Differences in Psychological Factors Between Patients with Left Heart Failure and Right Heart Failure Associated with Chronic Obstructive Pulmonary Disease

Author(s):  
Karla Leticia Rosales Castillo ◽  
Viridiana Peláez Hernández ◽  
Laura Arely Martínez-Bautista ◽  
Arturo Orea-Tejeda ◽  
Karen Aide Santillán-Reyes ◽  
...  
Author(s):  
Alan Aldair Ibarra Fernández ◽  
Dulce González Islas ◽  
Arturo Orea Tejeda ◽  
Fernanda Salgado Fernández ◽  
Angelia Jiménez Valetín ◽  
...  

Global Heart ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e44 ◽  
Author(s):  
A. Orea-Tejeda ◽  
K.E. Katya E Bozada-Gutiérrez ◽  
D. González-Islas ◽  
B. Santellano-Suárez ◽  
C. Cintora-Martínez ◽  
...  

2020 ◽  
Author(s):  
Kang Li ◽  
Ningning Tao ◽  
Mingming Pan ◽  
Jingjing Liu ◽  
Ting Pan ◽  
...  

Abstract Background: Exacerbations are important events when managing chronic obstructive pulmonary disease (COPD) because they negatively impact disease progression. Inhaled corticosteroid (ICS) usage in patients with COPD is controversial. Therefore, we reviewed the benefits and risks of regular ICS treatment in patients with COPD regarding hospitalized acute exacerbation.Methods: This retrospective multicenter study—conducted in 18 medical centers across China—included 1,862 participants from 34 hospitals in northern China. Baseline characteristics, comorbidities, and administered medicines in the last year were matched using 1:1 propensity score-matching. We reviewed electronic patient medical records to ascertain symptoms, tests, in-hospital treatment, and prognosis. Subsequently, we reviewed computed tomography imaging results and pathogen identification tests.Results: Patients who used ICS in the past year presented more severe respiratory symptoms during acute exacerbations of COPD but less frequent right heart failure or consciousness disturbance. More antibiotics were used during hospitalization, resulting in higher costs; however, their prognosis was not different from patients who did not use ICS. Additionally, although ICS usage could increase gram-negative bacilli in sputum smears, it did not increase the probability of pulmonary infection.Conclusions: ICS use could protect patients from right heart failure, without detrimentally affecting prognosis during hospitalized exacerbations. Therefore, the risk of cardiovascular disease should be taken into consideration when making decisions regarding the potential administration of ICS in patients with COPD.


2017 ◽  
Vol 26 (12) ◽  
pp. 2988-2993 ◽  
Author(s):  
Arturo Orea-Tejeda ◽  
Katya Bozada-Gutiérrez ◽  
Juan Pineda-Juárez ◽  
Dulce González-Islas ◽  
Brenda Santellano-Juárez ◽  
...  

Angiology ◽  
2001 ◽  
Vol 52 (5) ◽  
pp. 317-322 ◽  
Author(s):  
Niyazi Güler ◽  
Mehmet Bilge ◽  
Beyhan Eryonucu ◽  
Kürcat Uzun ◽  
Mehmet Emin Avci ◽  
...  

Cardiac troponin levels are regarded as the most specific of currently available biochemical markers of myocardial damage. Elevated levels of troponin have been previously reported in patients with left heart failure, reflecting small areas of undetected myocardial cell death. The aim of this study was to compare the levels of the cardiac troponin I (cTnl) in patients with left- and right-sided heart failure. Cardiac troponin I levels were studied with immunochemical methods in patients with right heart failure (n = 17) resulting from chronic obstructive pulmonary disease, ischemic left heart failure (n = 23), and nonischemic left heart failure (n = 18) who were admitted to departments of cardiology and chest diseases. Also, cTnl levels were measured in 32 healthy subjects as control group. Protein markers of myocardial injury (cTnl and myoglobin) in patients with left and right heart failure were collected approximately 12 to 36 hours after onset of obvious symptoms. Serum creatine kinase MB band was determined on admission and thereafter twice a day during the first 3 days. Elevated levels of serum cTnl were found in patients with nonischemic (0.83 ±0.6 ng/mL, p<0.01) and ischemic left heart failure (0.9 ±0.5 ng/mL, p<0.01) when compared to healthy subjects, whereas serum cTnl levels in patients with right heart failure due to chronic obstruc tive pulmonary disease were not significantly different from those of control subjects (0.22 ±0.1 vs 0.16 ±0.1 ng/mL, p> 0.05). In addition, creatine kinase MB band and myoglobin levels were not significantly different between patient and healthy groups. The mean of cTnl levels in ischemic and even nonischemic left heart failure were increased compared to the mean of values in healthy individuals but without significant creatine kinase MB band and myoglobin elevations. But cTnl levels were not increased in patients with right heart failure due to chronic obstructive pulmonary disease. These data indicate that the cTnl levels are abnormal in left heart failure but not in cor pulmonale.


Kardiologiia ◽  
2019 ◽  
Vol 59 (10S) ◽  
pp. 4-12
Author(s):  
T. A. Dzyurich ◽  
A. I. Chesnikova ◽  
V. P. Terentyev ◽  
O. E. Kolomatskaya ◽  
V. A. Safronenko

Aim. Assess the diagnostic significance of markers of heart failure, to identify the features of clinical symptoms and structural and functional remodeling of the left and right heart in patients with chronic heart failure (CHF) in combination with atrial fibrillation (AF) and chronic obstructive pulmonary disease (COPD). Materials and methods. groups of patients were formed: group 1 – patients with COPD without cardiovascular diseases (n=28), group 2 – patients with CHF and COPD without AF (n=30), group 3 – patients with CHF and AF without COPD (n=33), group 4 (main) – patients with CHF, AF and COPD (n=29). Patients were evaluated for clinical symptoms, 6-minute walk test, echocardiographic study, determined the concentration of natriuretic peptides (NUP): N-terminal fragment of the precursor of cerebral NUP (NT-proBNP) and mid-regional pro-atrial NUP (MR-proANP). Results. In patients with CHF on the background of AF and COPD, a higher score of the severity of clinical symptoms was established in comparison with the 3rd group (p<0,001). The features of heart remodeling in patients of the main group were revealed in comparison with patients with CHF and AF without COPD: lower volume indices of the left (p=0,001) and right (p=0,004) atria and values of the indexed index of the end-diastolic area of the right ventricle (RV) (p=0,007), lower contractility of the RV, the presence of RV hypertrophy. The effect of AF on the structural and functional parameters of the heart in patients with CHF, COPD and AF can be judged by comparison with patients with CHF and COPD without AF: higher values of the size of the RV (p=0,012), indexed index of the end-systolic area of the RV (p<0,001), lower systolic function of the RV on the background of higher pressure in the RV cavity (p=0,001). Defined the highest level of NT-proBNP in patients with CHF, AF and COPD in comparison with its level in patients of the 2nd group (p<0,001) and in patients 3rd groups (p=0,010). Higher levels of MR-proANP were found in patients with CHF and AF without COPD (p<0,001). Conclusion. In patients with CHF, AF and COPD, more pronounced clinical symptoms are caused by chronic bronchial obstruction. Pathogenetic features of left and right heart remodeling in patients with CHF on the background of AF and COPD were revealed. For the early detection of HF in patients with AF the greatest diagnostic importance is the determination of the level of MR-proANP, however, in patients with combined AF and COPD the most informative is the determination of the concentration of NT-proBNP.


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