Work productivity loss in patients with dry eye disease: an online survey

ObjectivesTo compare sociodemographics and vision-related quality of life (QoL) of individuals with or without dry eye disease (DED); and to explore the impact of DED symptom severity on visual function, activity limitations and work productivity.DesignCross-sectional web-based survey.SettingGeneral UK population.ParticipantsAdults ≥18 years with (N=1002) or without (N=1003) self-reported DED recruited through email and screened.Main outcome measuresAll participants completed the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), with six additional questions (items A3–A8), and the EuroQol 5 dimensions 5 levels. DED participants also completed Impact of Dry Eye on Everyday Life questionnaire, 5-item Dry Eye Questionnaire and the Standardised Patient Evaluation of Eye Dryness questionnaire along with the Ocular Comfort Index, Work Productivity and Activity Impairment and the Eye Dryness Score (EDS), a Visual Analogue Scale.ResultsBaseline demographic and clinical characteristics were similar in participants with versus without DED (mean age, 55.2 vs 55.0 years; 61.8% vs 61.0% women, respectively) based on recruitment targets. Scores were derived from NEI VFQ-25 using the new 28-item revised VFQ (VFQ-28R) scoring. Mean (SD) VFQ-28R scores were lower in participants with versus without DED, indicating worse functioning (activity limitations, 73.3 (12.3) vs 84.4 (12.3); socioemotional functioning, 75.3 (21.5) vs 90.3 (16.2); total score, 71.6 (12.8) vs 83.6 (12.6)). Higher percentages of problems/inability to do activities were observed among those with versus without DED. The impact of DED on visual function was worse for participants with more severe DED symptoms, as assessed by EDS. In addition, a higher EDS was associated with worse symptoms on common DED scales and a worse impact on work productivity.ConclusionsDED symptoms were associated with negative effects on visual function, activities and work productivity, whereas worse DED symptoms had a greater impact on vision-related QoL and work productivity.

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Impact of Dry Eye Disease on Work Productivity, and Patients' Satisfaction With Over-the-Counter Dry Eye Treatments

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.16-19419 ◽

2016 ◽

Vol 57 (7) ◽

pp. 2975 ◽

Cited By ~ 18

Author(s):

Kelly K. Nichols ◽

Jason Bacharach ◽

Edward Holland ◽

Thomas Kislan ◽

Lee Shettle ◽

...

Keyword(s):

Dry Eye ◽

Work Productivity ◽

Dry Eye Disease ◽

Eye Disease ◽

Over The Counter ◽

Patients Satisfaction

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PP47 Defining The Needs And Preferences Of Patients With Dry Eye Disease

International Journal of Technology Assessment in Health Care ◽

10.1017/s026646231800209x ◽

2018 ◽

Vol 34 (S1) ◽

pp. 83-84 ◽

Cited By ~ 1

Author(s):

Nigel Cook ◽

Brigitte Sloesen ◽

Anna Panapurina ◽

Gary Johnson ◽

Clementine Prince ◽

...

Keyword(s):

Qualitative Research ◽

Dry Eye ◽

Convergent Validity ◽

Online Survey ◽

Dry Eye Disease ◽

Eye Disease ◽

Health States ◽

Total N ◽

Preference Structures ◽

The Impact

Introduction:Dry eye disease (DED) is a common condition that significantly impacts patients’ quality of life. Previous studies have explored the impact of DED on patients’ lives qualitatively; however, patients’ preference structures have not been thoroughly explored quantitatively.Methods:A targeted literature review and social media listening project guided design of a discussion guide for in-depth patient interviews (n=12). These, in turn, guided construction of a quantitative questionnaire administered to moderate to severe DED patients, 40 per country in Australia, Germany, United States and United Kingdom (total n=160). Patients’ preference structures were explored through an online survey using a self-explicated conjoint methodology, because of its high respondent-friendliness. Additionally, we administered the EQ5D-5L instrument to determine the health states/utilities of patients. Reaction to a hypothetical novel treatment was further obtained to check for convergent validity with the self-explicated conjoint. Finally, we asked respondents to rate the ease and relevance of the questionnaire to them.Results:Qualitative research uncovered important patient perspectives that were built into the quantitative survey. For example, patients seek medical advice when their symptoms are not improving. Patients’ lives are most affected by sensitivity to light, itchy and tired eyes and an inability to perform computer/screen work; however, of most concern/worrying to them is that their DED will get worse and they go blind. Results from the quantitative preference research will also be shared and its implications for future clinical trials in DED outlined. The results of the patient research and preference study are to be shared with health technology assessment (HTA) bodies and regulators through the early dialogue scientific advice process.Conclusions:A process of using qualitative research to determine what matters to patients and then quantification through respondent-friendly preference research can identify outcomes that are most patient-relevant, to inform future drug development strategies.

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Impact of Dry Eye Disease on Work Productivity Among Saudi Workers in Saudi Arabia

Clinical Ophthalmology ◽

10.2147/opth.s313158 ◽

2021 ◽

Vol Volume 15 ◽

pp. 2675-2681

Author(s):

Faris H Binyousef ◽

Shahad A Alruwaili ◽

Abdulaziz F Altammami ◽

Ahmed A Alharbi ◽

Feras A Alrakaf ◽

...

Keyword(s):

Saudi Arabia ◽

Dry Eye ◽

Work Productivity ◽

Dry Eye Disease ◽

Eye Disease

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The prevalence, severity, and risk factors for dry eye disease in Dubai – a cross sectional study

BMC Ophthalmology ◽

10.1186/s12886-021-01978-4 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Sarah Alkabbani ◽

Lakshmanan Jeyaseelan ◽

Anupama P. Rao ◽

Sandeep P. Thakur ◽

Pramod T. Warhekar

Keyword(s):

United Arab Emirates ◽

Dry Eye ◽

Online Survey ◽

Contact Lenses ◽

Cross Sectional Study ◽

Dry Eye Disease ◽

Eye Disease ◽

Sectional Study ◽

Cross Sectional ◽

Dry Eyes

Abstract Background The prevalence of dry eye disease is increasing globally and requires the attention of healthcare professionals as it worsens patients’ quality of life. No published studies on the epidemiology of dry eyes have been found in Dubai. Purpose To describe the epidemiology, prevalence, severity, and associated factors of dry eyes in Dubai, United Arab Emirates, in 2019. Methods This was an analytical, cross-sectional, survey-based study. An online survey was distributed by email to Mohammed Bin Rashid University students, staff, and faculty and to the staff at Mediclinic City and Parkview Hospitals in Dubai, United Arab Emirates, from April–June 2019. The survey included demographic questions and the Ocular Surface Disease Index (OSDI). Results The survey was completed by 452 participants; the majority were females (288/452; 63.7 %). The prevalence of dry eyes in Dubai was estimated to be 62.6 % (283/452), with severely dry eyes being the most prevalent (119/283; 42 %). Females, high daily screen time (> 6 h), and the use of contact lenses were found to be associated with dry eyes (P-value < 0.05, 95 % confidence interval). Age was found to be negatively correlated with prevalence of dry eyes. Exposure to smoking/shisha, history of eye injury/surgery, and nationality were not associated with dry eyes. Conclusions This is the first cross-sectional study to investigate the prevalence of dry eyes in Dubai (62.6 %). The majority of participants had severe dry eyes symptoms. Severely dry eyes were more common among females and users of contact lenses.

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