scholarly journals SNPs detection in DHPS-WDR83 overlapping genes mapping on porcine chromosome 2 in a QTL region for meat pH

BMC Genetics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 99 ◽  
Author(s):  
Paolo Zambonelli ◽  
Roberta Davoli ◽  
Mila Bigi ◽  
Silvia Braglia ◽  
Luigi Francesco De Paolis ◽  
...  
Keyword(s):  
Chromosome 2 ◽  
Overlapping Genes ◽  
Porcine Chromosome ◽  
Meat Ph

scholarly journals Characterization, Tissue Expression, and Imprinting Analysis of the Porcine CDKN1C and NAP1L4 Genes

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Shun Li ◽  
Juan Li ◽  
Jiawei Tian ◽  
Ranran Dong ◽  
Jin Wei ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Small Intestine ◽  
Candidate Genes ◽  
Tissue Specificity ◽  
Mammalian Species ◽  
Tissue Expression ◽  
Chromosome 2 ◽  
Porcine Chromosome ◽  
Rt Pcr ◽  
Lung And Kidney

CDKN1C and NAP1L4 in human CDKN1C/KCNQ1OT1 imprinted domain are two key candidate genes responsible for BWS (Beckwith-Wiedemann syndrome) and cancer. In order to increase understanding of these genes in pigs, their cDNAs are characterized in this paper. By the IMpRH panel, porcine CDKN1C and NAP1L4 genes were assigned to porcine chromosome 2, closely linked with IMpRH06175 and with LOD of 15.78 and 17.94, respectively. By real-time quantitative RT-PCR and polymorphism-based method, tissue and allelic expression of both genes were determined using F1 pigs of Rongchang and Landrace reciprocal crosses. The transcription levels of porcine CDKN1C and NAP1L4 were significantly higher in placenta than in other neonatal tissues (P<0.01) although both genes showed the highest expression levels in the lung and kidney of one-month pigs (P<0.01). Imprinting analysis demonstrated that in pigs, CDKN1C was maternally expressed in neonatal heart, tongue, bladder, ovary, spleen, liver, skeletal muscle, stomach, small intestine, and placenta and biallelically expressed in lung and kidney, while NAP1L4 was biallelically expressed in the 12 neonatal tissues examined. It is concluded that imprinting of CDKN1C is conservative in mammals but has tissue specificity in pigs, and imprinting of NAP1L4 is controversial in mammalian species.

Partial molecular characterization and mapping of the GDF9 gene to porcine chromosome 2

2004 ◽  
Vol 35 (3) ◽  
pp. 261-262 ◽  
Author(s):  
S. Cepica ◽  
R. Prochazka ◽  
K. Civanova ◽  
A. Knoll ◽  
L. Nemcova ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Chromosome 2 ◽  
Porcine Chromosome ◽  
Gdf9 Gene

scholarly journals Fine-mapping of a QTL influencing pork tenderness on porcine chromosome 2

BMC Genetics ◽  
2007 ◽  
Vol 8 (1) ◽  
pp. 69 ◽  
Author(s):  
Stacey N Meyers ◽  
Sandra L Rodriguez-Zas ◽  
Jonathan E Beever
Keyword(s):  
Fine Mapping ◽  
Chromosome 2 ◽  
Porcine Chromosome

Development of a single nucleotide polymorphism map of porcine chromosome 2

2003 ◽  
Vol 34 (6) ◽  
pp. 429-437 ◽  
Author(s):  
B. J. Jungerius ◽  
A. P. Rattink ◽  
R. P. M. A. Crooijmans ◽  
J. J. van der Poel ◽  
B. A. van Oost ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Chromosome 2 ◽  
Nucleotide Polymorphism ◽  
Porcine Chromosome ◽  
Single Nucleotide

Mapping of the prolactin gene to chicken chromosome 2

1999 ◽  
Vol 30 (6) ◽  
pp. 462-478 ◽  
Author(s):  
Y-W Miao ◽  
D W Burt ◽  
I R Paton ◽  
P J Sharp ◽  
I C Dunn
Keyword(s):  
Chromosome 2 ◽  
Chicken Chromosome ◽  
Prolactin Gene

scholarly journals Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.

Genetics ◽  
1989 ◽  
Vol 122 (3) ◽  
pp. 669-679
Author(s):  
L D Siracusa ◽  
A M Buchberg ◽  
N G Copeland ◽  
N A Jenkins
Keyword(s):  
Molecular Markers ◽  
Inbred Strain ◽  
Mouse Chromosome ◽  
Recombinant Inbred ◽  
Recombinant Inbred Strain ◽  
Interspecific Backcross ◽  
Chromosome 2 ◽  
Chromosome 4 ◽  
Agouti Locus ◽  
Mouse Chromosome 2

Abstract Recombinant inbred strain and interspecific backcross mice were used to create a molecular genetic linkage map of the distal portion of mouse chromosome 2. The orientation and distance of the Ada, Emv-13, Emv-15, Hck-1, Il-1a, Pck-1, Psp, Src-1 and Svp-1 loci from the beta 2-microglobulin locus and the agouti locus were established. Our mapping results have provided the identification of molecular markers both proximal and distal to the agouti locus. The recombinants obtained provide valuable resources for determining the direction of chromosome walking experiments designed to clone sequences at the agouti locus. Comparisons between the mouse and human genome maps suggest that the human homolog of the agouti locus resides on human chromosome 20q. Three loci not present on mouse chromosome 2 were also identified and were provisionally named Psp-2, Hck-2 and Hck-3. The Psp-2 locus maps to mouse chromosome 14. The Hck-2 locus maps near the centromere of mouse chromosome 4 and may identify the Lyn locus. The Hck-3 locus maps near the distal end of mouse chromosome 4 and may identify the Lck locus.

scholarly journals cot1: A Regulator of Arabidopsis Trichome Initiation

Genetics ◽  
1998 ◽  
Vol 149 (2) ◽  
pp. 565-577
Author(s):  
Daniel B Szymanski ◽  
Daniel A Klis ◽  
John C Larkin ◽  
M David Marks
Keyword(s):  
Cell Fate ◽  
Gene Dosage ◽  
Signal Transduction Pathway ◽  
Spatial Arrangement ◽  
Complex Signal ◽  
Chromosome 2 ◽  
Wild Type ◽  
Trichome Formation ◽  
In The Wild ◽  
Leaf Trichome

Abstract In Arabidopsis, the timing and spatial arrangement of trichome initiation is tightly regulated and requires the activity of the GLABROUS1 (GL1) gene. The COTYLEDON TRICHOME 1 (COT1) gene affects trichome initiation during late stages of leaf development and is described in this article. In the wild-type background, cot1 has no observable effect on trichome initiation. GL1 overexpression in wild-type plants leads to a modest number of ectopic trichomes and to a decrease in trichome number on the adaxial leaf surface. The cot1 mutation enhances GL1-overexpression-dependent ectopic trichome formation and also induces increased leaf trichome initiation. The expressivity of the cot1 phenotype is sensitive to cot1 and 35S::GL1 gene dosage, and the most severe phenotypes are observed when cot1 and 35S::GL1 are homozygous. The COT1 locus is located on chromosome 2 15.3 cM north of er. Analysis of the interaction between cot1, try, and 35S::GL1 suggests that COT1 is part of a complex signal transduction pathway that regulates GL1-dependent adoption of the trichome cell fate.

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