Wang X, Haylock D, Hu CS, et al. A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells. Blood. 2016;127(26):3398-3409.

Key Points Treatment of MF CD34+ cells with a TPO receptor antagonist selectively depletes MF HSCs and HPCs. Agents that target the TPO receptor represent potentially new approaches for the treatment of MF patients.

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The Aryl Hydrocarbon Receptor Antagonist StemRegenin1 Improves In Vitro Generation of Highly Functional Natural Killer Cells from CD34+Hematopoietic Stem and Progenitor Cells

Stem Cells and Development ◽

10.1089/scd.2014.0597 ◽

2015 ◽

Vol 24 (24) ◽

pp. 2886-2898 ◽

Cited By ~ 17

Author(s):

Mieke W.H. Roeven ◽

Soley Thordardottir ◽

Arwa Kohela ◽

Frans Maas ◽

Frank Preijers ◽

...

Keyword(s):

Natural Killer Cells ◽

Receptor Antagonist ◽

Aryl Hydrocarbon Receptor ◽

Natural Killer ◽

Progenitor Cells ◽

Hematopoietic Stem ◽

Aryl Hydrocarbon ◽

Stem And Progenitor Cells ◽

Aryl Hydrocarbon Receptor Antagonist

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Engraftment and Lineage Potential of Adult Hematopoietic Stem and Progenitor Cells Is Compromised Following Short-Term Culture in the Presence of an Aryl Hydrocarbon Receptor Antagonist

Human Gene Therapy Methods ◽

10.1089/hgtb.2014.043 ◽

2014 ◽

Vol 25 (4) ◽

pp. 221-231 ◽

Cited By ~ 5

Author(s):

Angel Gu ◽

Monica Torres-Coronado ◽

Chy-Anh Tran ◽

Hieu Vu ◽

Elizabeth W. Epps ◽

...

Keyword(s):

Receptor Antagonist ◽

Aryl Hydrocarbon Receptor ◽

Progenitor Cells ◽

Short Term ◽

Hematopoietic Stem ◽

Aryl Hydrocarbon ◽

Stem And Progenitor Cells ◽

Short Term Culture ◽

Aryl Hydrocarbon Receptor Antagonist

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Flow cytometric enumeration and immunophenotyping of hematopoietic stem and progenitor cells

Seminars in Hematology ◽

10.1053/shem.2001.21925 ◽

2001 ◽

Vol 38 (2) ◽

pp. 139-147

Author(s):

Jan W. Gratama ◽

D. Robert Sutherland ◽

Michael Keeney

Keyword(s):

Progenitor Cells ◽

Hematopoietic Stem ◽

Flow Cytometric ◽

Stem And Progenitor Cells

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Detecting Human CD34 + and CD34 - Hematopoietic Stem and Progenitor Cells Using a Sysmex Automated Hematology Analyzer

Laboratory Hematology ◽

10.1532/lh96.04057 ◽

2004 ◽

Vol 10 (4) ◽

pp. 200-205 ◽

Cited By ~ 5

Author(s):

F. S. WANG ◽

R. M. ROWAN ◽

M. CREER ◽

A. HAY ◽

M. DORFNER ◽

...

Keyword(s):

Progenitor Cells ◽

Hematopoietic Stem ◽

Human Cd34 ◽

Hematology Analyzer ◽

Stem And Progenitor Cells ◽

Automated Hematology Analyzer

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Faculty Opinions recommendation of Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11493958.12528059 ◽

2011 ◽

Author(s):

Devendra Agrawal ◽

Vineet Agrawal

Keyword(s):

Bone Marrow ◽

Stem Cell ◽

Mesenchymal Stem Cell ◽

Progenitor Cells ◽

Stem Cell Niche ◽

Hematopoietic Stem ◽

Stem And Progenitor Cells ◽

Cell Niche

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Faculty Opinions recommendation of The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1158714.618930 ◽

2009 ◽

Author(s):

Michael Lassner ◽

Antoni Rafalski

Keyword(s):

Gene Expression ◽

Copy Number Variation ◽

Progenitor Cells ◽

Copy Number ◽

Hematopoietic Stem ◽

Stem And Progenitor Cells ◽

Number Variation ◽

The Impact

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Faculty Opinions recommendation of Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725415915.793507656 ◽

2015 ◽

Author(s):

Roger Patient ◽

Romualdo Ciau-Uitz

Keyword(s):

Progenitor Cells ◽

Hematopoietic Stem ◽

Stem And Progenitor Cells

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Enhanced thrombin/PAR1 activity promotes G-CSF- and AMD3100-induced mobilization of hematopoietic stem and progenitor cells via NO upregulation

Leukemia ◽

10.1038/s41375-021-01194-5 ◽

2021 ◽

Author(s):

Neta Nevo ◽

Lizeth-Alejandra Ordonez-Moreno ◽

Shiri Gur-Cohen ◽

Francesca Avemaria ◽

Suditi Bhattacharya ◽

...

Keyword(s):

Progenitor Cells ◽

Hematopoietic Stem ◽

Stem And Progenitor Cells

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3026 – METABOLIC ADAPTATION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS DURING EMERGENCY MYELOPOIESIS

Experimental Hematology ◽

10.1016/j.exphem.2020.09.046 ◽

2020 ◽

Vol 88 ◽

pp. S46

Author(s):

Oakley Olson ◽

Fernando Calero-Nieto ◽

Xiaonan Wang ◽

Bethold Göttgens ◽

Emmanuelle Passegué

Keyword(s):

Progenitor Cells ◽

Metabolic Adaptation ◽

Hematopoietic Stem ◽

Stem And Progenitor Cells ◽

Emergency Myelopoiesis

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