Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque–triggered thrombus formation in humans
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Key Points Btk inhibitors specifically block platelet thrombus formation on atherosclerotic plaque but spare physiologic hemostasis. Irreversible Btk inactivation in platelets incapable of enzyme resynthesis allows low intermittent drug dosing for antiatherothrombosis.
2019 ◽
Vol 3
(23)
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pp. 4021-4033
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2021 ◽
Vol 32
(12)
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pp. 1013-1031
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2018 ◽
Vol 11
(9)
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pp. 749-756
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2018 ◽
Vol 2
(14)
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pp. 1680-1684
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