion. The report concludes that establishment of a definite tumor diagnosis by final histopathological analysis is indispensable, even when planning for emergent surgery in the time of COVID-19 pandemic.

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