scholarly journals Primary Rosai-Dorfman Disease in 39-Year-Old Woman With Osseous Tibial Lesion Manifestion: A Case Report and Literature Review

2021 ◽  
Vol 6 (4) ◽  
pp. 247301142110600
Author(s):  
Jasmin Mansoori ◽  
Olivia Fisher ◽  
Ivana O. Akinyeye ◽  
Michael A. Sobolevsky ◽  
Robert H. Quinn
Keyword(s):  
Case Report ◽  
Osteolytic Lesion ◽  
Magnetic Resonance Images ◽  
Unknown Etiology ◽  
Medial Malleolus ◽  
Ankle Pain ◽  
Plain Radiographs ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Physical Mass

Rosai-Dorfman disease (RDD), otherwise known as sinus histiocytosis with massive lymphadenopathy (SHML), is a very rare and typically benign disorder of unknown etiology with <10% bone involvement. The report is of a case seen at the authors’ hospital of a patient presenting with several months’ onset unspecified nontraumatic ankle pain. There was no physical mass or lymphadenopathy appreciated on examination. Plain radiographs and magnetic resonance images demonstrated an osteolytic lesion at the medial malleolus. Biopsy revealed the diagnosis of intraosseous manifestation of Rosai-Dorfman disease.

scholarly journals HISTOCYTOPATHOLOGICAL DIAGNOSIS OF ROSAI-DORFMAN DISEASE: CASE REPORT AND LITERATURE REVIEW

2021 ◽  
Author(s):  
Zephania Abraham ◽  
Zerd Francis ◽  
Advera Ngaiza ◽  
Aveline Kahinga ◽  
Faustine Bukanu
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Sinus Histiocytosis ◽  
Unknown Etiology ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Disease Case

Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease) being a rare benign proliferative self-limiting disease of the cells of macrophage-histiocyte family is of unknown etiology and presents with massive lymphadenopathy. We are hereby reporting a case of RDD presenting with massive bilateral cervical and submandibular lymphadenopathy, diagnosed by histocytopathology.

scholarly journals A unique combination of Rosai-Dorfman disease and mycosis fungoides: a case report

2018 ◽  
Vol 6 ◽  
pp. 2050313X1877219 ◽  
Author(s):  
Amanda J Shelley ◽  
Nordau Kanigsberg
Keyword(s):  
Case Report ◽  
T Cell ◽  
Mycosis Fungoides ◽  
Cell Lymphoma ◽  
Cervical Lymphadenopathy ◽  
B Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Unknown Etiology ◽  
Unique Combination ◽  
Rosai Dorfman Disease

Rosai-Dorfman disease (RDD) is a rare histiocytic condition of unknown etiology. Patients with RDD classically present with massive painless cervical lymphadenopathy. However, extra-nodal disease occurs in approximately 40% of cases, with the skin being among the most commonly involved sites. Patients with isolated extra-nodal involvement may present without adenopathy. Reports of RDD occurring in patients with Hodgkin’s lymphoma, and B-cell lymphoma have been published, but there has only been one previous report of RDD in a patient with a T-cell lymphoma. This case report documents a unique combination of RDD and mycosis fungoides (MF), a cutaneous T cell lymphoma. This report also highlights diagnostic challenges in RDD due to the rarity of the condition and its variable presentation.

scholarly journals Cytodiagnosis of Rosai–Dorfman disease masquerading as lymphoma: A case report with brief review of literature

2018 ◽  
Vol 10 (04) ◽  
pp. 460-463
Author(s):  
Manjari Kishore ◽  
Prajwala Gupta ◽  
Arvind Ahuja ◽  
Minakshi Bhardwaj
Keyword(s):  
Case Report ◽  
Sinus Histiocytosis ◽  
Male Child ◽  
Differential Diagnoses ◽  
Review Of Literature ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Cytological Features

ABSTRACTRosai–Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy (SHML) is a self-limiting, benign histiocytic disorder. We report a case of RDD mimicking lymphoma clinically and cytologically in a 3-year-old male child. The present case highlights the importance of cytology in the diagnosis of RDD along with cytological features of other differential diagnoses.

Rosai–Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy) of the Pancreas: Second Case Report

2008 ◽  
Vol 13 (4) ◽  
pp. 806-809 ◽  
Author(s):  
Sean P. Zivin ◽  
Mohammed Atieh ◽  
Michael Mosier ◽  
Gladell P. Paner ◽  
Gerard V. Aranha
Keyword(s):  
Case Report ◽  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

scholarly journals A case report of Rosai Dorfman disease

2018 ◽  
Vol 4 (3) ◽  
pp. 868
Author(s):  
Jyotika Waghray ◽  
Pradyut Waghray
Keyword(s):  
Lymph Node ◽  
Plasma Cells ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Lymph Node Involvement ◽  
Unknown Etiology ◽  
Low Grade ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Node Involvement

<p>Rosai-Dorfman’s disease also known as sinus histiocytosis with massive lymphadenopathy (SHML) is characterized by distorted lymph node architecture with marked dilation of lymphatic sinuses occupied by numerous lymphocytes, as well as histiocytes with vesicular nucleus and abundant clear cytoplasm with phagocytized lymphocytes or plasma cells, also known as ‘emperipolesis’. This disease of unknown etiology progresses with a benign prognosis strictly and only when an early diagnosis and treatment is made. A late diagnosis and a generalized lymph node involvement contribute to a poor prognosis. We reported a case of a 29-year-old Indian female with a 4-month history of painful unilateral cervical mass and low-grade fever with the final diagnosis of Rosai-Dorfman disease. The final diagnosis was made by fine needle aspiration (FNA) biopsy of the cervical lymph node. In conclusion, FNA biopsy can be enough to make the diagnosis in most cases due to the distinct cytological features of SHML, thereby avoiding more invasive approaches that potentially are unnecessary.</p>

A Solitary Rosai-Dorfman Disease of The Talus: The First Case Report of Bisphosphonate Therapy with Imaging Follow-up

2021 ◽  
Vol 104 (12) ◽  
pp. 1988-1991
Keyword(s):  
Case Report ◽  
Clinical Symptoms ◽  
Bisphosphonate Therapy ◽  
Histological Feature ◽  
Ankle Pain ◽  
First Report ◽  
Osseous Lesion ◽  
First Case ◽  
Rosai Dorfman Disease

Rosai-Dorfman disease (RDD) manifesting as a solitary osseous lesion especially of talus bone is rare. The authors reported a 31-year-old Thai man who had chronic left ankle pain and the biopsy of his talar lesion demonstrated emperipolesis, the typical histological feature of RDD. He was treated with curettage and adjuvant bisphosphonate and appeared to show improvement in clinical symptoms and radiological evidence. To the authors’ knowledge, this is the first report of an intraosseous RDD lesion treated with bisphosphonate with imaging follow-up. Keywords: Rosai-Dorfman disease; Talus; Solitary; Radiology; Bisphosphonate

scholarly journals Rosai-Dorfman Disease Complicated by Autoimmune Hemolytic Anemia in a Child: A Case Report and Review of the Literature

2018 ◽  
Vol 11 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Amer A. Lardhi ◽  
Abdullah K. Al-Mutairi ◽  
Mohammed H. Al-Qahtani ◽  
Atheer K. Al-Mutairi
Keyword(s):  
Case Report ◽  
Hemolytic Anemia ◽  
Autoimmune Hemolytic Anemia ◽  
Female Child ◽  
Infectious Agents ◽  
Review Of The Literature ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Generalized Lymphadenopathy

Rosai-Dorfman disease is a rare histiocytic proliferative disorder that commonly presents with a massive lymphadenopathy and a variety of constitutional symptoms. Severe hemolytic anemia is an infrequent complication of this disease. Although the etiology of the condition is unknown, infectious agents including viruses have been implicated. We describe a 2-year-old female child who presented with fever, pallor, and generalized lymphadenopathy complicated by the development of autoimmune hemolytic anemia. A review of the literature of this condition is also provided.

Concomitant Occurrence of Sinus Histiocytosis With Massive Lymphadenopathy and Nodal Marginal Zone Lymphoma

2011 ◽  
Vol 135 (3) ◽  
pp. 390-393
Author(s):  
Changlee S Pang ◽  
David D Grier ◽  
Michael W Beaty
Keyword(s):  
Lymph Node ◽  
Marginal Zone ◽  
Lymphoproliferative Disorders ◽  
Marginal Zone Lymphoma ◽  
Sinus Histiocytosis ◽  
Unknown Etiology ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Children And Young Adults ◽  
Nodal Marginal Zone Lymphoma

Abstract Sinus histiocytosis with massive lymphadenopathy (SHML), also known as Rosai-Dorfman disease, is a rare self-limiting disorder of histiocytes with unknown etiology. Sinus histiocytosis with massive lymphadenopathy is most common in children and young adults and is characterized by painless lymphadenopathy. Histologically there is a proliferation of sinus histiocytes with lymphophagocytosis or emperipolesis. On rare occasions, SHML has been associated with lymphoma, usually involving different anatomic sites and developing at different times. We report a case of concomitant SHML and nodal marginal zone lymphoma involving the same lymph node without involvement of other nodal or extranodal sites. The presence of concomitant SHML within the lymph node involved by nodal marginal zone lymphoma may represent the responsiveness of SHML histiocytes to B-cell–derived cytokines in lymphoproliferative disorders. To our knowledge, this is the first description of concomitant occurrence of SHML and nodal marginal zone lymphoma.

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